101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - Condensed Consolidated Balance Sheets link:calculationLink link:presentationLink link:definitionLink 104 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss link:calculationLink link:presentationLink link:definitionLink 106 - Statement - Condensed Consolidated Statements of Cash Flows link:calculationLink link:presentationLink link:definitionLink 107 - Disclosure - BUSINESS OVERVIEW link:calculationLink link:presentationLink link:definitionLink 108 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - NET LOSS PER COMMON SHARE link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - ACCRUED EXPENSES link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - SHARE-BASED COMPENSATION link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - COLLABORATION link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - COMMITMENTS AND CONTINGENCIES link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies) link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - NET LOSS PER COMMON SHARE (Tables) link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - ACCRUED EXPENSES (Tables) link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - SHARE-BASED COMPENSATION (Tables) link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Business Overview - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - Basic and Diluted Net Loss Per Common Share (Detail) link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - Common Shares Excluded from Calculation of Basic and Diluted Net Loss Per Common Share (Detail) link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Component of Accrued Expenses (Detail) link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Other Long-Term Liabilities (Detail) link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Share-Based Compensation Expense (Detail) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Fair Value Per Share and Black-Scholes Option Pricing Model with Assumptions Used for Grants Issued (Detail) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Share-Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Summary of Option Activity under Equity Incentive Plans (Detail) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Collaboration - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Commitments and Contingencies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink