Common Stock Equity Components [Axis] Preferred Stock Additional Paid-In Capital Accumulated Deficit During Development Stage Convertible notes Antidilutive Securities [Axis] Series B non-voting preferred stock Shares underlying outstanding warrants Shares underlying outstanding stock options Issued to co-placement agents in connection with previous convertible note financings Class of Warrant or Right [Axis] Issued in connection with 2009 private placement Issued in connection with IPO Issued to IPO underwriters that, if exercised, would result in the issuance of an additional 4,812 shares of common stock and warrants to purchase an additional 2,406 shares of common stock Issued in connection with September 20, 2012 private placement of convertible notes Issued to placement agent in connection with September 20, 2012 private placement of convertible notes Issued in connection with November 13, 2012 private placement of convertible notes Issued to placement agent in connection with November 13, 2012 private placement of convertible notes Issued in connection with February 2013 private placement Deferred Stock Issuances Issued in connection with license agreement amendment Issued in connection with July private placement Issued in connection with May 2013 Private Placement Document And Entity Information Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Is Entity a Well-known Seasoned Issuer? Is Entity a Voluntary Filer? Is Entity's Reporting Status Current? Entity Filer Category Entity Public Float Entity Common Stock, Shares Outstanding Document Fiscal Period Focus Document Fiscal Year Focus Statement of Financial Position [Abstract] ASSETS Current assets Cash Restricted cash Prepaid research and development expenses Inventories Deferred financing costs Other prepaid expenses and current assets Total current assets Property and equipment, net Security deposit TOTAL ASSETS LIABILITIES AND STOCKHOLDERS EQUITY Current liabilities Accounts payable Accrued expenses Accrued interest, related parties Senior convertible notes, net of debt discount of $647,939 at December 31, 2012 Senior convertible notes - related parties, net of debt discount of $4,015 at September 30, 2013 and $406,316 at December 31, 2012 8% senior convertible notes, net of original issue discount of $10,124 at September 30, 2013 and $0 at December 31, 2012 8% senior convertible notes, related party, net of original issue discount of $25,416 at September 30, 2013 and $0 at December 31, 2012 Warrant Liability Total current liabilities Deferred rent TOTAL LIABILITIES COMMITMENTS AND CONTINGENCIES STOCKHOLDERS' DEFICIT Preferred stock - $0.001 par value: 2,000,000 shares authorized, 454,546 and 0 shares issued and outstanding at September 30, 2013 and December 31, 2012, respectively Common stock - $0.001 par value: 80,000,000 shares authorized, 15,959,088 and 11,408,274 shares issued and outstanding at September 30, 2013 and December 31, 2012, respectively Deferred stock issuances Additional paid-in capital Deficit accumulated during the development stage TOTAL STOCKHOLDERS' DEFICIT TOTAL LIABILITIES AND STOCKHOLDERS' DEFICIT Convertible debt discount Convertible debt discount, related parties 8% senior convertible notes, net of original issue discount 8% senior convertible notes, related party original issue discount Preferred stock, par value Preferred stock, shares authorized Preferred stock, shares issued Preferred stock, shares outstanding Common stock, par value Common stock, shares authorized Common stock, shares issued Common stock, shares outstanding Income Statement [Abstract] OPERATING EXPENSES Research and development General and administrative Total Operating Expenses LOSS FROM OPERATIONS OTHER INCOME (EXPENSE) Other income, net Interest income Foreign currency gain (loss) Loss on issuance of convertible notes and warrants Change in fair value of convertible notes and warrants Loss on extinguishment of convertible notes Interest expense, including amortization and write-off of deferred financing costs and debt discounts LOSS BEFORE INCOME TAXES State income tax benefit NET LOSS Deemed dividend - beneficial conversion feature NET LOSS ATTRIBUTABLE TO COMMON SHAREHOLDERS NET LOSS PER SHARE - BASIC AND DILUTED WEIGHTED AVERAGE SHARES OUTSTANDING - BASIC AND DILUTED Statement [Table] Statement [Line Items] Beginning balance Beginning balance (in shares) Non-voting preferred stock issued in February 2013 private placement at $0.70 per share, net (in shares) Non-voting preferred stock issued in February 2013 private placement at $0.70 per share, net Conversion of Series A non-voting preferred stock to common stock (in shares) Conversion of Series A non-voting preferred stock to common stock Deemed dividend related to beneficial conversion feature of Series A non-voting preferred stock Non-voting preferred stock issued in July 2013 private placement at $1.10 per share, net Non-voting preferred stock issued in July 2013 private placement at $1.10 per share, net (in shares) Deemed dividend related to July 2013 private placement at $1.10 per share, net Repurchase of outstanding warrants Stock-based compensation Warrants issued in connection with license agreement Warrants issued in connection with license agreement (in shares) Stock issued in connection with 8% senior convertible note and interest conversion Stock issued in connection with 8% senior convertible note and interest conversion (in shares) Stock issued in connection with warrants exercised Stock issued in connection with warrants exercised (in shares) Net loss Ending balance (in shares) Ending balance Statement of Cash Flows [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: Adjustments to reconcile net loss to net cash used in operating activities: Stock-based compensation Stock issued in connection with license agreements Stock issued in connection with consulting agreement Amortization of deferred financing costs Amortization of debt discount Warrants issued in connection with license agreement Loss on issuance of convertible notes and warrants Non-cash loss on extinguishment of convertible notes Change in fair value of convertible notes and warrants Non-cash charge for beneficial conversion feature Non-cash interest expense Expenses paid on behalf of the Company satisfied through the issuance of notes Depreciation Changes in operating assets and liabilities: Restricted cash Prepaid expenses and other current assets Inventories Security deposits Accounts payable Accrued expenses and accrued interest Accrued interest, related parties Deferred rent Net cash used in operating activities CASH FLOWS FROM INVESTING ACTIVITIES: Purchase of equipment Net cash used in investing activities CASH FLOWS FROM FINANCING ACTIVITIES: Proceeds from notes payable to related parties Proceeds from senior convertible notes, net Proceeds from senior convertible notes, related party, net Proceeds from Galenica, Ltd. promissory note Proceeds from exercise of warrants Payments for deferred financing costs and private placement expenses Repayment of amounts loaned under related party notes Proceeds from sale of equity securities Proceeds from receipt of stock subscriptions and issuances of common stock Net cash provided by financing activities NET INCREASE (DECREASE) IN CASH CASH - BEGINNING OF PERIOD CASH - END OF PERIOD Cash paid for interest Supplemental Disclosure of Non-Cash Financing Activities: Conversion of notes payable and accrued interest to common stock Conversion of preferred stock to common stock Reclassification of deferred financing fees to additional paid-in capital Stock issued to technology finders and licensors Warrants issued to placement agent Debt discount on senior convertible notes Deemed dividend - beneficial conversion feature Accrued and unpaid deferred financing cost Accrued and unpaid private placement expenses Organization Business And Basis Of Presentation Organization, Business and Basis of Presentation Accounting Policies [Abstract] Summary of Significant Accounting Policies Debt Disclosure [Abstract] Convertible Notes Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Fair Value Measurements Fair Value Measurements Subsequent Events [Abstract] Subsequent Events Use of Estimates Basis of Consolidation Foreign Currency Restricted Cash Loss per common share Inventories Accrued Expenses Stock-Based Compensation Fair Value Option Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Inventories Accrued Expenses Convertible Notes Payable [Abstract] Fair Value Assumption of Warrant Issued Senior Convertible Notes and Warrants Additional Information Assumptions Used in Black-Scholes Option-Pricing Model Summary of Option Activity under Plan and Related Information Summary of warrants outstanding Organization Business And Basis Of Presentation Details Narrative Antidilutive Shares Raw materials Work-in-process Total Licensing fee Royalty fee Accrued payroll and payroll taxes Professional fees Accrued interest Other Total Convertible Notes Details Contractual Term Volatility Dividend yield Risk-free interest rate Convertible Notes Details 1 9% Senior convertible notes Debt discount/beneficial conversion feature Balance Accrued interest 9% Senior convertible notes, related parties Debt discount/beneficial conversion feature Balance Accrued interest, related parties 8% senior convertible notes at fair value 8% senior convertible notes at fair value, related party Accrued interest - 8% Senior convertible notes, related party Stockholders Equity Details Expected Term Expected Term Volatility, minimum Volatility, maximum Dividend yield Risk-free interest rate, minimum Risk-free interest rate, maximum Stockholders Equity Details 1 Number of Options Number of Options Outstanding Number of Options Forfeited Expired/Canceled Number of Options Granted Number of Options Exercised Number of Options Outstanding Vested and expected to vest Exercisable Weighted Average Exercise Price Weighted Average Exercise Price Outstanding, Beginning Weighted Average Exercise Price Forfeited Weighted Average Exercise Price Expired/Canceled Weighted Average Exercise Price Granted Weighted Average Exercise Price Exercised Weighted Average Exercise Price Outstanding, Ending Weighted Average Exercise Price vest Weighted Average Exercise Price Exercisable Weighted Average Remaining Contractual Life (in years) Weighted Average Remaining Contractual Life (in years) Outstanding, Beginning Weighted Average Remaining Contractual Life (in years) Outstanding, Ending Weighted Average Remaining Contractual Life (in years) Vested and expected to vest Weighted Average Remaining Contractual Life (in years) Exercisable Aggregate Intrinsic Value Weighted-average fair value of options granted during the period Aggregate Intrinsic Value vested and expected to vest Aggregate Intrinsic Value Exercisable Class of warrant or right, outstanding Class of warrant or right, exercise price of warrants or rights Class of warrant or right, Expiration date Accrued Deferred Financing Cost Accrued Private Placement Expenses Aggregate intrinsic value abstract Convertible Debt Accrued Interest Convertible Debt Discount Convertible Debt Gross Deemed Dividend Convertible Beneficial Conversion Feature Fair Value Measurements [Abstract] Issuance Of Common Stock Value For Service Noncash Charges and Other Number of options abstract Organization Business and Basis Of Presentation [Abstract] Related Party Convertible Debt Related Party Convertible Debt Discount Related Party Convertible Debt Gross Sharebased Compensation Shares Authorized Under Stock Option Plans Exercise Price Range Outstanding Options Weighted Average Remaining Contractual Term Stock and Warrants Issued During Period Shares Preferred Stock and Warrants Supplemental Conversion Of Convertible Notes To Stock Supplemental Discount On Note Payable Supplemental Noncash Transactions Supplemental Warrant Issued To Placement Agent and Investors In Private Placement Weighted average remaining contractual life in years abstract Assets, Current Assets Liabilities, Current Liabilities Deferred Compensation Equity Development Stage Enterprise, Deficit Accumulated During Development Stage Stockholders' Equity Attributable to Parent Liabilities and Equity Operating Expenses Interest Expense Income Tax Expense (Benefit) Shares, Outstanding Payments for Repurchase of Warrants Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Other Noncash Income (Expense) ExpenseWarrantsIssuedInConnectionWithLicenseAgreement Increase (Decrease) in Restricted Cash Increase (Decrease) in Prepaid Expense and Other Assets Increase (Decrease) in Inventories Increase (Decrease) in Deposits Outstanding Increase (Decrease) in Accounts Payable IncreaseDecreaseAccruedInterestRelatedParties Increase (Decrease) in Deferred Liabilities Net Cash Provided by (Used in) Operating Activities Payments to Acquire Property, Plant, and Equipment Net Cash Provided by (Used in) Investing Activities Payments of Financing Costs Repayments of Related Party Debt Net Cash Provided by (Used in) Financing Activities Cash and Cash Equivalents, Period Increase (Decrease) Fair Value Disclosures [Text Block] Inventory, Cash Flow Policy [Policy Text Block] Schedule of Inventory, Current [Table Text Block] Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] ConvertibleDebtAccruedInterest AccruedInterestRelatedParties ExpectedTerm Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price