Proceeds from Sale of Convertible Preferred Stock Net of Issuance Costs
Proceeds from sale of convertible preferred stock, net of issuance costs
The cash inflow from sale of preferred stock identified as being convertible into another form of financial instrument, typically the entity's common stock, net of issuance costs.
Represents information pertaining to the type or class of series A-2 convertible preferred stock. Convertible redeemable preferred stock possess conversion and redemption features. The stock has redemption features which are outside the control of the issuer.
Series A2 Convertible Preferred Stock [Member]
Series A-2 Convertible Preferred Shares
Series A-2 preferred stock
Series A-3 Convertible Preferred Shares
Represents information pertaining to the type or class of series A-3 convertible preferred stock. Convertible redeemable preferred stock possess conversion and redemption features. The stock has redemption features which are outside the control of the issuer.
Series A-3 preferred stock
Series A3 Convertible Preferred Stock [Member]
Series A4 Convertible Preferred Stock [Member]
Series A-4 Convertible Preferred Shares
Represents information pertaining to the type or class of series A-4 convertible preferred stock. Convertible redeemable preferred stock possess conversion and redemption features. The stock has redemption features which are outside the control of the issuer.
Series A-4 preferred stock
Series A Convertible Preferred Shares
Series A preferred stock
Represents information pertaining to the type or class of series A convertible preferred stock. Convertible redeemable preferred stock possess conversion and redemption features. The stock has redemption features which are outside the control of the issuer.
Series A Convertible Preferred Stock [Member]
Represents information pertaining to the type or class of series B-1 convertible preferred stock. Convertible redeemable preferred stock possess conversion and redemption features. The stock has redemption features which are outside the control of the issuer.
Series B-1 Convertible Preferred Shares
Series B-1 Preferred Stock
Series B1 Convertible Preferred Stock [Member]
Represents information pertaining to the type or class of series B convertible preferred stock. Convertible redeemable preferred stock possess conversion and redemption features. The stock has redemption features which are outside the control of the issuer.
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Shares
Series B preferred stock
Share based Compensation Arrangement by Share based Payment Award Aggregate Intrinsic Value [Abstract]
Aggregate Intrinsic Value
Share-based Compensation Arrangement by Share-based Payment Award Number of Additional Shares Authorized Annual
Number of annual increase in additional shares authorized for issuance under an established share-based compensation plan.
Annual increase in number of additional shares authorized under the Plan through December 31, 2023
Number of additional shares authorized under the 2010 Plan
Represents the number of additional shares authorized for issuance under the 2010 Stock Incentive Plan.
Share Based Compensation Arrangement by Share Based Payment Award Number of Additional Shares Authorized from 2010 Stock Incentive Plan
Amendment Description
Share-based Compensation Arrangement by Share-based Payment Award Number of Additional Shares Authorized in Percentage Annual
Represents the annual increase in percentage of common stock, which is used to issue additional shares authorized for issuance under the established share-based compensation plan.
Percentage applied to the outstanding shares as annual increase in the number of shares authorized for issuance
Amendment Flag
Share Based Compensation Arrangement by Share Based Payment Award Restricted Stock Exercise of Options Nonvested Number
Shares of unvested restricted stock remaining from the early exercise of stock options
The number of non-vested restricted stock issued as a result of the option exercised, that validly exist and are outstanding as of the balance sheet date.
Share based Compensation Arrangement by Share based Payment Award Weighted Average Remaining Contractual Term [Abstract]
Weighted-Average Remaining Contractual Term
Represents the number of shares of special participation stock issued during the reporting period.
Special Participation Stock Issued During Period Shares
Issuance of special participation stock (in shares)
Special Participation Stock [Member]
Special Participation Preferred Shares
Special participation stock
Represents information pertaining to the temporary equity attributable to special participation stock, under which the entity have the right (but not an obligation) to repurchase, at the original purchase price.
Stock Incentive Plan 2010 [Member]
2010 Plan
Represents information pertaining to the 2010 Stock Incentive Plan.
2010 Plan
Stock Incentive Plan 2013 [Member]
2013 Plan
Represents information pertaining to the 2013 Stock Incentive Plan.
Represents the aggregate cost incurred directly with the issuance of an equity security.
Issuance of stock, issuance costs
Stock Issuance Costs
Issuance of convertible preferred stock, issuance costs
Stock Issued During Period Shares Conversion of Convertible Preferred Securities
Conversion of convertible preferred stock into common stock (in shares)
Represents the number of shares issued during the period upon the conversion of convertible preferred securities.
Stock Issued During Period Shares Conversion of Special Participation Stock
Settlement of Special Participation Preferred Shares (in shares)
Represents the number of shares issued during the period upon the conversion of special participation stock.
Number of shares of common stock issued in settlement of outstanding shares of Special Participation Stock
Settlement of special participation preferred shares (in shares)
Stock Issued During Period Shares New Issues to be Made Upon Underwriters Exercise of Option
Number of shares issued upon the exercise of option by underwriters
Represents the number of shares of common stock to be issued upon the exercise of option by underwriters.
Office and laboratory space leased (in square feet)
Area of Real Estate Property
Represents the number of shares issued related to the preferred stock subscription during the reporting period.
Stock Issued During Period Shares Preferred Stock Subscription
Issuance of shares related to preferred stock subscription (in shares)
Stock Issued During Period Value Conversion of Convertible Preferred Securities
Conversion of convertible preferred stock into common stock
Represents the value of stock issued during the period upon the conversion of convertible preferred securities.
Stock Issued During Period Value Preferred Stock Subscription
Issuance of shares related to preferred stock subscription
Represents the value of stock issued related to preferred stock subscription during the reporting period.
Preferred stock subscription
Temporary Equity Subscriptions
Represents the amount of securities classified as temporary equity that have been allocated to investors to buy. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable.
Vesting Period One [Member]
Percent vesting one calendar year from vesting start date
Represents the first vesting period of options.
Vesting Period Two [Member]
Percentage vesting on the first day of each month after one calendar year
Represents the second vesting period of options.
Current Fiscal Year End Date
Award Type [Axis]
Wholly Owned Subsidiary Parent Ownership Interest [Table]
Wholly Owned Subsidiary Parent Ownership Interest [Line Items]
Basis of Presentation
Principles of Consolidation
Concentrations of Credit Risk and Off Balance Sheet Risk [Policy Text Block]
Concentrations of Credit Risk and Off-Balance Sheet Risk
Disclosure of accounting policy for concentrations of credit risk and off-balance sheet risk.
Organizational Costs [Policy Text Block]
Organizational Costs
Disclosure of accounting policy for organizational costs.
NPM Pharma Inc [Member]
NPM
Represents information pertaining to NPM Pharma Inc. (NPM, a Canadian corporation).
Schedule of estimated useful lives of real estate assets
Schedule of Property Plant and Equipment Useful Life [Table Text Block]
Tabular disclosure of the useful life of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale.
Number of Wholly Owned Subsidiaries Requiring Consolidation
Number of wholly-owned subsidiaries requiring consolidation
Represents the number of wholly-owned subsidiaries requiring consolidation.
Research Agreement 2013 [Member]
Research agreement executed during 2013
Represents information pertaining to research agreement executed during 2013.
Research Agreement 2011 [Member]
Research agreement executed during 2011
Represents information pertaining to research agreement executed during 2011.
Revenue Recognition Milestone Method Number of Research Agreements
Number of research agreements
Represents the number of research agreements for which revenue is recognized as per milestone method of revenue recognition.
Upfront Payment Received
Upfront payment not representing substantive milestone
Represents the amount of upfront payment received under research agreements.
Document Period End Date
Revenue Recognition Milestone Method Number of Milestones Met
Number of milestones met
Represents the number of milestones met for recognition of revenue as per milestone method of revenue recognition.
Revenue Recognition Milestone Method Revenue Recognized Related to Upfront Payment
Amount recognized related to upfront payment
Represents the amount of consideration recognized during the period related to upfront payments under milestone method of revenue recognition.
Revenue Recognition Milestone Method Revenue Recognized Related to Other Milestones
Amount recognized related to other milestones
Represents the amount of consideration recognized during the period related to other milestones under milestone method of revenue recognition.
Amount of Federal Grant Awarded
Amount of federal grant awarded under QTDP
Represents the amount of federal grant awarded during the period.
Amount of Federal Grant Received and Recognized in Income
Amount of federal grant received and recognized in income
Represents the amount of federal grant received and recognized in income during the period.
Stock Issued During Period Value Preferred Stock Net of Issuance Costs
Issuance of convertible preferred stock, net of issuance costs
Represents the value of convertible preferred stock issued during the reporting period, net of issuance costs.
Represents the number of shares of convertible preferred stock issued during the reporting period, net of issuance costs.
Stock Issued During Period Shares Preferred Stock Net of Issuance Costs
Issuance of convertible preferred stock, net of issuance costs (in shares}
Deferred Tax Assets Operating Loss Carryforwards Domestic and State and Local
U.S. and state net operating loss carryforwards
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible domestic and state and local operating loss carryforwards.
Deferred Tax Assets Tax Deferred Expense Reserves and Accruals and Other Temporary Differences
Accruals and other temporary differences
Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from reserves and accruals and other temporary differences.
Entity [Domain]
Operating Loss and Tax Credit Carryforwards Limitations Period Over which Cumulative Changes in Ownership Interest of Significant Shareholders Considered
Period over which certain cumulative changes in the ownership interest of significant shareholders will be considered, subject to an annual limitation of net operating loss and tax credit carryforwards
Represents the period over which certain cumulative changes in the ownership interest of significant shareholders will be considered, subject to an annual limitation of net operating loss and tax credit carryforwards.
Operating Loss and Tax Credit Carryforwards Limitations Threshold Percentage of Cumulative Changes in Ownership Interest of Significant Shareholders Considered
Percentage of cumulative changes in the ownership interest of significant shareholders that will be considered, subject to an annual limitation of net operating loss and tax credit carryforwards
Represents the percentage of cumulative changes in the ownership interest of significant shareholders that will be considered, subject to an annual limitation of net operating loss and tax credit carryforwards.
Uncertain tax position
Amount recognized for uncertain tax positions, as of the balance sheet date.
Liability for Uncertain Tax Positions Current and Noncurrent
Arrangements and Non-arrangement Transactions [Domain]
Represents the value of Series A-2 preferred stock subscription not issued, net of issuance costs.
Series A2 Preferred Stock Subscription Issued Value Net of Issuance Costs
Proceeds from the sale of Series A-2 convertible preferred stock, net of issuance costs of $35
Proceeds from the sale of Series A-2 convertible preferred stock, net of issuance costs of $35 (in shares)
Represents the number of shares of Series A-2 preferred stock subscription issued, net of issuance costs.
Series A2 Preferred Stock Subscription Issued Shares Net of Issuance Costs
Represents the value of Series A-3 preferred stock subscription not issued.
Series A3 Preferred Stock Subscription Issued Value
Proceeds from the sale of Series A-3 convertible preferred stock
Series A3 Preferred Stock Subscription Issued Shares
Proceeds from the sale of Series A-3 convertible preferred stock (in shares)
Represents the number of shares of Series A-3 preferred stock subscription issued.
Series A4 Preferred Stock Subscription Issued Value
Proceeds from the sale of Series A-4 convertible preferred stock
Represents the value of Series A-4 preferred stock subscription not issued.
Series A4 Preferred Stock Subscription Issued Shares
Proceeds from the sale of Series A-4 convertible preferred stock (in shares)
Represents the number of shares of Series A-4 preferred stock subscription issued.
Series B Preferred Stock Subscription Issued Value
Proceeds from the sale of Series B convertible preferred stock
Represents the value of Series B preferred stock subscription not issued.
Series B Preferred Stock Subscription Issued Shares
Proceeds from the sale of Series B convertible preferred stock (in shares)
Represents the number of shares of Series B preferred stock subscription issued.
Stock Issued During Period Value Preferred Stock
Issuance of convertible preferred stock
Represents the value of convertible preferred stock issued during the reporting period.
Total cash consideration for preferred stock issued and sold
Stock Issued During Period Shares Preferred Stock
Issuance of convertible preferred stock (in shares)
Represents the number of shares of convertible preferred stock issued during the reporting period.
Number of preferred stock issued and sold
Stock Issued During Period Value Conversion of Special Participation Stock
Settlement of special participation preferred shares
Represents the value of shares issued during the period upon the settlement of special participation stock.
Number of Advisors
Number of advisors
Represents the number of advisors of the entity.
Number of Tranches
Number of tranches
Represents the number of tranches in which stocks are issued.
Stock Repurchase Program Number of Closings
Number of closings under stock purchase agreement
Represents the number of closings under the stock purchase agreement.
Stock Agreed to be Issued During Period Shares Preferred Stock
Number of shares agreed to sell under the agreement
Represents the number of shares agreed to be issued by the entity under the agreement.
Stock Agreed to be Issued During Period Value Preferred Stock
Value of shares agreed to sell under the agreement
Represents the value of shares agreed to be issued by the entity under the agreement.
Number of Additional Shares Obligated to Purchase by Existing Investors
Number of additional shares obligated to purchase by the existing investors
Represents the number of additional shares obligated to purchase by the existing investors of the entity.
Value of Additional Shares Obligated to Purchase by Existing Investors
Proceeds from additional shares issued, which was obligated to purchase by the existing investors
Represents the proceeds from additional shares issued, which was obligated to purchase by the existing investors of the entity.
Special Participation Stock Number of Shares Authorized for Issuance
Number of shares of Special Participation Stock authorized for issuance
Represents the number of shares of special participation stock authorized for issuance during the period.
Special Participation Stock Number of Shares Outstanding
Outstanding shares of Special Participation Stock
Represents the number of shares of special participation stock outstanding as of the balance sheet date.
Series A preferred stock tranche one
Represents information pertaining to the tranche one of Series A convertible preferred stock.
Series A Convertible Preferred Stock Tranche One [Member]
Series A Convertible Preferred Stock Tranche Two [Member]
Series A preferred stock tranche two
Represents information pertaining to the tranche two of Series A convertible preferred stock.
Founders [Member]
Founders
Represents information pertaining to founders of the entity.
Advisors [Member]
Advisors
Represents information pertaining to advisors of the entity.
Research and development costs
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development costs. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Accrued Research and Development Costs, Current
Document and Entity Information
Employee and Nonemployee Stock Option [Member]
Stock options
Represents information pertaining to the stock options allotted to employees and non-employees.
Increase (Decrease) in Accrued Liabilities and Other Liabilities
Accrued expenses and other liabilities
The increase (decrease) during the reporting period in the aggregate amount of expenses incurred but not yet paid and other liabilities used in operating activities not separately disclosed.
Noncash Consulting Expense
Noncash consulting expense
Represents the amount of consulting expense included in net income that resulted in no cash outflows or inflows in the period and is not separately disclosed.
Preferred Stock Subscription [Member]
Preferred Stock Subscription
Represents information pertaining to the new issue of securities classified as temporary equity which are allocated to the investors. When securities are sold on a subscription basis, the issuer does not initially receive the total proceeds.
Stock Incentive excluding Plan 2010 [Member]
Outside of the Plan
Represents information pertaining to the outside of the 2010 Stock Incentive Plan.
Revenue Recognition Milestone Method Number of Future Milestones to be Met
Number of future milestones to be met
Represents the number of future milestones to be met for recognition of revenue as per milestone method of revenue recognition.
Temporary Equity Subscriptions and Carrying Amount Attributable to Parent
Total convertible preferred stock
Represents the aggregate amount of securities classified as temporary equity that have been allocated to investors to buy as well as carrying amount, attributable to parent, of an entity's issued and outstanding stock which is not included within permanent equity. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable.
Royalty and Sublicense Payment
Royalty and Sublicense payment
Represent total amount of royalty payments made under contractual arrangement on product sale or sublicense income, up to predetermined maximum.
Operating Leases Allowance for Improvements
Allowance for improvements
Represents the amount of operating lease that provides the company with an allowance for the improvement.
Amount of operating lease for which allowance for improvements is provided
Represents the amount of operating lease for which allowance for improvements is provided during the period.
Amount of Operating Lease for which Allowance for Improvements is Provided
Annual Interest Rate
Annual interest rate (as a percent)
Represents the operating lease annual interest rate.
Security Deposit which May be Reduced in Future
Security deposit in the form of a letter of credit which may be reduced in January 2018.
Represents the amount of an asset, typically cash, provided to a counterparty to provide certain assurance of performance by the entity pursuant to the terms of a written or oral agreement, such as a lease which maybe reduced in future.
Operating Lease Scheduled Rent Payments Due
Scheduled rent payments due
Represents the amount of operating lease scheduled rent payments due during the period.
Increase (Decrease) in Deferred Rent
Deferred rent
The Increase (decrease) during the reporting period in the amount due that is the result of cumulative difference between the payments required by a lease agreement and the rental income or expense recognized on a straight-line basis, or other systematic and rational basis more representative of the time pattern in which use or benefit is granted or derived from the leased property.
Employee Stock Purchase PIan [Member]
ESPP
Represents information pertaining to employee stock purchase plan.
Entity Well-known Seasoned Issuer
Share Based Compensation Arrangement by Share Based Payment Award Offering Period
Offering period
Represents the offering period of awards under the share based compensation plan.
Entity Voluntary Filers
Share Based Compensation Arrangement by Share Based Payment Award Number of Purchase Period
Number of purchase period
Represents the number of purchase period for awards under the share based compensation plan.
Entity Current Reporting Status
Share Based Compensation Arrangement by Share Based Payment Award Purchase Period
Purchase period
Represents the purchase period of awards under the share based compensation plan.
Entity Filer Category
Lessee Leasing Arrangements Operating Leases Number of Additional Lease Term
Number of additional lease term
Represents the number of additional term for which lease can be extend.
Entity Public Float
Lessee Leasing Arrangements Operating Leases Additional Extension Term
Additional extension term of lease
Represents the additional term for which lease can be extend under the lessee's leasing arrangement.
Entity Registrant Name
Entity Central Index Key
Entity Common Stock, Shares Outstanding
Document Fiscal Year Focus
Document Fiscal Period Focus
Legal Entity [Axis]
Document Type
Summary of Significant Accounting Policies
Accrued Expenses
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accounts payable (NPM restricted December 31, 2012 $499)
Accounts Payable, Current
Accounts payable (in dollars)
Accounts payable
Accrued Expenses
Total Accrued Expenses
Accrued Liabilities, Current
Accrued expenses (NPM restricted December 31, 2012 $312)
Accrued expenses
Accrued expenses and other liabilities
Professional fees
Accrued Professional Fees, Current
Less accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated Deficit during Development Stage [Member]
Deficit Accumulated During the Development Stage
Additional paid-in capital
Additional Paid in Capital
Additional Paid-in Capital [Member]
Additional Paid-In Capital
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Stock-based compensation expense
Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition
Proceeds from sale of restricted stock to advisors
Adjustments to Additional Paid in Capital, Share-based Compensation, Restricted Stock Unit or Restricted Stock Award, Requisite Service Period Recognition
Total
Allocated Share-based Compensation Expense
Total expense
Antidilutive Securities [Axis]
Net loss per share
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Net Loss Per Share
Antidilutive Securities, Name [Domain]
Amounts excluded from the calculation of diluted weighted- average shares outstanding, prior to the use of the treasury stock method, due to anti-dilutive effect (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Amounts of potentially dilutive securities that excluded from the calculation of diluted net loss per share due to their anti-dilutive effect (in shares)
Total assets
Assets
Current assets:
Assets, Current [Abstract]
Assets:
Assets
Assets [Abstract]
Total current assets
Assets, Current
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Cash and cash equivalents (NPM restricted December 31, 2012 $12)
Cash and cash equivalents (in dollars)
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period
Cash and Cash Equivalents, at Carrying Value
Cash and Cash Equivalents
Cash and cash equivalents
Cash and Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Money Market Funds, included in cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Supplemental disclosure of non-cash financing activity
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Class of Stock [Line Items]
Stockholders' Equity
Class of Stock [Domain]
Commitments and Contingencies.
Commitments and contingencies (Note 8)
Commitments and Contingencies
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share
Common Stock [Member]
Common Shares
Common Stock
Common stock, $0.0001 par value; 100,000,000 shares authorized; 29,720,422 and 29,587,258 shares issued and outstanding at June 30, 2014 and December 31, 2013, respectively
Common Stock, Value, Issued
Common stock, shares issued
Common Stock, Shares, Issued
Common stock, shares authorized
Common Stock, Shares Authorized
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Significant components of the Company's deferred tax assets
Components of Deferred Tax Assets [Abstract]
Components of income (loss) before income taxes
Components of Income Tax Expense (Benefit), Continuing Operations [Abstract]
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Basis of Consolidation
Consolidation, Policy [Policy Text Block]
Consolidation, Less than Wholly Owned Subsidiary, Parent Ownership Interest, Changes, Purchase of Interest by Parent
Construction in process
Construction in Progress [Member]
Conversion of Stock, Amount Converted
Conversion of convertible preferred stock upon initial public offering
Convertible preferred stock
Convertible Preferred Stock [Member]
Debt Conversion, Original Debt, Amount
Amount of convertible notes converted into Series A Preferred Stock
Debt Instrument, Convertible, Beneficial Conversion Feature
Beneficial conversion feature
Conversion of notes payable to preferred stock
Debt Conversion, Converted Instrument, Amount
Deduction for option exercises
Deferred Tax Expense from Stock Options Exercised
Deferred Rent Credit, Noncurrent
Deferred rent
Deferred Revenue, Current
Deferred revenue
Deferred Rent Credit, Current
Deferred rent
Total deferred tax assets
Deferred Tax Assets, Gross
Research and development credits
Deferred Tax Assets, Tax Credit Carryforwards, Research
Deferred tax assets:
Deferred Tax Assets, Net [Abstract]
Foreign net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Foreign
Less valuation allowance
Deferred Tax Assets, Valuation Allowance
Depreciation and amortization expense
Depreciation
Depreciation and amortization
Depreciation, Depletion and Amortization, Nonproduction
Number of freestanding derivative instruments
Derivative, Number of Instruments Held
Accumulated deficit
Development Stage Enterprise, Deficit Accumulated During Development Stage
Accumulated deficit since inception
Stock-based Compensation
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
Stock-based Compensation
Accounts payable or accrued expenses
Due to Related Parties, Current
Net loss per share applicable to common stockholders-basic and diluted (in dollars per share)
Earnings Per Share, Basic and Diluted
Net loss per share applicable to common stockholders basic and diluted (in dollars per share)
Net Loss Per Share
Earnings Per Share [Text Block]
Net Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Share
Effective income tax rate (as a percent)
Effective Income Tax Rate Reconciliation, Percent
Reconciliation of income tax expense computed at the statutory federal income tax rate to income taxes
Effective Income Tax Rate Reconciliation, Percent [Abstract]
State income tax, net of federal benefit (as a percent)
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Permanent differences (as a percent)
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Other (as a percent)
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Change in valuation allowance (as a percent)
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Federal income tax expense at statutory rate (as a percent)
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Research and development credit (as a percent)
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Foreign rate differential (as a percent)
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Payroll and employee-related costs
Employee-related Liabilities, Current
Total stock-based compensation expense recognized in connection with all share-based payment awards
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total unrecognized stock-based compensation expense related to unvested restricted stock
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Share-based Awards Other than Options
Total unrecognized stock-based compensation expense
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition
Weighted average period for recognition of unrecognized expense
Period for recognition of unrecognized expense
Total unrecognized stock-based compensation expense related to unvested stock options
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options
Laboratory equipment
Equipment [Member]
Equity Component [Domain]
Total
Estimate of Fair Value Measurement [Member]
Measurement Frequency [Axis]
Fair Value Measurements, Recurring and Nonrecurring [Table]
Fair Value, Hierarchy [Axis]
Recurring
Fair Value, Measurements, Recurring [Member]
Fair Value, Measurement Frequency [Domain]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of financial instruments
Fair Value of Financial Instruments
Fair Value Hierarchy [Domain]
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Fair Value of Financial Instruments
Schedule of financial assets measured at fair value and indicates the fair value hierarchy of the valuation inputs utilized to determine such fair value
Fair Value, by Balance Sheet Grouping [Table Text Block]
Level 1
Fair Value, Inputs, Level 1 [Member]
Quoted prices in active markets (Level 1)
Level 2
Fair Value, Inputs, Level 2 [Member]
Significant other observable inputs (Level 2)
U.S.
Federal Income Tax Expense (Benefit), Continuing Operations
Financial assets
Financial Instruments, Financial Assets, Balance Sheet Groupings [Abstract]
Foreign
Foreign Income Tax Expense (Benefit), Continuing Operations
Canadian
Foreign Tax Authority [Member]
Furniture and fixtures
Furniture and Fixtures [Member]
General and administrative
General and Administrative Expense
General and administrative
General and Administrative Expense [Member]
Long-Lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Income Statement Location [Axis]
Income Taxes
Income Tax Authority [Domain]
Income Tax Authority [Axis]
Income Taxes
Income Tax Disclosure [Text Block]
Income Statement Location [Domain]
Totals
Income Tax Expense (Benefit)
Income Taxes
Income Tax, Policy [Policy Text Block]
Deposits
Increase (Decrease) in Deposit Assets
Increase in restricted cash
Increase in Restricted Cash
Accounts payable
Increase (Decrease) in Accounts Payable
Other non-current assets
Increase (Decrease) in Other Noncurrent Assets
Deferred revenue
Increase (Decrease) in Deferred Revenue
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity
Interest expense
Interest Expense
U.S. federal
Federal
Internal Revenue Service (IRS) [Member]
Interest income
Investment Income, Interest
Term of lease
Lessee Leasing Arrangements, Operating Leases, Term of Contract
Optional term to renew the lease
Lessee Leasing Arrangements, Operating Leases, Renewal Term
Leasehold improvements
Leasehold Improvements [Member]
Total current liabilities
Liabilities, Current
Total liabilities and stockholders' equity
Liabilities and Equity
Current liabilities:
Liabilities, Current [Abstract]
Liabilities:
Total Liabilities
Liabilities
Liabilities and stockholders' equity
Liabilities and Equity [Abstract]
Maximum
Maximum [Member]
Minimum
Minimum [Member]
Financing activities
Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract]
Operating activities
Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract]
Net (decrease) increase in cash and cash equivalents
Net Cash Provided by (Used in) Continuing Operations
Net loss
Net Income (Loss) Available to Common Stockholders, Basic
Net loss
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities, Continuing Operations
Net cash (used in) provided by financing activities
Net Cash Provided by (Used in) Financing Activities, Continuing Operations
Net cash used in investing activities
Net Cash Provided by (Used in) Investing Activities, Continuing Operations
Investing activities
Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract]
Recently Issued Accounting Pronouncements
Recently Issued Accounting Pronouncements
New Accounting Pronouncements and Changes in Accounting Principles [Text Block]
Interest income
Nonoperating Income (Expense)
Other income (expense):
Nonoperating Income (Expense) [Abstract]
Issuance of convertible notes in satisfaction of accrued expenses
Notes Issued
Number of operating segments
Number of Operating Segments
Office and computer equipment
Office Equipment [Member]
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
Minimum future rent payments under the lease agreement
Operating expenses:
Operating Expenses [Abstract]
Total operating expenses
Operating Expenses
Total operating expenses
Total rent expense
Operating Leases, Rent Expense, Net
Operating Leases, Future Minimum Payments Due, Next Twelve Months
2014
Loss from operations
Operating Income (Loss)
Maximum rent until which base rent rises periodically
Operating Leases, Rent Expense, Contingent Rentals
Operating Loss Carryforwards [Table]
Income Taxes
Operating Loss Carryforwards [Line Items]
Operating Leases, Future Minimum Payments, Due in Two Years
2015
Initial annual base rent
Operating Leases, Rent Expense, Minimum Rentals
Total future minimum lease payments
Operating Leases, Future Minimum Payments Due
Net operating loss carryforwards
Operating Loss Carryforwards
Organization and Operations
Organization and Operations
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Other assets
Other Assets, Noncurrent
Total other income (expense)
Other Nonoperating Income (Expense)
Total other income (expense)
Other long-term liabilities
Other Liabilities, Noncurrent
Other current liabilities
Other Liabilities, Current
Other
Other Accrued Liabilities, Current
Noncash interest expense
Paid-in-Kind Interest
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Issuance costs from the sale of common stock
Payments of Stock Issuance Costs
Plan Name [Domain]
Plan Name [Axis]
Convertible preferred stock, par value (in dollars per share)
Preferred Stock, Par or Stated Value Per Share
Convertible preferred stock, $0.0001 par value; 5,000,000 shares authorized; none issued and outstanding
Preferred Stock, Value, Issued
Convertible preferred stock, shares issued
Preferred Stock, Shares Issued
Convertible preferred stock, shares authorized
Preferred Stock, Shares Authorized
Convertible preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Preferred stock financings
Preferred Stock [Member]
Prepaid Expenses and other current assets
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets (NPM restricted December 31, 2012 $485)
Prepaid expenses and other current assets
Proceeds from Convertible Debt
Proceeds from the issuance of convertible notes
Proceeds from the issuance of preferred stock subscription
Proceeds from Issuance of Preferred Stock and Preference Stock
Proceeds from Issuance Initial Public Offering
Net proceeds from public offering
Net proceeds from issuance of common stock
Proceeds from Issuance of Common Stock
Proceeds from the exercise of stock options
Proceeds from Stock Options Exercised
Estimated useful life
Property, Plant and Equipment, Useful Life
Property, Plant and Equipment, Gross
Property and equipment, gross
Property and Equipment, net
Property, Plant and Equipment, Policy [Policy Text Block]
Property and equipment, net
Property, Plant and Equipment, Net
Property and equipment, net
Property and Equipment, net
Property, Plant and Equipment, Type [Domain]
Property, Plant and Equipment, Type [Axis]
Property and Equipment, net
Property, Plant and Equipment Disclosure [Text Block]
Property and equipment, net
Property, Plant and Equipment [Line Items]
Property and Equipment, net
Selected Quarterly Financial Information (Unaudited)
Quarterly Financial Information [Text Block]
Selected Quarterly Financial Information (Unaudited)
Range [Axis]
Range [Domain]
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Expenses for consulting and contract research services
Related Party Transaction, Expenses from Transactions with Related Party
Related Party Transactions
Principal payments of convertible notes
Repayments of Convertible Debt
Research and development
Research and Development Expense
Research and development
Research and Development Expense [Member]
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Research and development tax credit carryforwards
Research Tax Credit Carryforward [Member]
Research Agreements
Research Agreements
Research, Development, and Computer Software Disclosure [Text Block]
Unvested restricted stock
Restricted Stock [Member]
Non-vested restricted stock
Restricted cash
Restricted Cash and Cash Equivalents, Noncurrent
Revenue Recognition
Revenue Recognition, Policy [Policy Text Block]
Amount recognized
Revenue Recognition, Milestone Method, Revenue Recognized
Revenue Recognition
Revenue Recognition, Milestone Method [Line Items]
Revenue Recognition, Milestone Method [Table]
Unvested at the beginning of the period (in shares)
Unvested at the end of the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares
Vesting percentage
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value
Options exercisable at the end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term
Expected term
Purchase price of common stock (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent
Expiration period
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Options vested or expected to vest at the end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Options exercisable at the end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Outstanding at the end of the period
Contract and grant revenue
Revenue, Net
Revenue
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of assets and liabilities measured at fair value on a recurring basis
Schedule of financial instruments measured at fair value based on the three fair value hierarchy tiers
Schedule of amounts excluded from the calculation of diluted weighted-average shares outstanding , prior to the use of the treasury stock method, due to anti-dilutive effect
Schedule of potentially dilutive securities that were excluded from the calculation of diluted net loss per share due to their anti-dilutive effect
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Summary of unvested restricted stock
Schedule of Nonvested Share Activity [Table Text Block]
Summary of stock option activity and related information
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]
Schedule of assumptions used to estimate fair value of each employee and non-employee stock award on the grant date using the Black Scholes option pricing model
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Schedule of components of income (loss) before income taxes
Schedule of assets and liabilities reflected on the Company's balance sheet
Condensed Balance Sheet [Table Text Block]
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of reconciliation of income tax expense computed at the statutory federal income tax rate to income taxes
Schedule of significant components of the Company's deferred tax assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of accrued expenses
Schedule of Accrued Liabilities [Table Text Block]
Schedule of minimum future rent payments under the lease agreement
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]
Schedule of selected quarterly financial information
Schedule of Quarterly Financial Information [Table Text Block]
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table]
Schedule of total stock-based compensation expense recognized in connection with all share-based payment awards
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]
Property, Plant and Equipment [Table]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Stock by Class [Table]
Security deposit in the form of a letter of credit
Security Deposit
Segment Information
Segment Reporting, Policy [Policy Text Block]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted-average price
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted (in shares)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Canceled (in dollars per share)
Non-vested at the beginning of the period (in shares)
Non-vested at the end of the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of non-vested shares
Number of additional shares available under the 2013 plan
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized
Vested (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period
Share-based Compensation
Stock-based compensation expense
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted-average purchase price
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Granted (in shares)
Stock-based compensation
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Unvested at the end of the period (in dollars per share)
Unvested at the beginning of the period (in dollars per share)
Public offering price of common shares (in dollars per share)
Share Price
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Weighted Average Volatility Rate
Volatility (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Options exercisable at the end of the period (in dollars per share)
Dividend (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Aggregate fair value of restricted stock awards vested
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period
Canceled (in shares)
Vested (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Aggregate fair value of restricted stock awards vested (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number
Options exercisable at the end of the period (in shares)
Number of shares available for issuance under the Plan
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Total intrinsic value of stock options exercised
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value
Number of shares of Common Stock reserved for issuance under the Plan
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized
Number of shares of common stock authorized (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Assumptions used to estimate fair value of each employee and non-employee stock award on the grant date using the Black Scholes option pricing model
Weighted-average grant date fair values of options granted (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Outstanding at the beginning of the period (in dollars per share)
Outstanding at the end of the period (in dollars per share)
Accounting for Stock-Based Compensation
Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block]
Outstanding at the beginning of the period (in shares)
Outstanding at the end of the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Options vested or expected to vest at the end of the period (in shares)
Outstanding at the end of the period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Shares
Equity Award [Domain]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Options vested or expected to vest at the end of the period (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Options vested or expected to vest at the end of the period
Shares, Issued
Balance (in shares)
Balance (in shares)
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
U.S. state
State
State and Local Jurisdiction [Member]
Statement [Table]
Statement
Statement [Line Items]
Consolidated Statements Of Convertible Preferred Stock And Stockholders' Equity (Deficit)
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
Equity Components [Axis]
CONDENSED CONSOLIDATED BALANCE SHEETS
Assets and liabilities reflected on the Company's balance sheet
Class of Stock [Axis]
Stock Issued During Period, Shares, Issued for Services
Issuance of common stock in connection with a service agreement (in shares)
Number of common stock issued in connection with service contract
Vesting of restricted stock
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures
Vesting of restricted stock (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Stock Issued During Period, Value, Stock Options Exercised
Exercise of stock options
Stock Issued During Period, Value, Issued for Services
Aggregate cash consideration for number of shares of common stock sold in connection with service contract
Conversion of notes payable into Series A convertible preferred stock
Stock Issued During Period, Value, Conversion of Convertible Securities, Net of Adjustments
Value of shares issued upon conversion of notes payable into Series A convertible preferred stock
Issuance of shares related to preferred stock subscription
Stock Issued
Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures
Issuance of non-vested restricted stock pursuant to the exercise of stock options prior to vesting
Stock Repurchase Program, Number of Shares Authorized to be Repurchased
Number of shares authorized under stock purchase agreement
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Exercised (in shares)
Exercise of Stock Options (in shares)
Exercise of stock options (in shares)
Shares of common stock issued (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Stock Issued During Period, Shares, New Issues
Number of shares of common stock sold in public offering
Outstanding stock options
Equity Option [Member]
Number of shares of common stock issued upon automatic conversion of outstanding convertible preferred stock
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of notes payable into Series A convertible preferred stock (in shares)
Number of shares of stock issued upon automatic conversion of outstanding convertible securities
Aggregate cash consideration for number of shares of common stock sold
Stock Issued During Period, Value, New Issues
Initial public offering, net of issuance costs of $3,207
Stockholders' equity
Stockholders' Equity Attributable to Parent [Abstract]
Total stockholders' equity
Stockholders' Equity Attributable to Parent
Balance
Balance
Stockholders' Equity
Stockholders' Equity
Stockholders' Equity Note Disclosure [Text Block]
Reverse stock split ratio of the common stock
Stockholders' Equity Note, Stock Split, Conversion Ratio
Subsequent Events
Subsequent Events [Text Block]
Subsequent Events
Subsequent Event [Table]
Subsequent Event [Line Items]
Subsequent Events
Subsequent Events
Subsequent Events, Policy [Policy Text Block]
Subsequent Event [Member]
Subsequent events
Subsequent Event Type [Domain]
Subsequent Event Type [Axis]
Tax credit carryforwards
Tax Credit Carryforward, Amount
Tax Credit Carryforward, Name [Domain]
Income Taxes
Tax Credit Carryforward [Line Items]
Tax Credit Carryforward [Table]
Tax Credit Carryforward [Axis]
Convertible preferred stock, outstanding shares
Temporary Equity, Shares Outstanding
Preferred stock, outstanding shares
Convertible preferred stock, par value (in dollars per share)
Temporary Equity, Par or Stated Value Per Share
Convertible preferred stock
Temporary Equity, Carrying Amount, Attributable to Parent
Schedule of convertible preferred stock
Temporary Equity [Table Text Block]
Convertible preferred stock, authorized shares
Temporary Equity, Shares Authorized
Convertible preferred stock, issued shares
Temporary Equity, Shares Issued
Title of Individual [Axis]
Relationship to Entity [Domain]
Type of Arrangement and Non-arrangement Transactions [Axis]
Interest or penalties related to uncertain tax positions recognized in statements of operations and comprehensive loss
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Accrued interest or penalties related to uncertain tax positions
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Vesting [Axis]
Vesting [Domain]
Increase in valuation allowance
Valuation Allowance, Deferred Tax Asset, Change in Amount
Variable Interest Entity, Primary Beneficiary [Member]
NPM
Ownership percentage (as a percent)
Variable Interest Entity, Qualitative or Quantitative Information, Ownership Percentage
Weighted-average number of common shares outstanding used in net loss per share applicable to common stockholders-basic and diluted (in shares)
Weighted Average Number of Shares Outstanding, Basic and Diluted