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<!-- Creation Date      : 2016-03-12T14:35:49.8639289+00:00 -->
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<!-- Copyright (c) 2016 R. R. Donnelley & Sons Company. All Rights Reserved. -->
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  <element id="akba_OperatingLeasePaymentsCommencementDate" name="OperatingLeasePaymentsCommencementDate" type="xbrli:dateItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <element id="akba_CapitalLeaseTerm" name="CapitalLeaseTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <element id="akba_CapitalLeaseCommencementDate" name="CapitalLeaseCommencementDate" type="xbrli:gYearMonthItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <element id="akba_PurchaseCommittedProgramAmountNotYetPaid" name="PurchaseCommittedProgramAmountNotYetPaid" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <element id="akba_DefinedContributionPlanEmployeesAgeToBeEligibleUnderPlan" name="DefinedContributionPlanEmployeesAgeToBeEligibleUnderPlan" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
</schema>


