Document Document And Entity Information [Abstract]. Document Document And Entity Information [Abstract] Statement [Table] Statement [Line Items] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Balance Sheets [Abstract] Assets [Abstract] Assets Assets Current [Abstract] Current assets: Cash And Cash Equivalents At Carrying Value Cash and cash equivalents, end of period Cash and cash equivalents, beginning of period Cash and cash equivalents Available-for-sale Securities, Current Short-term investments, available-for-sale Estimated fair value Accounts Receivable, Net, Current Accounts receivable Prepaid Expense and Other Assets, Current Prepaid and other current assets Deferred Costs, Current Deferred financing costs, current portion Assets Current Total current assets Property Plant And Equipment Net Property and equipment, net of accumulated depreciation Deposits Assets, Noncurrent Deposits Deferred Costs, Noncurrent Deferred financing costs, less current portion Assets Total assets Liabilities And Stockholders Equity [Abstract] Liabilities, redeemable convertible preferred stock and stockholders' deficit Liabilities Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued liabilities Loans Payable, Current Loan payable, current portion Liabilities Current Total current liabilities Other Liabilities, Noncurrent Other long-term liabilities Loans Payable Noncurrent Loans Payable Noncurrent Loan payable, less current portion Liabilities Total liabilities Commitments and Contingencies Commitments and contingencies Stockholders Equity Including Portion Attributable To Noncontrolling Interest [Abstract] Stockholders' equity: Preferred Stock, Value, Outstanding Preferred stock, $0.001 par value, 10,000,000 shares authorized at June 30, 2014 and December 31, 2013; no shares issued and outstanding as of June 30, 2014 and December 31, 2013 Common Stock Value Common stock, $0.001 par value, 200,000,000 shares authorized at June 30, 2014 and December 31, 2013; 35,404,326 and 26,664,972 shares issued and outstanding as of June 30, 2014 and December 31, 2013, respectively Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income Loss Net Of Tax Accumulated other comprehensive loss Retained Earnings Accumulated Deficit Accumulated deficit Stockholders Equity Total stockholders' equity Liabilities And Stockholders Equity Total liabilities and stockholders' equity Preferred Stock Par Or Stated Value Per Share Preferred stock, par value Preferred Stock Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock Par Or Stated Value Per Share Common stock, par value Common Stock Shares Authorized Common stock, shares authorized Common Stock Shares Issued Common stock, shares issued Common Stock Shares Outstanding Common stock, shares outstanding Statements Of Operations And Comprehensive Loss [Abstract] Revenues: Contracts Revenue Contract revenue Revenues Total revenues Operating expenses: Research and Development Expense Research and development Selling General And Administrative Expense General and administrative Operating Income Loss Loss from operations Other expense: Interest Expense Interest expense, net Interest expense Fair value adjustments to warrant liability Fair value adjustments to warrant liability Fair value adjustments to warrant liability Fair value measurement of redeemable convertible preferred stock warrant liability Profit Loss Net loss Net loss Other comprehensive loss: Available-for-sale Securities, Gross Realized Gain (Loss) Unrealized gain (loss) on securities available-for-sale Other Comprehensive Income Loss Net Of Tax Comprehensive loss Preferred Stock, Accretion of Redemption Discount Accretion of redeemable convertible preferred stock Net Income (Loss) Attributable to Parent Net loss attributable to common shareholders Per share information: Earnings Per Share, Basic and Diluted Net loss per common share, basic and diluted Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted-average shares outstanding, basic and diluted Statements Of Cash Flows [Abstract] Net Cash Provided By Used In Operating Activities [Abstract] Operating activities Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation Amortization of Financing Costs Non-cash interest expense Accretion (Amortization) of Discounts and Premiums, Investments Amortization/accretion of premium/discount on investments Share Based Compensation Share-based compensation costs Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Accounts Receivable Accounts receivable Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets and deposits Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts payable and accrued liabilities Net Cash Provided By Used In Operating Activities Net cash used in operating activities Net Cash Provided By Used In Investing Activities [Abstract] Investing activities: Payments to Acquire Property, Plant, and Equipment Purchase of property and equipment Payments to Acquire Short-term Investments Purchase of short-term investments Proceeds from Maturities, Prepayments and Calls of Short-term Investments Maturities of short-term investments Net Cash Provided By Used In Investing Activities Net cash (used in) provided by investing activities Net Cash Provided By Used In Financing Activities [Abstract] Financing activities: Proceeds From Stock Options Exercised Proceeds from exercise of stock options Proceeds from Stock Plans Proceeds from employee stock purchase plan issuance Proceeds from Issuance of Warrants Proceeds from exercise of warrant Proceeds from Issuance of Common Stock Proceeds from public offering, net of offering costs Line of Credit Facility, Decrease, Repayments Repayment of loan payable Net Cash Provided By Used In Financing Activities Net cash provided by financing activities Cash And Cash Equivalents Period Increase Decrease Increase in cash and cash equivalents Supplemental cash flow information: Interest Paid, Net Interest payments The Business and Summary of Significant Accounting Policies [Abstract] Basis Of Presentation And Significant Accounting Policies [Text Block] The Business and Summary of Significant Accounting Policies Investments [Abstract] Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Investments Loan Payable [Abstract] Debt Disclosure [Text Block] Loan Payable Commitments and Contingencies [Abstract] Commitments And Contingencies Disclosure [Text Block] Commitments and Contingencies Equity and Share Based Compensation [Abstract]. Equity and Share Based Compensation [Abstract] The entire disclosure related to equity and share based compensation. Equity And Share Based Compensation [Text Block] Equity and Share Based Compensation Income Taxes [Abstract] Income Tax Disclosure [Text Block] Income Taxes The entire disclosure related to significant agreements. Significant Agreements [Abstract] Significant Agreements [TextBlock]. Significant Agreements [Text Block] Significant Agreements Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Description of Business Use of Estimates, Policy [Policy Text Block] Use of Estimates Fair Value Of Financial Instruments Policy Fair Value of Financial Instruments Revenue Recognition, Policy [Policy Text Block] Revenue Recognition The entire policy related to clinical trial accruals. Clinical Trial Accruals [Policy Text Block] Clinical Trial Accruals/Prepaids Earnings Per Share, Policy [Policy Text Block] Basic and Diluted Net Loss Per Common Share Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block] Assets and Liabilities Measured at Fair Value on a Recurring Basis Available-for-sale Securities [Table Text Block] Summary of Available-for-Sale Securities Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] Schedule of Warrants Issued, Outstanding and Exercisable Fair value of options vested and share-based compensation expense recognized Schedule of Share-Based Compensation Expense Statement Class Of Stock [Axis] Class Of Stock [Domain] Class of Stock [Domain] Series F Preferred Stock [Member] Series F [Member] Warrant [Member] Warrant [Member] Statement Scenario [Axis] Scenario Unspecified [Domain] Scenario, Unspecified [Domain] Over Allotment Option [Member] Over Allotment Options [Member] Description Of Business [Abstract]. Description Of Business Stockholders' Equity, Reverse Stock Split Stock split, reverse description Stockholders' Equity Note, Stock Split, Conversion Ratio Reverse stock split, conversion ratio Stock Issued During Period, Shares, New Issues Stock issued during the period, shares Stock Issued During Period, Value, New Issues Stock issued during the period, value Shares issued, price per share The initial stock price of the public offering. Public Offering Intital Stock Price Stock price, public offering Proceeds from Issuance Initial Public Offering Proceeds from public offering Public offering underwriting discounts and commissions. Public Offering Underwriting Discounts And Commissions Public offering underwriting discounts and commissions Payments of Stock Issuance Costs Offering expenses Conversion of Stock, Shares Converted Conversion of stock, shares converted Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Anti-dilutive securities excluded from the calculation loss per share Schedule of Fair Value of Separate Accounts by Major Category of Investment [Table] Asset Class [Axis] Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation By Asset Class [Domain] Asset Class [Domain] Cash And Cash Equivalents [Member] Cash and Cash Equivalents [Member] Short Term Investments [Member] Short-term Investments [Member] Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value, Measurements, Fair Value Hierarchy [Domain] Fair Value Inputs Level1 [Member] Quoted Prices in Active Markets for Identical Assets (Level 1) [Member] Fair Value Inputs Level2 [Member] Significant Other Observable Inputs (Level 2) [Member] Fair Value Inputs Level3 [Member] Significant Unobservable Inputs (Level 3) [Member] Schedule of Fair Value of Separate Accounts by Major Category of Investment [Line Items] Assets, Fair Value Disclosure Assets, fair value Schedule of Investments [Table] Investment Type [Axis] Investment Type Categorization [Member] Investments [Domain] Corporate Note Securities [Member] Corporate Bonds [Member] Commercial Paper [Member] Commercial Paper [Member] Bank Time Deposits [Member] Bank Time Deposits [Member] Certificates Of Deposit [Member] Certificates of Deposit [Member] Schedule of Investments [Line Items] Available-for-sale Securities, Amortized Cost Basis Amortized cost Available-for-sale Securities, Gross Unrealized Gains Gross unrealized gains Available-for-sale Securities, Gross Unrealized Losses Gross unrealized losses Investment maturity period, maximum. Investment Maturity Period Maximum Investments maturity period, maximum Line of Credit Facility [Table] Debt Instrument [Axis] Debt Instrument Name [Domain] Debt Instrument, Name [Domain] Second Tranche [Member]. Second Tranche [Member] Second Tranche [Member] First Tranche [Member]. First Tranche [Member] First Tranche [Member] Loan And Security Agreement [Member] Loan And Security Agreement [Member] Loan and Security Agreement [Member] Line of Credit Facility [Line Items] Line of Credit Facility, Maximum Borrowing Capacity Loan and security agreement, maximum capacity Line of Credit Facility, Amount Outstanding Loan and security agreement, outstanding Line of Credit Facility, Remaining Borrowing Capacity Loan and security agreement, remaining capacity Payments for Loans Loan payment Deferred Finance Costs, Current, Gross Deferred financing costs Interest only period. Interest Only Period Interest only period Principal and interest amortization period. Principal And Interest Amortization Period Principal and interest amortization period Line of Credit Facility, Interest Rate During Period Loan and security agreement, interest rate Class of Warrant or Right, Exercise Price of Warrants or Rights Preferred stock, strike price Warrants exercise price Class of Warrant or Right, Number of Securities Called by Warrants or Rights Warrants to purchase common stock Operating Leases, Rent Expense, Net Operating leases, rent expense Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] The 2013 Plan [Member] The2013 Plan [Member] The 2013 Plan [Member] Employee Stock Ownership Plan (ESOP) Name [Axis] Employee Stock Ownership Plan E S O P Plan [Domain] Employee Stock Ownership Plan (ESOP), Plan [Domain] The 2013 Employee Stock Purchase Plan Member. The2013 Employee Stock Purchase Plan [Member] 2013 Employee Stock Purchase Plan [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Number of warrants to purchase common stock that converted from warrants to purchase redeemable convertible preferred stock during IPO Warrants Issued During Period Shares Preferred Stock And Warrants Redeemable convertible preferred stock, warrants issued Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Number of shares authorized to be granted Fair Value Adjustment of Warrants Fair value adjustment of warrants Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Number of shares outstanding under the plan Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized Additional shares authorized Common Stock, Capital Shares Reserved for Future Issuance Shares available for issuance