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  <xsd:element name="TypeOfContractAxis" id="twou_TypeOfContractAxis" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TypeOfContractDomain" id="twou_TypeOfContractDomain" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TwoContractsWithSameUniversityMember" id="twou_TwoContractsWithSameUniversityMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="OneContractWithUniversityMember" id="twou_OneContractWithUniversityMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CapitalizedContentDevelopmentCostsUsefulLife" id="twou_CapitalizedContentDevelopmentCostsUsefulLife" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RebateReserveAbstract" id="twou_RebateReserveAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="PeriodOfTeachingInDesignatedLowIncomeSchoolToGetRebate" id="twou_PeriodOfTeachingInDesignatedLowIncomeSchoolToGetRebate" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CapitalizedContentDevelopmentCostsAbstract" id="twou_CapitalizedContentDevelopmentCostsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ScheduleOfCapitalizedContentDevelopmentCostsTableTextBlock" id="twou_ScheduleOfCapitalizedContentDevelopmentCostsTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="PaymentsForCapitalizedContentCost" id="twou_PaymentsForCapitalizedContentCost" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="RefundsPayableCurrent" id="twou_RefundsPayableCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element name="RebateReserveNoncurrent" id="twou_RebateReserveNoncurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element name="InitialPublicOfferingAndProFormaPresentationPolicyTextBlock" id="twou_InitialPublicOfferingAndProFormaPresentationPolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AccountingPoliciesTable" id="twou_AccountingPoliciesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AccountingPoliciesLineItems" id="twou_AccountingPoliciesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="UnderwritingDiscountsAndCommissionsExpense" id="twou_UnderwritingDiscountsAndCommissionsExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="OfferingCosts" id="twou_OfferingCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="PreferredStockWarrantLiability" id="twou_PreferredStockWarrantLiability" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element name="EquityIncentivePlan2014Member" id="twou_EquityIncentivePlan2014Member" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RedeemableConvertibleSeriesAPreferredStockMember" id="twou_RedeemableConvertibleSeriesAPreferredStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RedeemableConvertibleSeriesBPreferredStockMember" id="twou_RedeemableConvertibleSeriesBPreferredStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RedeemableConvertibleSeriesCPreferredStockMember" id="twou_RedeemableConvertibleSeriesCPreferredStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RedeemableConvertibleSeriesDPreferredStockMember" id="twou_RedeemableConvertibleSeriesDPreferredStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="WarrantsToPurchaseSeriesCRedeemableConvertiblePreferredStockMember" id="twou_WarrantsToPurchaseSeriesCRedeemableConvertiblePreferredStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="WarrantsToPurchaseSeriesDRedeemableConvertiblePreferredStockMember" id="twou_WarrantsToPurchaseSeriesDRedeemableConvertiblePreferredStockMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="WeightedAverageNumberOfShareOutstandingBasicAndDilutedAbstract" id="twou_WeightedAverageNumberOfShareOutstandingBasicAndDilutedAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="OtherPreferredStockDividendsAndAdjustment" id="twou_OtherPreferredStockDividendsAndAdjustment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="WeightedAverageBasicAndDilutedSharesOutstandingProForma" id="twou_WeightedAverageBasicAndDilutedSharesOutstandingProForma" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CommonStockSoldBySellingStockholders" id="twou_CommonStockSoldBySellingStockholders" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="GrossProceedsFromIssuanceInitialPublicOffering" id="twou_GrossProceedsFromIssuanceInitialPublicOffering" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="WarrantToPurchaseSeriesDRedeemableConvertiblePreferredStockExpiringIn2022Member" id="twou_WarrantToPurchaseSeriesDRedeemableConvertiblePreferredStockExpiringIn2022Member" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="WarrantToPurchaseSeriesDRedeemableConvertiblePreferredStockExpiringIn2023Member" id="twou_WarrantToPurchaseSeriesDRedeemableConvertiblePreferredStockExpiringIn2023Member" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="WarrantsDisclosureTextBlock" id="twou_WarrantsDisclosureTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ClassOfWarrantOrRightAmountReclassifiedToAdditionalPaidInCapitalOnConversionOfWarrants" id="twou_ClassOfWarrantOrRightAmountReclassifiedToAdditionalPaidInCapitalOnConversionOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="ShareBasedCompensationArrangementsByShareBasedPaymentAwardNumberOfEmployeeCompensationPlans" id="twou_ShareBasedCompensationArrangementsByShareBasedPaymentAwardNumberOfEmployeeCompensationPlans" type="xbrli:integerItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardPeriodOfAnnualAutomaticIncreaseInSharesAuthorized" id="twou_ShareBasedCompensationArrangementByShareBasedPaymentAwardPeriodOfAnnualAutomaticIncreaseInSharesAuthorized" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageAppliedOnOutstandingSharesOfCommonStockForAutomaticInclusionInPlan" id="twou_ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageAppliedOnOutstandingSharesOfCommonStockForAutomaticInclusionInPlan" type="num:percentItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsWeightedAverageRemainingContractualTermAbstract" id="twou_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsWeightedAverageRemainingContractualTermAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodWeightedAverageRemainingContractualTerm" id="twou_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsGrantsInPeriodWeightedAverageRemainingContractualTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisesInPeriodWeightedAverageRemainingContractualTerm" id="twou_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisesInPeriodWeightedAverageRemainingContractualTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIntrinsicValueAbstract" id="twou_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsIntrinsicValueAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AdvanceToClientsCurrent" id="twou_AdvanceToClientsCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="AdvanceToClientsNoncurrent" id="twou_AdvanceToClientsNoncurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="TemporaryEquityTextBlock" id="twou_TemporaryEquityTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ScheduleOfIncreaseDecreaseInTemporaryEquityTableTextBlock" id="twou_ScheduleOfIncreaseDecreaseInTemporaryEquityTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TemporaryEquityConversionPricePerShare" id="twou_TemporaryEquityConversionPricePerShare" type="num:perShareItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CommonStockReservedForFutureIssuanceDisclosureAbstract" id="twou_CommonStockReservedForFutureIssuanceDisclosureAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CommonStockReservedForFutureIssuanceTextBlock" id="twou_CommonStockReservedForFutureIssuanceTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ScheduleOfSharesOfCommonStockReservedForFutureIssuanceTableTextBlock" id="twou_ScheduleOfSharesOfCommonStockReservedForFutureIssuanceTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceAbstract" id="twou_CommonStockCapitalSharesReservedForFutureIssuanceAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceConversionOfRedeemableConvertiblePreferredStock" id="twou_CommonStockCapitalSharesReservedForFutureIssuanceConversionOfRedeemableConvertiblePreferredStock" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceOutstandingStockOptions" id="twou_CommonStockCapitalSharesReservedForFutureIssuanceOutstandingStockOptions" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceOutstandingStockWarrants" id="twou_CommonStockCapitalSharesReservedForFutureIssuanceOutstandingStockWarrants" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuancePossibleFutureIssuanceUnderStockOptionPlans" id="twou_CommonStockCapitalSharesReservedForFutureIssuancePossibleFutureIssuanceUnderStockOptionPlans" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="CapitalStockSharesAuthorized" id="twou_CapitalStockSharesAuthorized" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="instant" />
  <xsd:element name="ServicingAndSupportCosts" id="twou_ServicingAndSupportCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="ServicingAndSupportMember" id="twou_ServicingAndSupportMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="TechnologyAndContentDevelopmentMember" id="twou_TechnologyAndContentDevelopmentMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="IncreaseDecreaseInAdvancesToClients" id="twou_IncreaseDecreaseInAdvancesToClients" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="IncreaseDecreaseInRefundsPayable" id="twou_IncreaseDecreaseInRefundsPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="IncreaseDecreaseInRebateReserve" id="twou_IncreaseDecreaseInRebateReserve" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="DocumentAndEntityInformationAbstract" id="twou_DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CapitalizedContentDevelopmentCostsNet" id="twou_CapitalizedContentDevelopmentCostsNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="CapitalizedContentDevelopmentCosts" id="twou_CapitalizedContentDevelopmentCosts" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CapitalizedContentDevelopmentCostsTextBlock" id="twou_CapitalizedContentDevelopmentCostsTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="ScheduleOfCapitalizedContentDevelopmentCostsFutureAmortizationExpenseTableTextBlock" id="twou_ScheduleOfCapitalizedContentDevelopmentCostsFutureAmortizationExpenseTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CapitalizedContentDevelopmentCostsFutureAmortizationExpenseCurrentAndFiveSucceedingFiscalYearsAbstract" id="twou_CapitalizedContentDevelopmentCostsFutureAmortizationExpenseCurrentAndFiveSucceedingFiscalYearsAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="FutureAmortizationExpensesRemainderOfFiscalYear" id="twou_FutureAmortizationExpensesRemainderOfFiscalYear" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="FutureAmortizationExpensesAfterYearFive" id="twou_FutureAmortizationExpensesAfterYearFive" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="OfferingCostsOfInitialPublicOffering" id="twou_OfferingCostsOfInitialPublicOffering" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="CommonStockGranted" id="twou_CommonStockGranted" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="OtherNoncurrentAssetsPolicyTextBlock" id="twou_OtherNoncurrentAssetsPolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RefundsPayablePolicyTextBlock" id="twou_RefundsPayablePolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="RebateReservePolicyTextBlock" id="twou_RebateReservePolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AdvancesToClientsPolicyTextBlock" id="twou_AdvancesToClientsPolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="CapitalizedContentDevelopmentCostsExcludingInProcessCostsGross" id="twou_CapitalizedContentDevelopmentCostsExcludingInProcessCostsGross" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="CapitalizedContentDevelopmentCostsInProcessGross" id="twou_CapitalizedContentDevelopmentCostsInProcessGross" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="AccumulatedAmortization" id="twou_AccumulatedAmortization" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element name="AmortizationExpenseOfCapitalizedContentDevelopmentCosts" id="twou_AmortizationExpenseOfCapitalizedContentDevelopmentCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="FutureAmortizationExpenseYearTwo1" id="twou_FutureAmortizationExpenseYearTwo1" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="FutureAmortizationExpenseYearThree1" id="twou_FutureAmortizationExpenseYearThree1" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="FutureAmortizationExpensesYearFour1" id="twou_FutureAmortizationExpensesYearFour1" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="FutureAmortizationExpenseYearFive1" id="twou_FutureAmortizationExpenseYearFive1" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="CapitalizedContentDevelopmentCostsExcludingInProcessCostsNet" id="twou_CapitalizedContentDevelopmentCostsExcludingInProcessCostsNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element name="PeriodBeginningWithinOfTeachingInDesignatedLowIncomeSchoolToGetRebate" id="twou_PeriodBeginningWithinOfTeachingInDesignatedLowIncomeSchoolToGetRebate" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="PaymentsForDeferredOfferingCosts" id="twou_PaymentsForDeferredOfferingCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="StockIssuedDuringPeriodSharesExerciseOfWarrantsToPurchaseCommonStock" id="twou_StockIssuedDuringPeriodSharesExerciseOfWarrantsToPurchaseCommonStock" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalConversionOfWarrants" id="twou_AdjustmentsToAdditionalPaidInCapitalConversionOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element name="TemporaryEquityConversionOfConvertibleSecurities" id="twou_TemporaryEquityConversionOfConvertibleSecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="InitialPublicOfferingPolicyTextBlock" id="twou_InitialPublicOfferingPolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="InitialPublicOfferingAbstract" id="twou_InitialPublicOfferingAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" nillable="true" xbrli:periodType="duration" />
  <xsd:element name="InterestExpenseOnFairValueAdjustmentOfWarrants" id="twou_InterestExpenseOnFairValueAdjustmentOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element name="NumberOfTradingDaysConsideredInVolumeWeightedAveragePriceOfCommonStock" id="twou_NumberOfTradingDaysConsideredInVolumeWeightedAveragePriceOfCommonStock" type="xbrli:durationItemType" substitutionGroup="xbrli:item" abstract="false" nillable="true" xbrli:periodType="duration" />
</xsd:schema>


