Document and Entity Information [Abstract] Document and Entity Information [Abstract] Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Amendment Flag Amendment Flag Document Type Document Type Document Period End Date Document Period End Date Entity Filer Category Entity Filer Category Balance Sheets [Abstract] Statement of Financial Position [Abstract] Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and cash equivalents at beginning of period Cash and cash equivalents at end of period Grants Receivable, Current Contracts and grants receivable Grants receivable Prepaid Expense, Current Prepaid expenses Assets, Current Total current assets Total current assets Property, Plant and Equipment, Net Office furniture and equipment, net Intangible Assets, Net (Excluding Goodwill) Intangible assets, net Assets Identifiable Assets Total assets Total assets Liabilities and Equity [Abstract] Liabilities and shareholders' deficiency Liabilities and shareholders' equity Liabilities and shareholders' equity (deficiency) Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses Notes Payable, Current Notes payable Derivative Liability, Current Warrant liability Employee-Related Liabilities, Current Accrued compensation Liabilities, Current Total current liabilities Total current liabilities Commitments and Contingencies Commitments and contingencies Stockholders' Equity Attributable To Parent [Abstract] Shareholders' equity deficiency: Shareholders' deficiency: Shareholders' equity (deficiency): Preferred Stock, Value, Issued Preferred stock, 350,000 shares authorized; none issued or outstanding Preferred stock; 250,000 shares authorized; none issued or outstanding Common Stock, Value, Issued Common stock, $.001 par value; 50,000,000 shares authorized; 31,269,522 and 23,936,568 shares issued and outstanding in 2015 and 2014, respectively Common stock, $.001 par value; 5,000,000 shares authorized; 3,126,952 and 2,393,657 shares issued and outstanding in 2015 and 2014, respectively (1) Common stock, $.001 par value; 10,000,000 shares and 5,000,000 shares authorized at September 30, 2016 and December 31, 2015, respectively; 3,754,224 shares and 3,126,952 shares issued and outstanding at September 30, 2016 and December 31, 2015, respectively(1) Additional Paid In Capital Additional paid-in capital(1) Additional paid-in capital Retained Earnings (Accumulated Deficit) Accumulated deficit Total Shareholders' Equity Total shareholders' equity Total shareholders' equity (deficiency) Beginning Balance Ending Balance Liabilities and Equity Total liabilities and shareholders equity Total liabilities and shareholders' equity (deficiency) Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding Statements Of Operations [Abstract] Income Statement [Abstract] Revenues [Abstract] Revenues Contracts Revenue Contract revenue Revenue From Grants Revenues Grant revenue Revenues Contract/Grant Revenue Total revenues Cost Of Revenue Cost of grant revenues Cost of revenues Gross Profit Gross profit Gross profit Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development Research and Development in Process Acquired in-process research and development Issuance of common stock for acquisition of in-process research and development General and Administrative Expense General and administrative Operating Expenses Total operating expenses Total operating expenses Total operating expenses Operating Income (Loss) Loss from Operations Income (Loss) from Operations Loss from operations Nonoperating Income (Expense) [Abstract] Other income (expense): Other income: Fair Value Adjustment of Warrants Less change in fair value of warrant liability Change in fair value of warrant liability Change in fair value of warrant liability Other Income Other income Interest Income (Expense), Net Interest income (expense) Interest income Total other income (expense) Nonoperating Income (Expense) Total other income (expense) Other Income (Expense), Net Total other income (expense) Other Income / (Expense), Net Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Extraordinary Items, Noncontrolling Interest Net loss before income taxes Income Tax Expense (Benefit) Income tax benefit Income tax benefit Income tax benefit Net Income (Loss) Attributable To Parent Net income (loss) Net loss Net loss Net income/(loss) for basic earnings per share Earnings Per Share, Basic Basic net income (loss) per share(1) Basic net income (loss) per share Basic net loss per share Earnings Per Share, Diluted Diluted net loss per share (1) Diluted net loss per share(1) Diluted net loss per share Weighted-average basic common shares outstanding Weighted-average basic common shares outstanding Basic weighted average common shares outstanding(1) Weighted Average Number of Shares Outstanding, Diluted Denominator for diluted earnings per share - adjusted weighted-average shares Diluted weighted average common shares outstanding(1) Denominator for diluted earnings per share - adjusted weighted-average shares Statements Of Changes In Shareholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Statement [Table] Statement [Table] Equity Components [Axis] Statement, Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock [Member] Common Stock Additional Paid-In Capital Additional Paid-In Capital Accumulated Deficit Accumulated Deficit Statement [Line Items] Statement [Line Items] Shares, Outstanding Balance, March 31, 2011 (Shares) Beginning Balance, Shares Ending Balance, Shares Stock Issued During Period, Value, Other Issuance of common stock pursuant to Lincoln Park Equity line Issuance of common stock pursuant to Lincoln Park Equity line Stock Issued During Period, Shares, Other Issuance of common stock pursuant to Lincoln Park Equity line, Shares Issuance Of Common Stock Pursuant To Equity Line Purchase Agreement Equity Line Purchase Issuance of common stock pursuant to Equity Line Purchase Agreement Issuance of common stock pursuant to Equity Line Purchase Agreement. Issuance Of Common Stock Pursuant To Equity Line Purchase Agreement, Share Issuance of common stock pursuant to equity line purchase agreement, shares Issuance of common stock pursuant to Equity Line Purchase Agreement, Shares Issuance of common stock pursuant to Equity Line Purchase Agreement share value. Stock Issuance Cost Associated With Equity Line Purchase Agreement Costs associated with Lincoln Park Equity Line Stock issuance cost associated with Equity Line Purchase Agreement Stock issuance cost associated with Equity Line Purchase Agreement. Stock Issued During Period, Value, New Issues Issuance of common stock Issuance of common stock to SciClone Purchase of common stock Stock Issued During Period, Shares, New Issues Issuance of common stock to SciClone, Shares Issuance of common stock, shares Common stock were issued Stock Issued During Period, Value, Issued for Services Issuance of common stock to vendors Stock Issued During Period, Shares, Issued for Services Common stock issued for vendor services Issuance of common stock as partial consideration for services performed, shares Stock Issued During Period, Value, Stock Options Exercised Issuance of shares from exercise of stock options Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Issuance of common stock from exercise of stock options, shares Issuance of shares from exercise of stock options, Shares Issue of stock option Shares of common stock that remained issuable upon the exercise Exercised Stock Issued During Period Warrants Exercised Value Issuance of shares for exercise of warrants Stock issued during period value warrants exercised. Stock Issued During Period Shares Warrants Exercised Issuance of shares for exercise of warrants, Shares Stock Issued During Period Shares Warrants Exercised. Reclassification Of Warrant Liability Upon Partial Exercise Of Warrants Issued In Unit Offering Reclassification of warrant liability upon partial exercise of warrants issued in unit offering Reclassification of warrant liability upon partial exercise of warrants issued in unit offering. Adjustments To Additional Paid In Capital Warrant Issued To Vendors Fair value of common stock warrants issued to vendors Amount of Fair value of common stock warrants to vendors. Stockholders' Equity, Other Charge for common stock issued for collaboration agreement Issuance of common stock to collaboration partner Stockholders' Equity, Other Shares Issuance of common stock to collaboration partner, Shares Stock Issued During Period, Value, Acquisitions Shares issued in connection with acquisition of in-process research and development Stock Issued During Period, Shares, Acquisitions Shares issued in connection with acquisition of in-process research and development, Shares Common stock issued in connection with Hy BioPharma acquisition of in-process research and development, shares Issuance Of Common Stock From Cashless Exercise Of Warrants Issuance of common stock from cashless exercise of warrants Issuance of common stock from cashless Exercise of warrants. Issuance Of Common Stock From Cashless Exercise Of Warrants Shares Issuance of common stock from cashless exercise of warrants, Shares Issuance of common stock from cashless exercise of warrants,shares Issuance of common stock from cashless exercise of warrants,shares. Adjustments To Additional Paid In Capital, Share-Based Compensation, Requisite Service Period Recognition Share-based compensation expense Stock Issued During Period, Value, Conversion of Units Common stock issued in unit offering Common stock issued in unit offering, net of offering costs of $344,808 Stock Issued During Period, Shares, Conversion of Units Common stock issued in unit offering, net of offering costs of $344,808, Shares Common stock issued in unit offering, shares Other Ownership Interests, Offering Costs Net of offering costs Statements Of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Net Cash Provided By (Used In) Operating Activities [Abstract] Operating activities: Adjustments To Reconcile Net Income (Loss) To Cash Provided By (Used In) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation, Depletion and Amortization Amortization and Depreciation Expense Amortization and depreciation Amortization of Debt Discount (Premium) Amortization discount Amortization of discount on debt Share-based Compensation Share-Based Compensation Share-based compensation Gain On Settlement Liability Gain on settlement liability. Gain on settlement liability Issuance of Stock and Warrants for Services or Claims Common stock issued in exchange for services Issuance of common stock for services Warrants Issued To Vendors Warrants issued to vendors. Warrants issued to vendor Increase (Decrease) In Operating Capital [Abstract] Change in operating assets and liabilities: Increase (Decrease) in Accounts and Other Receivables Contract and Grants receivable Contracts and grants receivable Increase (Decrease) In Prepaid Expense Prepaid expenses Prepaid expenses Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts payable and accrued expenses Increase (Decrease) In Accounts Payable, Trade Accounts payable Increase (Decrease) In Accrued Salaries Accrued compensation Adjustments To Reconcile Net Income (Loss) To Cash Provided By (Used In) Operating Activities Total adjustments Total adjustments Increase (Decrease) In Income Taxes Receivable Taxes receivable Taxes receivable Net Cash Provided By (Used In) Operating Activities, Total Net cash used in operating activities Net cash used in operating activities Net Cash Provided By (Used In) Investing Activities [Abstract] Investing activities: Payments To Acquire Machinery and Equipment Purchases of fixed assets Purchases of office furniture and equipment Payments to Acquire in Process Research and Development Payments for acquisition of in-process research and development Payments for acquisition of in-process research and development Net Cash Provided By (Used In) Investing Activities Net cash used in investing activities Net cash used in investing activities Net Cash Provided By (Used In) Financing Activities [Abstract] Financing activities: Proceeds from Issuance of Common Stock Proceeds from issuance of common stock pursuant to the equity line Net proceeds from issuance of common stock pursuant to the equity lines Stock Issuance Costs Associated With Equity Line Purchase Agreement Stock issuance costs associated with equity line purchase agreement Stock issuance costs associated with equity line purchase agreement. Stock issuance costs associated with equity line purchase agreement Repayments of Notes Payable Repayment of notes payable Proceeds From Issuance Of Common Stock To Sciclone Proceeds from issuance of common stock to sciclone Proceeds from issuance of common stock to sciclone. Proceeds from Warrant Exercises Proceeds from exercise of warrants Proceeds from Stock Options Exercised Proceeds from exercise of stock options Proceeds from Issuance or Sale of Equity Net proceeds from sale of units containing common stock and warrants Net Cash Provided By (Used In) Financing Activities Net cash provided by financing activities Net cash provided by financing activities Cash and Cash Equivalents, Period Increase (Decrease), Total Net increase in cash and cash equivalents Net increase (decrease) in cash and cash equivalents Net decrease in cash and cash equivalents Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non cash financing activities: Additional Paid In Capital, Reclassification Of Warrant Liability Reclassification of warrant liability to additional paid in capital upon partial exercise of warrants issued in unit offering Fair value of the warrants exercised Carrying amount of a reclassification of warrant liability upon partial exercise of warrants issued in unit offering. Notes Payable Issued In Connection With Equity Purchase Agreement Notes payable issued in connection with Equity Purchase Agreement Notes payable issued in connection with Equity Purchase Agreement. Supplemental Cash Flow Elements [Abstract] Supplemental information: Income Taxes Paid Cash paid for state income taxes Nature of Business [Abstract] Nature of Business [Abstract] Nature Of Operations [Text Block] Nature of Business Summary of Significant Accounting Policies [Abstract] Summary of Significant Accounting Policies [Abstract] Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Intangible Assets [Abstract] Intangible Assets [Abstract] Intangible Assets Disclosure [Text Block] Intangible Assets Notes Payable [Abstract] Debt Disclosure [Text Block] Notes Payable Warrant Liability [Abstract] Warrant Liabilities [Text Block] Warrant Liability The entire disclosure for the warrant liabilities. Income Taxes [Abstract] Income Taxes [Abstract] Income Tax Disclosure [Text Block] Income Taxes Shareholders' Deficiency [Abstract] Stockholders Equity Note Disclosure [Text Block] Shareholders' Deficiency Stock Option Plans and Warrants to Purchase Common Stock [Abstract] Shares available for grant at end of year Stock Option Plans And Warrants To Purchase Commonstock [Text Block] Stock Option Plans and Warrants to Purchase Common Stock Stock option plans and warrants to Purchase common Stock. Concentrations [Abstract] Concentration Risk Disclosure [Text Block] Concentrations Commitments and Contingencies [Abstract] Commitments and Contingencies [Abstract] Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Operating Segments [Abstract] Business Segments [Abstract] Segment Reporting Disclosure [Text Block] Operating Segments Subsequent Events [Abstract] Subsequent Events [Text Block] Subsequent Events Consolidation, Policy [Policy Text Block] Principles of Consolidation Reclassification, Policy [Policy Text Block] Reclassification of Prior Year Presentation Segment Reporting, Policy [Policy Text Block] Operating Segments Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Grants Receivable [Policy Text Block] Contracts and grants receivable Grants Receivable Disclosure of accounting policy for grants receivable. Goodwill and Intangible Assets, Intangible Assets, Policy [Policy Text Block] Intangible Assets Impairment Or Disposal Of Long-Lived Assets, Policy [Policy Text Block] Impairment of Long-Lived Assets Fair Value Of Financial Instruments, Policy [Policy Text Block] Fair Value of Financial Instruments Revenue Recognition, Policy [Policy Text Block] Revenue Recognition Research and Development Expense, Policy [Policy Text Block] Research and Development Costs Accounting Warrants [Policy Text Block] Accounting for Warrants Disclosure of accounting policy for warrants. Share-Based Compensation, Option and Incentive Plans Policy [Policy Text Block] Share-based compensation Stock-Based Compensation Income Tax, Policy [Policy Text Block] Income Taxes Earnings Per Share, Policy [Policy Text Block] Earnings Per Share Use Of Estimates, Policy [Policy Text Block] Use of Estimates and Assumptions New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Schedule Of Earnings Per Share, Basic and Diluted [Table Text Block] Summary of earnings per share Schedule of Weighted Average Number of Shares [Table Text Block] Schedule of weighted average number of common shares Schedule of Finite-Lived Intangible Assets [Table Text Block] Summary of intangible assets Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Summary of annual amortization expense Schedule Of Assumptions Used In Valuation Of Warrants Issued [Table Text Block] Summary of assumptions used in connection with the valuation of warrants issued Schedule of assumptions used in valuation of warrants issued. Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Summary of fair value measurements using significant unobservable inputs (Level 3) Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Schedule of income tax benefit Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Schedule of deferred tax asset Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Schedule of reconciliation of income tax rate Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule Of Share-Based Compensation Arrangements By Share-Based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Award Type [Axis] Award Type [Axis] Award Type [Domain] Share-based Compensation Arrangements by Share-based Payment Award, Award Type and Plan Name [Domain] Equity Incentive Plan [Member] Equity Incentive Plan [Member] Equity incentive plan Share Based Compensation [Member] Share - based Compensation [Member] Share Based Compensation [Member] Stock Options [Member] Stock options [Member] Warrant [Member] Warrant [Member] Warrant [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of option and warrant activity Summary of option and warrant activity Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] Weighted-average range of exercise prices for options and warrants outstanding and exercisable Weighted-average range of exercise prices for options and warrants outstanding and exercisable Contractual Obligation, Fiscal Year Maturity Schedule [Table Text Block] Summary of future contractual obligations Schedule Of Segment Reporting Information, By Segment [Table Text Block] Summary of segmental information Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Report Date [Axis] Financial Statement Filing Date [Domain] November Two Thousand Sixteen [Member] November 2016 [Member] November two thousand sixteen. March Two Thousand Nineteen [Member] March 2019 [Member] March two thousand nineteen. Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Events [Member] Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] Nature Of Business (Textual) [Abstract] Nature of Business (Textual) Number of Operating Segments Number of operating segments Percentage Change In Cash and Cash Equivalents Percentage decrease in cash and cash equivalents Percentage change in cash and cash equivalents. Working Capital, Carrying Value Working capital, carrying value Working capital, carrying value. Derivative Liability Non-cash warrant liability Change In Working Capital Decrease in working capital Change in working capital. Percentage Of Change In Working Capital Percentage of decrease in working capital Percentage change in working capital. Research and Development Arrangement With Federal Government, Customer Funding To Offset Costs Incurred Active grant funding available Proceeds From Net Operating Losses Proceeds from net operating loss (NOL) sales Proceeds from net operating losses Proceeds from net operating losses. Long-term Debt, Gross Equity facility, available amount Debt Instrument, Maturity Date Equity facility, maturity date Maturity date Stockholders' Equity, Reverse Stock Split Reverse stock split, description Basic And Diluted Numerator [Abstract] Numerator: Basic and diluted numerator: Basic and diluted numerator Net Income (Loss) Available to Common Stockholders, Basic Net income/(loss) for basic earnings per share Gain (Loss) on Derivative Instruments, Net, Pretax Less change in fair value of warrant liability Less change in fair value of warrant liability Net Income (Loss) Available to Common Stockholders, Diluted Net loss for diluted earnings per share Net loss for diluted earnings per share Basic And Diluted Denominator [Abstract] Basic and diluted Denominator: Denominator: Basic and diluted denominator Assumed Conversion Of Dilutive Securities [Abstract] Assumed conversion of dilutive securities: Assumed conversion of dilutive securities. Conversion Of Dilutive Securities Common Stock Purchase Warrants Common stock purchase warrants Common stock purchase warrants. Weighted Average Number Diluted Shares Outstanding Adjustment Denominator for diluted earnings per share - adjusted weighted-average shares Option Indexed to Issuer's Equity [Table] Option Indexed to Issuer's Equity, Type [Axis] Option Indexed to Issuer's Equity, Type [Domain] Common Stock Purchase Warrants [Member] Common stock purchase warrants [Member] Common stock purchase warrants Option Indexed to Issuer's Equity [Line Items] Earnings Per Share, Diluted, Other Disclosures [Abstract] Dilutive adjustments to the weighted average number of common shares Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Antidilutive securities excluded from computation of earnings per shares Total Stock Option [Member] Option [Member] Range [Axis] Range [Axis] Range [Domain] Range [Domain] Minimum [Member] Minimum [Member] Maximum [Member] Maximum [Member] Scenario [Axis] Scenario, Unspecified [Domain] Directors Upon Re Election [Member] Directors Upon Re-election [Member] Permanent Employees Or Directors [Member] Permanent Employees or Directors [Member] Terminated Employees Or Directors [Member] Terminated Employees or Directors [Member] Summary Of Significant Accounting Policies (Textual) [Abstract] Summary of Significant Accounting Policies (Textual) Summary of Significant Accounting Policies. Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted average exercise price of outstanding derivative instruments Weighted average exercise price, outstanding Beginning Balance, weighted average options/warrants exercise price Ending Balance, weighted average options/warrants exercise price Finite-Lived Intangible Asset, Useful Life Intangible assets, estimated useful life Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Dividend yield Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Expected Term Expected life of stock option Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Volatility rate Share Based Compensation Arrangement By Share Based Payment Award, Fair Value Assumptions, Forfeiture Rate Forfeiture rate Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Forfeiture rate. Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk free interest rate Vesting Period Of Option Issued Upon Re Election Quarterly vesting period of stock options issued to directors upon re-election Vesting period of stock options issued to directors upon re-election. Period Of Stock Option Granted To Director and Employees Period of stock option granted to director and employees Period of stock option granted to director and employees. Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Options Vested Immediately Percentage of options, vested immediately Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested immediately. Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Options Vested Later Percentage of options, vested later till three year Expiration Of Options Upon Termination Of Employee Period of expiration of option upon termination of employee or director Expiration of options upon termination of employee. Period Of Re Measurement Of Option Price Period of re-measurement of option's price using the Black-Scholes model Period of re-measurement of option price. Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Options granted Issuance of stock option Granted Fair value of options price Fair value of options price Stock price Share price Shares Issuable Upon Exercise Of Outstanding Derivative Instruments Shares issuable upon exercise of outstanding derivative instruments Shares issuable upon exercise of outstanding derivative instruments such as option or warrants. Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights Stock option vesting, Description Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted, weighted average options/warrants exercise price Weighted average exercise price, granted Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Stock option, Expiration period Schedule Of Finite-Lived Intangible Assets [Table] Schedule of Finite-Lived Intangible Assets [Table] Finite-Lived Intangible Assets By Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Licensing Agreements [Member] Licenses [Member] Patents [Member] Patents [Member] Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets, Net [Abstract] Summary of intangible assets Weighted Average Amortization Period Years Weighted Average Remaining Amortization Period (Years) Finite lived intangible asset weighted average amortization period. Finite-Lived Intangible Assets, Gross, Total Cost Finite-Lived Intangible Assets, Accumulated Amortization Accumulated Amortization Finite-Lived Intangible Assets, Net, Total Net Book Value Net Book Value Finite-Lived Intangible Assets, Future Amortization Expense [Abstract] Annual amortization expense Finite-Lived Intangible Assets, Amortization Expense, Next Twelve Months 2016 Finite-Lived Intangible Assets, Amortization Expense, Year Two 2017 Finite-Lived Intangible Assets, Amortization Expense, Year Three 2018 Finite-Lived Intangible Assets, Amortization Expense, Year Four 2019 Intangible Assets (Textual) [Abstract] Intangible Assets (Textual) Amortization Of Intangible Assets Amortization expense Schedule of Short-term Debt [Table] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Equity Unit Purchase Agreements [Member] Equity Line Purchase Agreements [Member] Equity Line Facilities [Member] Short-term Debt [Line Items] Notes Payable Textual [Abstract] Notes Payable (Textual) Debt Instrument, Face Amount Promissory notes, principal amount Notes Payable Issuance of promissory notes, present value Debt Instrument, Interest Rate, Stated Percentage Interest rate Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Table] Exercised Warrants [Member] Exercised During 2015 [Member] Exercised warrants Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items] Fair Value Assumptions and Methodology for Assets and Liabilities [Abstract] Summary of assumptions used in connection with the valuation of warrants issued Number Of Shares Underlying Warrants Number of shares underlying the warrants Number of shares underlying the warrants. Fair Value Assumptions, Exercise Price Exercise price Exercise price Fair Value Assumptions, Weighted Average Volatility Rate Volatility Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Fair Value Assumptions, Expected Term Expected warrant life (years) Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] Summary of fair value measurements using significant unobservable inputs (Level 3) Fair Value, Measurement with Unobservable Inputs Reconciliations, Recurring Basis, Liability Value Balances for liability Warrant liability, Beginning balance Warrant liability, Ending balance Decrease In Warrants Exercised Decrease from Warrants Exercised in 2016 Increase decrease in warrants exercised. Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease) Amount of initial warrant liability Increase decrease in Fair Value Non-cash charge or the change in the fair value Sale of Stock [Axis] Sale of Stock [Domain] IPO [Member] June 2013 Registered public offering [Member] Warrant Liabilities1 [Abstract] Warrant Liabilities (Textual) Amount Of Initial Warrant Liability Amount of initial warrant liability Amount of initial warrant liability. Warrants Exercised Warrants Exercised Warrants exercised. Sale of Stock, Price Per Share Closing price of common stock as reported on OTC Markets Income tax benefit Foreign Income Tax Expense (Benefit), Continuing Operations Federal State and Local Income Tax Expense (Benefit), Continuing Operations State Components of Deferred Tax Assets [Abstract] Summary of deferred tax assets Deferred Tax Assets, Operating Loss Carryforwards Net operating loss carry forwards Deferred Tax Assets, Tax Credit Carryforwards Orphan drug and research and development credit carry forwards Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost Equity based compensation Deferred Tax Assets, Goodwill and Intangible Assets Intangibles Deferred Tax Assets, Gross Total Total Deferred Tax Assets, Valuation Allowance Valuation allowance Valuation allowance Deferred Tax Assets, Net of Valuation Allowance Net deferred tax assets Net deferred tax assets Effective Income Tax Rate Reconciliation, Percent [Abstract] Reconciliations of difference between income tax benefit computed at federal and state statutory tax rates and provision for income tax benefit Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Income tax loss at federal statutory rate Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent State tax benefits, plus sale of NJ NOLs, net of federal benefit Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate And Statetaxes Subtotal Subtotal Effective income tax rate reconciliation at federal statutory income tax rate and state taxes. Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Valuation allowance Effective Income Tax Rate Reconciliation, Percent Income tax benefit Operating Loss Carryforwards [Table] Income Tax Authority, Name [Axis] Income Tax Authority, Name [Domain] New Jersey Division of Taxation [Member] New Jersey [Member] Income Tax Authority [Axis] Income Tax Authority [Domain] Domestic Tax Authority [Member] Federal Tax [Member] Operating Loss Carryforwards [Line Items] Income Taxes Textual [Abstract] IncomeTaxes (Textual) Operating Loss Carryforwards Net operating losses Tax Credit Carryforward, Amount Tax credit Tax Credit Carryforward Expiration Date Description Description of tax credits, Expiration date Description of expiration date of the tax credit carryforward. Operating Loss Carryforwards, Expiration Date Net operating loss carry forwards, Expiration date Operating Loss Carryforwards, Limitations on Use Net operating loss carry forwards, Limitations on use Schedule of Equity Method Investments [Table] Related Party [Axis] Related Party [Domain] Kodiak [Member] Kodiak Capital [Member] Kingsbrook [Member] Kingsbrook [Member] River North [Member] River North [Member] Lincoln Park Capital Fund Llc [Member] Lincoln Park Capital Fund, LLC [Member] Lincoln Park Capital Fund, LLC (''Lincoln Park'') [Member] Scenario, Forecast [Member] December 31, 2016 [Member] Agreement [Axis] Agreement [Domain] Two Thousand And Thirteen Purchase Agreement [Member] 2013 Purchase Agreement [Member] Schedule of Equity Method Investments [Line Items] Schedule of Equity Method Investments [Line Items] Shareholders Equity (Textual) [Abstract] Shareholders' Equity (Textual) Equity Line Purchase Agreement Common Stock Right To Sell Purchase agreement common stock Common stock right to sell in future period Equity Line Purchase Agreement declared the right of equity investment sales. Weighted Average Price Of Common Stock Percentage Weighted average price of common stock percentage percentage of weighted average price of the common stock. Equity Line Purchase Agreement Maximum Amount Of Investment Maximum investment amount on shares Equity Line Purchase Agreement, maximum amount of investment. Equity Line Purchase Agreement Investment Minimum Ownership Percentage Investment ownership percentage Equity Line Purchase Agreement investment minimum ownership percentage. Debt Instrument, Redemption Price, Percentage of Principal Amount Redeemed Promissory note principal amount, percentage Cost Associated With Equity Line Purchase Agreement Issuance cost Cost associated with Equity Line Purchase Agreement Cost associated with Equity Line Purchase Agreement. Line of Credit Facility, Commitment Fee Percentage Commitment fee Stock Issued During Period Share Of Vested Stock Options Exercised Issuance of common stock upon exercise of vested stock options Stock issued during period share of vested stock options exercised. Closing Price Of Common Shares Closing price of common shares Closing price of common shares. Common Stock Purchase Agreement Description Common stock purchase agreement, Description Description of common stock purchase agreement. Maximum Commitment Shares Under Agreement Consist Of Commitment Fee Number of shares issued as commitment Maximum commitment shares under agreement consist of commitment fee. Stock Granted, Value, Share-based Compensation, Gross Value of shares granted Maximum Additional Commitment Shares Upon Relative Proportion Of Purchases Compared Maximum Additional Commitment Shares Upon Relative Proportion Of Purchases Compared Maximum additional commitment shares upon the relative proportion of purchases compared. Proceed From Common Stock Agreement Gross Proceed from common stock agreement gross Proceed from common stock agreement gross. Description Of Purchase Agreement Description of purchase agreement Description of purchase agreement. Sale of Stock, Number of Shares Issued in Transaction Number of common stock shares sold Issuance Of Commitment Shares Number of commitment shares issued Issuance of commitment shares. Sale of Stock, Consideration Received on Transaction Net proceeds from common stock sold Equity Line Purchase Agreements Description Equity line purchase agreements, Description Description of equity line purchase agreements. Debt Instrument, Fee Percentage of debt instrument fee, Description Plan Name [Axis] Plan Name [Domain] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Summary of equity incentive plan Summary of options/warrants activity Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Shares available for grant at plan approval Shares available for grant at end of year Number of options available under Equity Incentive Plan Shares available for grant at plan approval Shares available for grant at end of year Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Options outstanding, shares Beginning Balance Ending Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Forfeited Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised, weighted average options/warrants exercise price Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Forfeited, weighted average options exercise price Forfeited, weighted average options exercise price Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table] Exercise Price Range [Axis] Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Domain] Range One [Member] $3.0-$22.00 [Member] Range one. Range Two [Member] $22.60-$41.00 [Member] Range two. Range Three [Member] $46.40-$94.00 [Member] Range three. Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items] Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Beginning of Period [Abstract] Weighted-average Range of Exercise Prices for options/warrants outstanding and exercisable Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Lower Range Limit Exercise price range, lower range limit Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Upper Range Limit Exercise price range, upper range limit Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Outstanding Options, Weighted Average Remaining Contractual Term Weighted-Average Remaining Contractual Life in Years Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Number of Outstanding Options Outstanding Options/Warrants Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Number of Exercisable Options Exercisable Options/Warrants Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Income Statement Location [Axis] Income Statement Location [Domain] Research and Development Expense [Member] Research and Development [Member] General and Administrative Expense [Member] General and Administrative [Member] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Expired/Cancelled Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Expired, weighted average warrant exercise price Range Five [Member] $5.10-$5.30 [Member] Range five. Range Four [Member] $14.80-$20.50 [Member] Range four. Two Thousand Fifteen Equity Incentive Plan [Member] 2015 Equity Incentive Plan [Member] Two thousand fifteen equity incentive plan. Title of Individual [Axis] Relationship to Entity [Domain] Employees [Member] Employees [Member] Employees. Board of Directors Chairman [Member] Board [Member] Stock Option Plans And Warrants To Purchase Common Stock Textual [Abstract] Stock Option Plans and Warrants to Purchase Common Stock (Textual) Stock option plans and warrants to purchase common stock. Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted average exercise price, options Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Exercisable, weighted average remaining contractual term Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Options intrinsic value, exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Options intrinsic value Class of Warrant or Right, Exercise Price of Warrants or Rights Weighted average exercise price Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Compensation cost for stock options not yet recognized Concentrations Textual [Abstract] Concentrations (Textual) Deposits Deposits under Securities Investor Protection Corporation Schedule Of Operating Leased Assets [Table] Schedule of Operating Leased Assets [Table] Property, Plant and Equipment By Type [Axis] Property, Plant and Equipment by Type [Axis] Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Research and Development Arrangement [Member] Research and Development [Member] Property, Plant and Equipment, Other Types [Member] Property and Other Leases [Member] Operating Leased Assets [Line Items] Operating Leased Assets [Line Items] Operating Leases, Future Minimum Payments Due [Abstract] Summary of future contractual obligations Operating Leases, Future Minimum Payments Due, Next Twelve Months October 1 through December 31, 2016 Operating Leases, Future Minimum Payments, Due In Two Years 2017 2015 Operating Leases, Future Minimum Payments, Due In Three Years 2018 2016 Operating Leases, Future Minimum Payments, Due In Four Years 2019 2017 Operating Leases, Future Minimum Payments, Due in Five Years 2020 2018 Operating Leases, Future Minimum Payments Due Total Total Lease Arrangement, Type [Axis] Parties to Contractual Arrangement [Axis] Lease Arrangement, Type [Domain] Parties to Contractual Arrangement [Domain] Doctor Schaber [Member] Dr. Schaber [Member] Dr. Schaber. Commitments and Contingencies Textual [Abstract] Commitments and Contingencies (Textual) Commitments and contingencies. Number Of Common Shares Transferred To Third Party Number of common shares transferred to third party Number of common shares transferred to third party. Commitments, Fair Value Disclosure Commitments related to agreements Payment For Commitment Milestones Payment for commitment milestones Payment for commitment milestones. Percentage For Royalties Percentage for royalties Percentage for royalties. Monthly Rent Amount Before Increment Monthly rent amount before increment Monthly rent amount before increment. Monthly Rent Amount Before Increment, Per Square Foot Monthly rent amount before increment, per square foot Monthly rent per square foot, amount before increment. Monthly Rent Increase Rent increases Monthly rent increases. Monthly Rent Increases Per Square Feet Rent increase per square feet Monthly rent increases per square feet. Monthly Rent Amount After Increment Monthly rent amount after increment Monthly rent amount after increment. Monthly Rent Amount After Increment, Per Square Foot Monthly rent amount after increment, per square foot Monthly rent amount after increment, per square foot. Operating Leases, Rent Expense, Net Rent expense Number Of Months Afterthat Rent Increases Number of months after that rent increases Number of months after that rent increases. Number Of Remaining Months For Which Increased Rent Paid Number of remaining months for which increased rent paid Number of remaining months for which increased rent paid. Payments to Acquire Businesses, Net of Cash Acquired Assets acquired payments to cash Stock Issued During Period, Shares, Purchase of Assets Shares issued in connection with asset purchase agreement, Shares Lease Expiration Date Lease agreement expire Percentage Of Ownership Outstanding Stock Percentage of ownership outstanding stock Percentage of ownership outstanding stock. Shares Issued In Connection With Acquisition Of In Process Research And Development Shares issued in connection with acquisition of in-process research and development Shares issued in connection with acquisition of in process research and development. Schedule Of Segment Reporting Information, By Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Statement, Business Segments [Axis] Statement, Business Segments [Axis] Segment [Domain] Segment [Domain] Vaccines Bio Defense [Member] Vaccines/BioDefense [Member] Vaccines/BioDefense. Bio Therapeutics [Member] BioTherapeutics [Member] BioTherapeutics. Corporate [Member] Corporate [Member] Segment Reporting Information [Line Items] Segment Reporting Information [Line Items] Segment Reporting Information, Profit (Loss) [Abstract] Summary of segmental information Operating Segments Textual [Abstract] Operating Segments (Textual) Subsequent Event [Table] Subsequent Event [Line Items] Subsequent Events (Textual) Purchase Agreement Remaining Term Purchase agreement remaining term Purchase agreement remaining term. Equity Method Investment, Ownership Percentage Ownership percentage Warrants To Purchase Shares Exchange Cashless Exercise Basis Warrants to purchase shares exchange cashless exercise basis Warrants to purchase shares exchange cashless exercise basis. Increase Decrease In Warrant Liability Decrease in carrying value of warrant liability Increase (decrease) in warrant liability.