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Disclosure - Inventory link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - Property, Plant and Equipment link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - Accrued Expenses and Other Current Liabilities link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - Warrants and Warrant Derivative Liability link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - Debt link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - Commitments and Contingencies link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - Equity link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Income Taxes link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Stock Incentive Plans and Stock Based Compensation link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - Defined Contribution Plan link:calculationLink link:presentationLink link:definitionLink 121 - 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Disclosure - Components of Loss from Operations Before Taxes (Detail) link:calculationLink link:presentationLink link:definitionLink 162 - Disclosure - Benefit from Income Taxes (Detail) link:calculationLink link:presentationLink link:definitionLink 163 - Disclosure - Difference between Benefit from Income Taxes and Amount Computed by Applying Statutory Income Tax Rate to Income Before Taxes (Detail) link:calculationLink link:presentationLink link:definitionLink 164 - Disclosure - Income Taxes Effect of Each Type of Temporary Difference Comprising Net Differed Tax Asset (Detail) link:calculationLink link:presentationLink link:definitionLink 165 - Disclosure - Valuation Allowance (Detail) link:calculationLink link:presentationLink link:definitionLink 166 - Disclosure - Stock Incentive Plans and Stock Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 167 - Disclosure - Stock Option Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 168 - 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Development, Commercialization and Supply Agreement - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink