Entity Central Index Key
Long term debt current fair value.
Long term debt non current fair value.
Convertible debt noncurrent fair value.
Royalty linked notes current fair value.
Royalty linked notes noncurrent fair value.
Income tax reconciliation fair value adjustments on derivative financial instruments.
Cover [Abstract]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Year Focus
Document Fiscal Year Focus
Document Fiscal Period Focus
Document Fiscal Period Focus
Trading Symbol
Trading Symbol
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Current Reporting Status
Entity Current Reporting Status
Entity Voluntary Filers
Entity Voluntary Filers
Entity Filer Category
Entity Filer Category
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Ex Transition Period
Entity Ex Transition Period
ICFR Auditor Attestation Flag
Icfr Auditor Attestation Flag
Entity Shell Company
Entity Shell Company
Entity Interactive Data Current
Entity Interactive Data Current
Title of 12(b) Security
Security12b Title
Security Exchange Name
Security Exchange Name
Entity File Number
Entity File Number
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, Address Line Two
Entity Address Address Line2
Entity Address, Address Line Three
Entity Address Address Line3
Entity Address, City or Town
Entity Address City Or Town
Entity Address, Country
Entity Address Country
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Document Annual Report
Document Annual Report
Document Transition Report
Document Transition Report
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Public Float
Entity Public Float
Royalty-linked notes, current.
Royalty-linked notes noncurrent.
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Current portion of restricted cash
Restricted Cash Current
Total current assets
Assets Current
Property and equipment, net
Property Plant And Equipment Net
Restricted cash, less current portion
Restricted Cash And Cash Equivalents Noncurrent
Other assets
Other Assets Noncurrent
Total assets
Assets
Liabilities and Shareholders’ Deficit
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued expenses
Accrued Liabilities Current
Derivative liability
Derivative Liabilities Current
Current portion of long-term debt
Long Term Debt Current
Current portion of royalty-linked notes
Royalty Linked Notes Current
Other current liabilities
Other Liabilities Current
Income taxes payable
Taxes Payable Current
Total current liabilities
Liabilities Current
Long-term debt, less current portion
Long Term Debt Noncurrent
Royalty-linked notes, less current portion
Royalty Linked Notes Noncurrent
Other liabilities
Other Liabilities Noncurrent
Total liabilities
Liabilities
Commitments and contingencies (Note 13)
Commitments And Contingencies
Shareholders’ deficit:
Stockholders Equity [Abstract]
Undesignated preferred shares, $0.01 par value per share: 100,000,000 shares authorized at December 31, 2020 and December 31, 2019; no shares issued at December 31, 2020 and December 31, 2019
Preferred Stock Value
Ordinary shares, $0.01 par value per share: 150,000,000 shares authorized, 49,431,028 shares issued at December 31, 2020; 50,000,000 shares authorized, 14,868,973 shares issued at December 31, 2019
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated deficit
Retained Earnings Accumulated Deficit
Total shareholders' deficit
Stockholders Equity
Total liabilities and shareholders’ deficit
Liabilities And Stockholders Equity
Undesignated preferred shares, par value
Preferred Stock Par Or Stated Value Per Share
Undesignated preferred shares, authorized
Preferred Stock Shares Authorized
Undesignated preferred shares issued
Preferred Stock Shares Issued
Ordinary shares, par value
Common Stock Par Or Stated Value Per Share
Ordinary shares, shares authorized
Common Stock Shares Authorized
Ordinary shares, shares issued
Common Stock Shares Issued
Financing transaction costs.
Income Statement [Abstract]
Revenue
Revenue From Contract With Customer Excluding Assessed Tax
Operating expenses:
Operating Expenses [Abstract]
Research and development
Research And Development Expense
General and administrative
General And Administrative Expense
Total operating expenses
Operating Expenses
Operating loss
Operating Income Loss
Interest expense, net
Interest Income Expense Nonoperating Net
Financing transaction costs
Financing Transaction Costs
Adjustments to fair value of derivatives
Unrealized Gain Loss On Derivatives
Extinguishment of debt
Gains Losses On Extinguishment Of Debt
Other income, net
Other Nonoperating Income Expense
Total other expense
Nonoperating Income Expense
Loss before income taxes
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
Income tax expense
Income Tax Expense Benefit
Net loss and comprehensive loss
Net Income Loss
Net loss attributable to ordinary shareholders
Net Income Loss Available To Common Stockholders Basic
Net loss per share attributable to ordinary shareholders – basic and diluted
Earnings Per Share Basic And Diluted
Weighted average ordinary shares outstanding – basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Temporary equity stock issued during period shares new issues.
Redenomination of share capital.
Temporary equity redenomination of share capital.
Temporary equity shares conversion of convertible preferred stock.
Temporary equity value conversion of convertible preferred stock.
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Ordinary Shares
Common Stock [Member]
Additional Paid-In Capital
Additional Paid In Capital [Member]
Accumulated Deficit
Retained Earnings [Member]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
IPO
I P O [Member]
Class of Stock
Statement Class Of Stock [Axis]
Class of Stock
Class Of Stock [Domain]
Convertible Preferred Stock
Convertible Preferred Stock [Member]
Series B convertible preferred shares.
Series B Convertible Preferred Shares
Series B Convertible Preferred Shares [Member]
Statement [Line Items]
Statement [Line Items]
Beginning balance
Temporary Equity beginning balance (in shares)
Temporary Equity Shares Outstanding
Temporary Equity beginning balance
Temporary Equity Carrying Amount Attributable To Parent
Beginning balance (in shares)
Shares Outstanding
Issuance of Series B convertible preferred shares, net of issuance costs
Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock
Temporary equity,Issuance of convertible preferred shares,net of issuance costs (in shares)
Temporary Equity Stock Issued During Period Shares New Issues
Temporary equity,Issuance of convertible preferred shares,net of issuance costs
Temporary Equity Stock Issued During Period Value New Issues
Issuance of shares
Stock Issued During Period Value New Issues
Issuance of shares (in shares)
Stock Issued During Period Shares New Issues
Issuance of ordinary shares in conjunction with vesting of restricted share units
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
Issuance of ordinary shares in conjunction with vesting of restricted share units (in shares)
Stock Issued During Period Shares Restricted Stock Award Net Of Forfeitures
Exercise of share options
Stock Issued During Period Value Stock Options Exercised
Exercise of share options (in shares)
Stock Issued During Period Shares Stock Options Exercised
Issuance of ordinary shares under subscription agreement
Stock Issued During Period Value Issued For Services
Issuance of ordinary shares under subscription agreement (in shares)
Stock Issued During Period Shares Issued For Services
Redenomination of share capital
Redenomination Of Share Capital
Temporary equity,redenomination of share capital
Temporary Equity Redenomination Of Share Capital
Conversion of preferred shares to ordinary shares
Stock Issued During Period Value Conversion Of Convertible Securities
Temporary equity conversion of convertible preferred stock (in shares)
Temporary Equity Shares Conversion Of Convertible Preferred Stock
Temporary equity conversion of convertible preferred stock
Temporary Equity Value Conversion Of Convertible Preferred Stock
Conversion of preferred shares to ordinary shares (in shares)
Stock Issued During Period Shares Conversion Of Convertible Securities
Issuance of warrants for ordinary shares
Adjustments To Additional Paid In Capital Warrant Issued
Share-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Net loss
Ending balance
Temporary Equity ending balance (in shares)
Temporary Equity ending balance
Ending balance (in shares)
Non-cash gain (loss) on short term investments.
Interest on short-term investments.
Proceeds from private placement and rights offering, net of transactions costs.
Statement Of Cash Flows [Abstract]
Long-term Debt, Type
Longterm Debt Type [Axis]
Long-term Debt, Type
Longterm Debt Type [Domain]
Exchangeable senior subordinated notes due 2025.
Exchangeable Notes
Exchangeable Senior Subordinated Notes Due Two Thousand Twenty Five [Member]
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Net loss
Profit Loss
Adjustments to reconcile net loss to cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Depreciation
Depreciation
Share-based compensation expense
Share Based Compensation
Gain on short term investments
Gain Loss On Investments
Non-cash gain on short term investments
Noncash Gain Loss On Short Term Investments
Interest on short-term investments
Interest On Short Term Investments
Amortization of debt discount and deferred financing costs
Amortization Of Financing Costs And Discounts
Interest on exchangeable notes - non-cash
Interest Expense Debt
Financing transaction costs included in financing activities
Adjustments to fair value of derivatives
Extinguishment of debt
Other
Other Noncash Income Expense
Changes in operating assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Prepaid expenses and other current assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Other assets
Increase Decrease In Other Operating Assets
Accounts payable
Increase Decrease In Accounts Payable
Accrued expenses
Increase Decrease In Accrued Liabilities
Income taxes
Increase Decrease In Accrued Income Taxes Payable
Other liabilities
Increase Decrease In Other Operating Liabilities
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
Purchases of property and equipment
Payments To Acquire Property Plant And Equipment
Purchases of short-term investments
Payments To Acquire Investments
Proceeds from sale of short-term investments
Proceeds From Sale Of Short Term Investments
Net cash (used in) / provided by investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from PPP Loan
Proceeds From Issuance Of Long Term Debt
Repayments of long-term debt
Repayments Of Long Term Debt
Proceeds from private placement and rights offering, net of transactions costs
Proceeds From Private Placement And Rights Offering Net Of Transactions Costs
Proceeds from issuance of ordinary shares, net of transaction costs
Proceeds From Issuance Initial Public Offering
Proceeds from issuance of debt, net of debt issuance costs
Proceeds From Debt Net Of Issuance Costs
Proceeds from issuance of convertible preferred shares
Proceeds From Issuance Of Convertible Preferred Stock
Proceeds from exercise of share options
Proceeds From Stock Options Exercised
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
Effect of exchange rates on cash and cash equivalents
Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
Net increase / (decrease) in cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Cash, cash equivalents and restricted cash, at beginning of period
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
Cash, cash equivalents and restricted cash, at end of period
Supplemental Disclosure of Cash Flow Information:
Supplemental Cash Flow Information [Abstract]
Income tax paid—U.S.
Income Taxes Paid Net
Interest paid
Interest Paid Net
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Nature of Operations and Basis of Presentation
Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block]
Accounting Policies [Abstract]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Fair Value Disclosures [Abstract]
Fair Value of Financial Assets and Liabilities
Fair Value Disclosures [Text Block]
Prepaid expenses and other current assets.
Prepaid Expense And Other Assets Current [Abstract]
Prepaid Expenses and Other Current Assets
Prepaid Expenses And Other Current Assets [Text Block]
Property Plant And Equipment [Abstract]
Property and Equipment, Net
Property Plant And Equipment Disclosure [Text Block]
Leases [Abstract]
Leases
Lessee Operating Leases [Text Block]
Payables And Accruals [Abstract]
Accrued Expenses
Accounts Payable And Accrued Liabilities Disclosure [Text Block]
Debt Disclosure [Abstract]
Debt
Debt Disclosure [Text Block]
The entire disclosure for royalty-linked notes.
Royalty-Linked Notes
Royalty Linked Notes Disclosures [Text Block]
Equity [Abstract]
Shareholders' (Deficit) / Equity
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Share-Based Compensation
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Quarterly Financial Information Disclosure [Abstract]
Quarterly Financial Data (Unaudited)
Quarterly Financial Information [Text Block]
Condensed Consolidating Financial Statements
Condensed Financial Statements [Text Block]
Subsequent Events [Abstract]
Subsequent Events
Subsequent Events [Text Block]
Going concern.
Going concern
Going Concern Policy [Text Block]
Covid 19 global pandemic.
COVID-19 Global Pandemic
C O V I D19 Global Pandemic Policy [Text Block]
Use of Estimates
Use Of Estimates
Comprehensive Loss
Comprehensive Income Policy Policy [Text Block]
Consolidation
Consolidation Policy [Text Block]
Short-term investments
Marketable Securities Policy
Cash and Cash Equivalents
Cash And Cash Equivalents Policy [Text Block]
Foreign Currencies
Foreign Currency Transactions And Translations Policy [Text Block]
Property and Equipment
Property Plant And Equipment Policy [Text Block]
Leases
Lessee Leases Policy [Text Block]
Research and Development Expenses
Research And Development Expense Policy
Accrued research and development expenses policy.
Accrued Research And Development Expenses
Accrued Research And Development Expenses Policy [Text Block]
Patent costs policy.
Patent Costs
Patent Costs Policy [Text Block]
Share-Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Grant awards policy.
Grant Awards
Grant Awards Policy [Text Block]
Research and development credits policy.
Research and Development Credits
Research And Development Credits Policy [Text Block]
Fair Value of Financial Instruments
Fair Value Of Financial Instruments Policy
Borrowings
Debt Policy [Text Block]
Derivative Liability
Derivatives Policy [Text Block]
Royalty linked notes.
Royalty-Linked Notes
Royalty Linked Notes Policy [Text Block]
Ordinary Share Warrants.
Ordinary Share Warrants
Ordinary Share Warrant Policy [Text Block]
Concentration of Credit Risk
Concentration Risk Credit Risk
Income Taxes
Income Tax Policy [Text Block]
Net Loss Per Ordinary Share
Earnings Per Share Policy [Text Block]
Segment and Other Information
Segment Reporting Policy Policy [Text Block]
Retirement plan policy.
Retirement Plan
Retirement Plan Policy [Text Block]
Inventory
Inventory Policy [Text Block]
Contingent Consideration
Business Combinations Policy
Recently Adopted Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Property plant and equipment estimated useful life.
Schedule of Property and Equipment Depreciated Using the Straight-Line Method Over the Estimated Useful Life of Each Asset
Property Plant And Equipment Estimated Useful Life Table [Text Block]
Schedule of Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares Outstanding
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Operating expenses by geographic areas.
Schedule of Distribution of Total Operating Expenses by Geographical Area
Operating Expenses By Geographic Areas Table [Text Block]
Schedule of Distribution of Long-Lived Assets by Geographical Area
Long Lived Assets By Geographic Areas Table [Text Block]
Valuation Approach and Technique
Valuation Technique [Axis]
Valuation Approach and Technique
Valuation Technique [Domain]
Black-scholes and binomial lattice pricing models.
Black-Scholes and Binomial Lattice Pricing Models
Black Scholes And Binomial Lattice Pricing Models [Member]
Schedule of Financial Assets Measured at Fair Value
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques Table [Text Block]
Summary of Long-term Debt Carried at Amortized Cost on Consolidated Balance Sheet
Fair Value By Balance Sheet Grouping [Text Block]
Summary of Changes in Fair Value of Derivative Liability
Schedule Of Derivative Liabilities At Fair Value Table [Text Block]
Summary of Assumptions Used to Determine Fair Value of Options
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Summary of Prepaid Expenses and Other Current Assets
Deferred Costs Capitalized Prepaid And Other Assets Disclosure [Text Block]
Schedule of Property and Equipment and Related Accumulated Depreciation
Property Plant And Equipment [Text Block]
Schedule of right of use assets and lease liabilities.
Summary of Right-of-Use Assets and Lease Liabilities
Schedule Of Right Of Use Assets And Lease Liabilities Table [Text Block]
Schedule of Future Lease Payments Included in Measurement of Lease Liabilities on Condensed Consolidated Balance Sheet
Lessee Operating Lease Liability Maturity Table [Text Block]
Schedule of Accrued Expenses
Schedule Of Accrued Liabilities Table [Text Block]
2025 Exchangeable Notes
Summary of Balance of Exchangeable Notes
Schedule Of Debt Instruments [Text Block]
Schedule of Principal Payments on Outstanding Debt
Contractual Obligation Fiscal Year Maturity Schedule Table [Text Block]
Tabular disclosure of information pertaining to royalty linked notes.
Royalty linked notes.
Royalty Linked Notes [Abstract]
Summary of Royalty-Linked Notes
Schedule Of Royalty Linked Notes Table [Text Block]
Warrant
Warrant [Member]
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Performance RSU.
Performance RSUs
Performance R S U [Member]
Summary of Number of Options Outstanding and Weighted-average Exercise Price
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Summary of Number of RSUs Granted and Weighted-average Grant Date Fair Value of RSUs
Schedule Of Share Based Compensation Restricted Stock Units Award Activity Table [Text Block]
Summary of Share-based Compensation Expense
Schedule Of Compensation Cost For Share Based Payment Arrangements Allocation Of Share Based Compensation Costs By Plan Table [Text Block]
Schedule of Components of Income Tax Expense Benefits
Schedule Of Components Of Income Tax Expense Benefit Table [Text Block]
Summary of Components of Income (Loss) Before Provision for Income Taxes
Schedule Of Income Before Income Tax Domestic And Foreign Table [Text Block]
Summary of Effective Income Tax Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Summary of Significant Components of Deferred Tax Assets and Liabilities
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Summary of Gross Unrecognized Tax Benefits
Schedule Of Unrecognized Tax Benefits Roll Forward Table [Text Block]
Schedule of Unaudited Quarterly Financial Data
Schedule Of Quarterly Financial Information Table [Text Block]
Organization consolidation and presentation of financial statements.
Organization consolidation and presentation of financial statements.
Organization Consolidation And Presentation Of Financial Statements [Table]
Organization Consolidation And Presentation Of Financial Statements [Table]
Private placement and rights offering.
Private Placement and Rights Offering
Private Placement And Rights Offering [Member]
Royalty-linked subordinated notes.
RLNs
Royalty Linked Subordinated Notes [Member]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Minimum
Minimum [Member]
Maximum
Maximum [Member]
Private Placement
Private Placement [Member]
Rights Offering in connection with Private Placement.
Rights Offering in Connection with Private Placement
Rights Offering In Connection With Private Placement [Member]
Securities.
Securities
Securities [Member]
Consolidated Entities
Consolidated Entities [Axis]
Consolidated Entities
Consolidated Entities [Domain]
Iterum Therapeutics US Limited.
Iterum Therapeutics US Limited
Iterum Therapeutics U S Limited [Member]
Lender Name
Line Of Credit Facility [Axis]
Line of Credit Facility, Lender
Line Of Credit Facility Lender [Domain]
Silicon Valley Bank.
Silicon Valley Bank (SVB)
Silicon Valley Bank [Member]
Debt Instrument
Debt Instrument [Axis]
Debt Instrument, Name
Debt Instrument Name [Domain]
Paycheck Protection Program.
Paycheck Protection Program
Paycheck Protection Program [Member]
Direct offering.
Direct Offering
Direct Offering [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
June 3 securities purchase agreement.
June 3 SPA
June Three Securities Purchase Agreement [Member]
June 30 securities purchase agreement.
June 30 SPA
June Thirty Securities Purchase Agreement [Member]
October Offering [Member].
October Offering
October Offering [Member]
Pre-Funded Warrants [Member].
Pre-Funded Warrants
Pre Funded Warrants [Member]
October twenty two securities purchase agreement.
Purchase Agreement
October Twenty Two Securities Purchase Agreement [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Aggregate principal amount
Debt Instrument Face Amount
Debt instrument interest rate
Debt Instrument Interest Rate Stated Percentage
Share consolidation basis nominal value per share.
Share consolidation basis, Renominalisation value per share.
Reverse share split
Stockholders Equity Note Stock Split Conversion Ratio1
Share consolidation basis nominal value per share
Share Consolidation Basis Nominal Value Per Share
Share consolidation basis, Renominalisation value per share
Share Consolidation Basis Renominalisation Value Per Share
Number of shares issued
Offering price per share
Sale Of Stock Price Per Share
Net proceeds from issuance of stock after deducting underwriting discounts,commissions and offering cost
Aggregate initial offering price of securities authorized to issue.
Aggregate initial offering price of securities authorized to issue
Aggregate Initial Offering Price Of Securities Authorized To Issue
Unit price per debt instrument.
Number of debt instruments within each unit.
Debt instrument price per unit.
Debt instrument shares embedded within each unit shares.
Debt instrument shares embedded within each unit value.
Debt instrument percentage of net revenue from domestic sale for potential aggregate payments.
Debt instrument aggregate potential payment capped rate.
Debt instrument aggregate amount payable per unit.
Debt instrument shares embedded within each unit exchange price.
Maximum subscription units to be accepted
Common Stock Shares Subscribed But Unissued
Debt instrument price per unit
Unit Price Per Debt Instrument
Number of debt instruments within each notes
Number Of Debt Instruments Within Each Unit
Debt instrument price per unit
Debt Instrument Price Per Unit
Debt instrument, shares embedded within each unit, shares
Debt Instrument Shares Embedded Within Each Unit Shares
Debt instrument, shares embedded within each unit, value
Debt Instrument Shares Embedded Within Each Unit Value
Debt instrument, shares embedded within each unit, exchange price
Debt Instrument Shares Embedded Within Each Unit Exchange Price
Debt instrument, percentage of net revenue from domestic sale for potential aggregate payments
Debt Instrument Percentage Of Net Revenue From Domestic Sale For Potential Aggregate Payments
Aggregate amount payable per unit
Debt Instrument Aggregate Amount Payable Per Unit
Debt instrument, aggregate potential payment capped rate
Debt Instrument Aggregate Potential Payment Capped Rate
Proceeds from sale of securities
Proceeds From Sale Of Available For Sale Securities Debt
Description of deferring payment on US payroll taxes CARES Act.
Description of deferring payment on US payroll taxes
Description Of Deferring Payment On U S Payroll Taxes C A R E S Act
Debt instrument, remaining amount amortized.
Debt instrument maturity period
Debt Instrument Term
Debt instrument, description
Debt Instrument Description
Debt instrument, forgiveness loan
Debt Instrument Decrease Forgiveness
Debt instrument, remaining amount amortized
Debt Instrument Remaining Amount Amortized
Debt Instrument, equal monthly repayments
Debt Instrument Periodic Payment
Gross proceeds from issuance of common stock.
Class of warrant or right Warrants expiry date.
Class of warrant or right Warrants closing date.
Percentage of ordinary shares issued to purchase additional warrants.
Aggregate gross proceeds from ordinary shares
Gross Proceeds From Issuance Of Common Stock
Proceeds from registered direct offerings, net of transaction costs
Proceeds From Issuance Of Common Stock
Number of warrants to purchase ordinary shares
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
Warrants to purchase ordinary shares, exercise price
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
Warrants expiry date
Class Of Warrant Or Right Warrants Expiry Date
Warrants closing date
Class Of Warrant Or Right Warrants Closing Date
Percentage of ordinary shares issued to purchase warrants
Percentage Of Ordinary Shares Issued To Purchase Additional Warrants
Percentage of outstanding ordinary shares.
Percentage of ordinary share at election of purchaser.
Description of securities purchase agreement.
Percentage of outstanding ordinary shares
Percentage Of Outstanding Ordinary Shares
Percentage of ordinary share at election of purchaser
Percentage Of Ordinary Share At Election Of Purchaser
Description of purchase agreement
Description Of Securities Purchase Agreement
Net proceeds from underwritten public offering.
Underwritten public offering closing date.
Registered direct offering closing date.
Exercise of underwriters option in full to purchase additional shares closing date
Net losses
Accumulated deficit
Net proceeds from underwritten public offering
Net Proceeds From Underwritten Public Offering
Underwritten public offering closing date
Underwritten Public Offering Closing Date
Registered direct offering closing date
Registered Direct Offering Closing Date
Exercise of underwriters option in full to purchase additional shares closing date
Exercise Of Underwriters Option In Full To Purchase Additional Shares Closing Date
Cash Deposit Guarantee Scheme insured amount.
Accounting policies.
Accounting policies.
Accounting Policies [Table]
Accounting Policies [Table]
Cash and Cash Equivalents
Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Certificates Of Deposit
Certificates Of Deposit [Member]
Warrants issued.
Warrant Issued
Warrant Issued [Member]
Income Tax Authority, Name
Income Tax Authority Name [Axis]
Income Tax Authority, Name
Income Tax Authority Name [Domain]
U.S. Tax Authority
Internal Revenue Service I R S [Member]
Tax cuts and jobs act of 2017.
Tax Cuts and Jobs Act of 2017
Tax Cuts And Jobs Act Of2017 [Member]
Accounting Standards Update
Adjustments For New Accounting Pronouncements [Axis]
Accounting Standards Update
Type Of Adoption [Member]
ASU 2016-02
Accounting Standards Update201602 [Member]
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Cash, FDIC insured amount
Cash F D I C Insured Amount
Cash, DGS insured amount
Cash D G S Insured Amount
Restricted cash
Restricted Cash
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Leasehold Improvements
Leasehold Improvements [Member]
Furniture and Fixtures
Furniture And Fixtures [Member]
Laboratory equipment.
Laboratory Equipment
Laboratory Equipment [Member]
Computer Equipment
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Estimated useful lives
Property Plant And Equipment Estimated Useful Lives
Estimated useful life
Property Plant And Equipment Useful Life
Research and development grant awarded amount.
Cost reimbursement arrangement period of recognition.
Cost reimbursement arrangement recognition begin during period.
Research and development funding arrangement, sub award granted
Research And Development Grant Awarded Amount
Cost reimbursement arrangement recognition period
Cost Reimbursement Arrangement Period Of Recognition
Cost reimbursement arrangement recognition beginning period
Cost Reimbursement Arrangement Recognition Begin During Period
Type of Revenue [Extensible List]
Type Of Revenue Extensible List
Short-term investments
Short Term Investments
Recognized income tax positions measured at largest amount greater than percentage of being realized.
Recognized income tax positions measured at largest amount greater than percentage of being realized
Recognized Income Tax Positions Measured At Largest Amount Greater Than Percentage Of Being Realized
Federal statutory tax rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
Net operating loses carry back period.
Percentage elimination of taxable income limitations by allowing corporate entities to fully utilize NOL carryforwards to offset taxable income.
Percentage deduction of interest of adjusted taxable income plus business interest income by tax payers.
Net opertaing loss carry back period
Net Operating Loses Carry Back Period
Percentage elimination of taxable income limitations by allowing corporate entities to fully utilize NOL carryforwards to offset taxable income
Percentage Elimination Of Taxable Income Limitations By Allowing Corporate Entities To Fully Utilize N O L Carryforwards To Offset Taxable Income
Percentage deduction of interest of adjusted taxable income plus business interest income by tax payers
Percentage Deduction Of Interest Of Adjusted Taxable Income Plus Business Interest Income By Tax Payers
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Options to purchase ordinary shares.
Options to Purchase Ordinary Shares
Options To Purchase Ordinary Shares [Member]
Unvested restricted ordinary shares.
Unvested Restricted Ordinary Shares
Unvested Restricted Ordinary Shares [Member]
Unvested restricted stock units.
Unvested Restricted Share Units
Unvested Restricted Stock Units [Member]
Unvested performance restricted share units.
Unvested Performance Restricted Share Units
Unvested Performance Restricted Share Units [Member]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Potentially dilutive securities excluded from computation of diluted weighted-average shares outstanding
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Number of business segments
Number Of Operating Segments
Schedule Of Segment Reporting Information By Segment [Table]
Schedule Of Segment Reporting Information By Segment [Table]
Geographical
Statement Geographical [Axis]
Geographical
Segment Geographical [Domain]
Ireland
IRELAND
U.S.
UNITED STATES
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
Operating expenses
Long lived assets
Noncurrent Assets
Defined contribution plan employee minimum percentage on plan assets.
Defined contribution plan employee deferral percentage maximum.
Defined contribution plan, employee minimum percentage of total plan assets
Defined Contribution Plan Employee Minimum Percentage On Plan Assets
Defined contribution plan, maximum deferral rate
Defined Contribution Plan Employee Deferral Percentage Maximum
Defined Contribution Plan, Tax Status [Extensible List]
Defined Contribution Plan Tax Status Extensible List
Defined benefit plan, contribution by employer
Defined Benefit Plan Contributions By Employer
Inventory
Inventory Net
Milestone payment.
Milestone payments
Milestone Payment
Right-of-use asset
Operating Lease Right Of Use Asset
Lease liability
Operating Lease Liability
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Level 1
Fair Value Inputs Level1 [Member]
Level 2
Fair Value Inputs Level2 [Member]
Level 3
Fair Value Inputs Level3 [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Other assets – advance payment to supplier
Other Assets Fair Value Disclosure
Discounted cash flow discount rate.
Fair Value By Balance Sheet Grouping [Table]
Fair Value By Balance Sheet Grouping [Table]
Measurement Input Type
Measurement Input Type [Axis]
Measurement Input Type
Measurement Input Type [Domain]
Discount Rate
Measurement Input Discount Rate [Member]
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Fair Value Balance Sheet Grouping Financial Statement Captions [Line Items]
Discounted cash flow include a discount rates
Discounted Cash Flow Discount Rate
Measurement Basis
Fair Value By Measurement Basis [Axis]
Fair Value Disclosure Item Amounts [Default]
Portion At Fair Value Fair Value Disclosure [Member]
Fair Value Measurement
Fair Value Disclosure Item Amounts [Domain]
Book Value
Carrying Reported Amount Fair Value Disclosure [Member]
Approximate Fair Value
Estimate Of Fair Value Fair Value Disclosure [Member]
Current portion of long-term debt
Long Term Debt Current Fair Value
Long-term debt, less current portion
Long Term Debt Non Current Fair Value
Long-term exchangeable note
Convertible Debt Noncurrent Fair Value
Derivative liability - exchange option and change of control
Derivative Liabilities
Current portion of royalty-linked notes
Royalty Linked Notes Current Fair Value
Long-term royalty-linked notes, less current portion
Royalty Linked Notes Noncurrent Fair Value
Total
Long Term Debt Fair Value
Fair value of derivative liability related to rights offering.
Derivative liability exchange option fair value.
Derivative liability, change of control feature, fair value.
Debt instrument price per ordinary share
Fair value of derivative liability
Derivative Fair Value Of Derivative Liability
Fair value of derivative liability related to rights offering
Fair Value Of Derivative Liability Related To Rights Offering
Derivative liability for the exchange option, fair value
Derivative Liability Exchange Option Fair Value
Derivative liability, change of control feature, fair value
Derivative Liability Change Of Control Feature Fair Value
Debt instrument price per ordinary share
Debt Instrument Price Per Ordinary Share
Initial fair value upon issuance of the exchangeable notes in the private placement.
Fair value added upon issuance of exchangeable notes in the rights offering.
Balance at December 31, 2019
Initial fair value upon issuance of the Exchangeable Notes in the Private Placement
Initial Fair Value Upon Issuance Of Exchangeable Notes In Private Placement
Fair value added upon issuance of Exchangeable Notes in the Rights Offering
Fair Value Added Upon Issuance Of Exchangeable Notes In Rights Offering
Adjustment to fair value
Balance at December 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions And Methodology [Abstract]
Expected term in years
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Dividend rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Discount rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Discount For Postvesting Restrictions
Debt instrument aggregate amount of payments on royalty linked subordinated.
Debt instrument, discount rate applied for royalty linked notes.
RLNs liability
Debt instrument, aggregate potential payment capped value
Debt Instrument Aggregate Amount Of Payments On Royalty Linked Subordinated
Debt instrument, discount rate applied for royalty linked notes
Debt Instrument Discount Rate Applied For Royalty Linked Notes
Fair value, assets Level 1 to Level 2 transfers, amount
Fair Value Assets Level1 To Level2 Transfers Amount
Fair value, liabilities Level 1 to Level 2 transfers, amount
Fair Value Liabilities Level1 To Level2 Transfers Amount
Fair value, assets Level 2 to Level 1 transfers, amount
Fair Value Assets Level2 To Level1 Transfers Amount
Fair value, liabilities Level 2 to Level 1 transfers, amount
Fair Value Liabilities Level2 To Level1 Transfers Amount
Fair value, asset Level 3 transfers amount
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Net
Fair value, liabilities Level 3 transfers amount
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Transfers Net
Refundable FDA filing fee.
Short-term deposits current.
Research and development tax credit receivable current.
Prepaid research and development expenses current.
Refundable FDA filing fee
Refundable F D A Filing Fee
Short-term deposits
Short Term Deposits Current
Research and development tax credit receivable
Research And Development Tax Credit Receivable Current
Prepaid research and development expenses
Prepaid Research And Development Expenses Current
Prepaid insurance
Prepaid Insurance
Value added tax receivable
Value Added Tax Receivable Current
Other prepaid assets
Other Prepaid Expense Current
Deferred financing expenses
Deferred Costs Current
Total
Refundable FDA filing fee received.
Prepaid expense and other assets current.
Prepaid expense and other assets current.
Prepaid Expense And Other Assets Current [Table]
Prepaid Expense And Other Assets Current [Table]
Subsequent Event Type
Subsequent Event Type [Axis]
Subsequent Event Type
Subsequent Event Type [Domain]
Subsequent Event
Subsequent Event [Member]
Prepaid Expense And Other Assets Current [Line Items]
Prepaid Expense And Other Assets Current [Line Items]
Refundable FDA filing fee received
Refundable F D A Filing Fee Received
Laboratory Equipment
Equipment [Member]
Property and equipment, gross
Property Plant And Equipment Gross
Less: accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Property and equipment, net
Depreciation expense
Lessee operating lease terminate term.
Number of lease.
Lessee operating leases, expiration period.
Schedule Of Operating Leased Assets [Table]
Schedule Of Operating Leased Assets [Table]
Lease Contractual Term
Lease Contractual Term [Axis]
Lease Contractual Term
Lease Contractual Term [Domain]
Termination notice.
Termination Notice
Termination Notice [Member]
Office space and commercial property.
Office Space and Commercial Property
Office Space And Commercial Property [Member]
Commercial unit.
Commercial Unit
Commercial Unit [Member]
Operating Leased Assets [Line Items]
Operating Leased Assets [Line Items]
Right-of-use asset
Lease liability
Lessee, operating lease, description
Lessee Operating Lease Description
Lessee, operating lease, term of contract
Lessee Operating Lease Term Of Contract
Lessee, operating lease, option to terminate
Lessee Operating Lease Option To Terminate
Lessee, operating lease, terminate term
Lessee Operating Lease Terminate Term
Lessee, operating lease, option to extend
Lessee Operating Lease Option To Extend
Lessee, operating lease, renewal term
Lessee Operating Lease Renewal Term
Number of lease
Number Of Lease
Lessee operating leases, expiration period
Lessee Operating Leases Expiration Period
Lessee, operating sublease, option to extend
Lessee Operating Sublease Option To Extend
Operating lease cost for right - of - use assets
Operating Lease Cost
Sublease Income
Sublease Income
Cash paid for operating lease liabilities
Operating Lease Payments
Right-of-use assets obtained in exchange for new operating lease obligation
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
Weighted-average remaining lease term
Operating Lease Weighted Average Remaining Lease Term1
Weighted-average discount rate
Operating Lease Weighted Average Discount Rate Percent
Schedule of lease assets and liabilities.
Schedule Of Lease Assets And Liabilities [Abstract]
Other assets
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List]
Operating Lease Right Of Use Asset Statement Of Financial Position Extensible List
Other current liabilities
Operating Lease Liability Current
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]
Operating Lease Liability Current Statement Of Financial Position Extensible List
Other liabilities
Operating Lease Liability Noncurrent
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]
Operating Lease Liability Noncurrent Statement Of Financial Position Extensible List
Total lease liabilities
2021
Lessee Operating Lease Liability Payments Due Next Twelve Months
2022
Lessee Operating Lease Liability Payments Due Year Two
2023
Lessee Operating Lease Liability Payments Due Year Three
2024
Lessee Operating Lease Liability Payments Due Year Four
2025
Lessee Operating Lease Liability Payments Due Year Five
Thereafter
Lessee Operating Lease Liability Payments Due After Year Five
Total
Lessee Operating Lease Liability Payments Due
Less imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
Total lease liabilities
Accrued clinical trial costs current.
Accrued manufacturing expenses current.
Accrued payroll and bonus expenses
Employee Related Liabilities Current
Accrued other expenses
Other Accrued Liabilities Current
Accrued clinical trial costs
Accrued Clinical Trial Costs Current
Accrued manufacturing expenses
Accrued Manufacturing Expenses Current
Total
Loan and security agreement entered date.
Remaining borrowing facility available date.
Debt Instrument [Table]
Debt Instrument [Table]
Loan and Security Agreement.
Loan and Security Agreement
Loan And Security Agreement [Member]
Variable Rate
Variable Rate [Axis]
Variable Rate
Variable Rate [Domain]
Wall Street Journal prime rate.
Wall Street Journal Prime Rate
Wall Street Journal Prime Rate [Member]
Silicon Valley Bank and Life Sciences Fund II LLC.
Silicon Valley Bank and Life Sciences Fund II LLC
Silicon Valley Bank And Life Sciences Fund I I Limited Liability Company [Member]
Rights offering.
Rights Offering
Rights Offering [Member]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Loan and security agreement entered date
Loan And Security Agreement Entered Date
Funded amount under agreement
Line Of Credit
Maximum amount available under second draw
Line Of Credit Facility Remaining Borrowing Capacity
Remaining borrowing facility available date
Remaining Borrowing Facility Available Date
Maximum amount available under agreement
Line Of Credit Facility Maximum Borrowing Capacity
Non-utilization fee percentage of undrawn principal amount
Line Of Credit Facility Unused Capacity Commitment Fee Percentage
Debt instrument interest minimum fixed interest rate.
Final payment fee for loan, percentage.
Voluntary prepayment fee in first year.
Voluntary prepayment fee in second year.
Voluntary prepayment fee thereafter.
Final payment fee for loan.
Frequency of amortization payments
Line Of Credit Facility Frequency Of Payments
Date of first required payment of initial draw
Line Of Credit Facility Date Of First Required Payment1
Minimum fixed interest rate per annum
Debt Instrument Interest Minimum Fixed Interest Rate
Basis spread on interest rate
Debt Instrument Basis Spread On Variable Rate1
Final interest rate payment on outstanding principal
Final Payment Fee For Loan Percentage
Principal and interest payment, maturity date
Line Of Credit Facility Expiration Date1
Final payment fee
Final Payment Fee For Loan
Prepayment fee in first year
Voluntary Prepayment Fee In First Year
Prepayment fee in second year
Voluntary Prepayment Fee In Second Year
Prepayment fee thereafter
Voluntary Prepayment Fee Thereafter
Principal payment during the period
Line Of Credit Facility Periodic Payment Principal
Class of warrant or right percentage of purchase of additional ordinary shares equal to term loan divided by exercise price called by each warrant or right.
Percentage of purchase additional ordinary shares equal to term loan divided by applicable exercise price
Class Of Warrant Or Right Percentage Of Purchase Of Additional Ordinary Shares Equal To Term Loan Divided By Exercise Price Called By Each Warrant Or Right
Effective annual interest rate on outstanding debt
Debt Instrument Interest Rate Effective Percentage
Interest expense
Accretion of debt discounts and deferred financing costs
Debt instrument, payment terms
Debt Instrument Payment Terms
Capitalized financing transaction costs.
Financing transaction costs
Financing transaction costs, capitalized
Capitalized Financing Transaction Costs
January 2020 $1,000 exchangeable notes due January 31, 2025.
January 2020 $1,000 Exchangeable Notes due January 31, 2025
January Two Thousand Twenty One Thousand Exchangeable Notes Due January Thirty One Two Thousand Twenty Five [Member]
September 2020 $1,000 exchangeable notes due January 31, 2025.
September 2020 $1,000 Exchangeable Notes due January 31, 2025
September Two Thousand Twenty One Thousand Exchangeable Notes Due January Thirty One Two Thousand Twenty Five [Member]
Exchangeable Notes
Debt Instrument Carrying Amount
Unamortized discount and debt issuance costs
Debt Instrument Unamortized Discount Premium And Debt Issuance Costs Net
Exchangeable Notes, net
Long Term Debt
Debt instrument accrued interest.
Exchangeable Notes, Accrued Interest
Debt Instrument Accrued Interest
Debt instrument maturity date
Debt Instrument Maturity Date
2021
Long Term Debt Maturities Repayments Of Principal In Next Twelve Months
2022
Long Term Debt Maturities Repayments Of Principal In Year Two
2023
Long Term Debt Maturities Repayments Of Principal In Year Three
2024
Long Term Debt Maturities Repayments Of Principal In Year Four
2025
Long Term Debt Maturities Repayments Of Principal In Year Five
Thereafter
Long Term Debt Maturities Repayments Of Principal After Year Five
Total
Debt instrument outstanding portion.
Number of debt instruments issued.
Royalty-Linked Notes.
Royalty-Linked Notes
Royalty Linked Notes [Member]
Product and Service
Product Or Service [Axis]
Product and Service
Products And Services [Domain]
Sulopenem.
Sulopenem
Sulopenem [Member]
Number of debt instruments issued
Number Of Debt Instruments Issued
Debt instrument outstanding portion
Debt Instrument Outstanding Portion
Debt discounts
Debt Instrument Unamortized Discount
Estimated effective interest rate
Liability related to the sale of future royalties.
Amortization of discount and debt issuance costs related to sale of future royalties.
Total liability related to the sale of future royalties, on inception
Liability Related To Sale Of Future Royalties
Amortization of discount and debt issuance costs
Amortization Of Discount And Debt Issuance Costs Related To Sale Of Future Royalties
Total liability related to the sale of future royalties at December 31, 2020
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Counterparty Name
Counterparty Name [Axis]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
Supplier.
Supplier
Supplier [Member]
June 3 offering.
June 3 Offering
June3 Offering [Member]
June 30 offering.
June 30 Offering
June30 Offering [Member]
June 30 Securities Purchase Agreement.
June 30 SPA
June30 Securities Purchase Agreement [Member]
June 3 Securities Purchase Agreement.
Securities Purchase Agreement
June3 Securities Purchase Agreement [Member]
Preferred stock undesignated.
Undesignated Preferred Shares
Preferred Stock Undesignated [Member]
Series A convertible preferred shares.
Series A Convertible Preferred Shares
Series A Convertible Preferred Shares [Member]
Pfizer license agreement.
Pfizer License Agreement
Pfizer License Agreement [Member]
Title of Individual
Title Of Individual [Axis]
Title of Individual
Title Of Individual With Relationship To Entity [Domain]
Founders.
Founders
Founders [Member]
Series B-1 convertible preferred shares.
Series B-1 Convertible Preferred Shares
Series B1 Convertible Preferred Shares [Member]
Series B-1 convertible preferred shares.
Series B-2 Convertible Preferred Shares
Series B2 Convertible Preferred Shares [Member]
Class Of Stock [Line Items]
Class Of Stock [Line Items]
Increase in common stock shares authorized.
Increase in common stock, shares authorized
Increase In Common Stock Shares Authorized
Common stock maximum Shares authorized for subscription.
Common stock, maximum shares authorized for subscription
Common Stock Maximum Shares Authorized For Subscription
Issuance of ordinary shares under subscription agreement
Common Stock Shares Subscriptions
Payment receivable upon common stock subscription agreement
Receivable From Shareholders Or Affiliates For Issuance Of Capital Stock
Number of votes per common share.
Common stock rights and preferences.
Number of vote per common share
Number Of Vote Per Common Share
Common stock rights and preferences
Common Stock Rights And Preferences
Fair Value Inputs Quantitative Information [Abstract]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table]
Volatility
Measurement Input Price Volatility [Member]
Expected Term in Years
Measurement Input Expected Term [Member]
Dividend Rate
Measurement Input Expected Dividend Rate [Member]
Risk-free Interest Rate
Measurement Input Risk Free Interest Rate [Member]
Share Price
Measurement Input Share Price [Member]
Measurement input fair value of warrant issued.
Fair Value of Warrants Issued
Measurement Input Fair Value Of Warrant Issued [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Estimated fair value of warrant assumptions
Warrants And Rights Outstanding Measurement Input
Estimated fair value of warrant assumptions
Warrants And Rights Outstanding Term
Temporary equity shares issued price per share.
Temporary equity, shares authorized
Temporary Equity Shares Authorized
Temporary equity, par value
Temporary Equity Par Or Stated Value Per Share
Temporary equity, shares issued
Temporary Equity Shares Issued
Temporary equity shares price per share
Temporary Equity Shares Issued Price Per Share
Gross cash proceeds from Issuance of convertible preferred stock
Proceeds From Issuance Of Redeemable Convertible Preferred Stock
Conversion of debt amount
Debt Conversion Original Debt Amount1
Convertible preferred stock issued upon conversion
Convertible Preferred Stock Shares Issued Upon Conversion
Temporary equity additional shares issued.
Temporary equity, additional shares issued
Temporary Equity Additional Shares Issued
Preferred stock, conversion basis
Preferred Stock Conversion Basis
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Two thousand fifteen equity incentive plan.
2015 Plan
Two Thousand Fifteen Equity Incentive Plan [Member]
Two thousand eighteen equity incentive plan.
2018 Plan
Two Thousand Eighteen Equity Incentive Plan [Member]
Restricted Ordinary Shares
Restricted Stock [Member]
Vesting
Vesting [Axis]
Vesting
Vesting [Domain]
Tranche One
Share Based Compensation Award Tranche One [Member]
Two thousand fifteen equity incentive plan and two thousand eighteen equity incentive plan.
2015 Plan and 2018 Plan
Two Thousand Fifteen Equity Incentive Plan And Two Thousand Eighteen Equity Incentive Plan [Member]
Employee Stock Options
Employee Stock Option [Member]
Employees and directors stock options.
Employees and Directors
Employees And Directors Stock Options [Member]
Restricted Share Units (RSUs)
Restricted Stock Units R S U [Member]
Director
Director [Member]
Restricted ordinary shares and options and restricted share units and performance restricted share units.
Restricted Ordinary Shares, Options and Restricted Share Units and Performance Restricted Share Units
Restricted Ordinary Shares And Options And Restricted Share Units And Performance Restricted Share Units [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares authorized
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized
Number of ordinary shares available for issuance
Common Stock Capital Shares Reserved For Future Issuance
Increase in number of ordinary shares available to be granted, percentage
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Outstanding Stock Maximum
Share Based compensation arrangement by share based payment award percentage of remaining restricted shares vest on monthly basis.
Shares issued in the period
Share Based Compensation Arrangement By Share Based Payment Award Shares Issued In Period
Percentage of awards vested
Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage
Percentage of remaining restricted ordinary shares vest on monthly basis
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Remaining Restricted Shares Vest On Monthly Basis
Grant date fair value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
Expense recognized
Allocated Share Based Compensation Expense
Unamortized stock compensation expense
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other Than Options
Stock-based compensation expense, expected weighted average period for recognition
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Share option granted term
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Vesting period
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
Vesting rights
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Rights
Share based compensation arrangement by share based payment award fair value assumptions period of risk free interest rate based on estimated of U.S. treasury yield.
Risk-free interest rate based on estimate of U.S. treasury yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Period Of Risk Free Interest Rate Based On Estimated Of U S Treasury Yield
Share options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Unvested employee options outstanding
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
Unamortized compensation expense share options
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
Compensation Related Costs [Abstract]
Volatility, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
Volatility, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
Risk-free interest rate, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
Risk-free interest rate, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
Share price
Share Price
Fair value of option on grant date
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Exercise Price
Number of Shares, Options outstanding Beginning Balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Number of Shares, Granted
Number of Shares, Exercised
Number of Shares, Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Number of Shares, Expired
Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
Number of Shares, Options outstanding Ending Balance
Number of Shares, Exercisable at December 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Weighted Average Exercise Price, Options outstanding Beginning Balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Weighted Average Exercise Price, Granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Weighted Average Exercise Price, Exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Weighted Average Exercise Price, Forfeited
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Weighted Average Exercise Price, Expired
Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
Weighted Average Exercise Price, Options outstanding Ending Balance
Weighted Average Exercise Price, Exercisable at December 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Weighted Average Remaining Contractual Life in Years, Options outstanding
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Weighted Average Remaining Contractual Life in Years, Exercisable at December 31, 2019
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Aggregate Intrinsic Value, Options outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Aggregate Intrinsic Value, Options outstanding
Aggregate Intrinsic Value, Exercisable at December 31, 2020
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Weighted average grant date fair value, options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Number of shares, granted/awarded
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
Number of Shares, RSUs outstanding Beginning Balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
Number of Shares, Granted
Number of Shares, Shares vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
Number of Shares, Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
Number of Shares, RSUs outstanding Ending Balance
Weighted average grant date fair value per share, RSUs outstanding Beginning Balance
Weighted average grant date fair value per share, Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
Weighted average grant date fair value per share, Shares Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
Weighted average grant date fair value per share, Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
Weighted average grant date fair value per share, RSUs outstanding Ending Balance
Number of Shares, Shares vested
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Research and Development Expense
Research And Development Expense [Member]
General and Administrative Expense
General And Administrative Expense [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Share-based compensation expense
Unamortized compensation expense
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Income tax benefits.
Income tax.
Income tax.
Income Tax [Table]
Income Tax [Table]
Income Tax [Line Items]
Income Tax [Line Items]
Income tax benefits
Income Tax Benefit
Current
Current Income Tax Expense Benefit Continuing Operations [Abstract]
U.S.
Current Federal Tax Expense Benefit
Ireland
Current Foreign Tax Expense Benefit
Total Current
Current Income Tax Expense Benefit
Deferred
Deferred Income Tax Expense Benefit Continuing Operations [Abstract]
U.S.
Deferred Federal Income Tax Expense Benefit
Ireland
Deferred Foreign Income Tax Expense Benefit
Total Deferred
Deferred Income Tax Expense Benefit
Income Tax Provision
U.S.
Income Loss From Continuing Operations Before Income Taxes Domestic
Ireland
Income Loss From Continuing Operations Before Income Taxes Foreign
Total
Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
Effective income tax rate reconciliation fair value adjustments on derivative financial instruments.
Ireland
Revenue Commissioners Ireland [Member]
Statutory rate, Percentage
Impact of U.S. tax rate, Percentage
Effective Income Tax Rate Reconciliation Change In Enacted Tax Rate
Impact of valuation allowance, Percentage
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Research and development tax credit, Percentage
Effective Income Tax Rate Reconciliation Tax Credits Research
Adjustments for current tax of prior periods, Percentage
Effective Income Tax Rate Reconciliation Prior Year Income Taxes
Fair value movements on derivative financial instruments, Percentage
Effective Income Tax Rate Reconciliation Fair Value Adjustments On Derivative Financial Instruments
Other, net, Percentage
Effective Income Tax Rate Reconciliation Other Reconciling Items Percent
Effective tax rate, Percentage
Effective Income Tax Rate Continuing Operations
Statutory rate, Amount
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
Impact of U.S. tax rate, Amount
Income Tax Reconciliation Change In Enacted Tax Rate
Impact of valuation allowance, Amount
Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
Research and development tax credit, Amount
Income Tax Reconciliation Tax Credits Research
Adjustments for current tax of prior periods, Amount
Income Tax Reconciliation Prior Year Income Taxes
Fair value movements on derivative financial instruments, Amount
Income Tax Reconciliation Fair Value Adjustments On Derivative Financial Instruments
Other, net, Amount
Income Tax Reconciliation Other Reconciling Items
Deferred tax assets section 163 J interest expense limitations.
Deferred tax assets
Deferred Tax Assets Net [Abstract]
Share-based compensation
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
Depreciation
Deferred Tax Liabilities Property Plant And Equipment
Depreciation
Deferred Tax Assets Property Plant And Equipment
Net operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards
163(j) interest expense limitation
Deferred Tax Assets Section163 J Interest Expense Limitations
Other
Deferred Tax Assets Other
Valuation allowance
Deferred Tax Assets Valuation Allowance
Total deferred tax assets
Deferred Tax Assets Net
Deferred tax liabilities
Deferred Tax Liabilities Net [Abstract]
Deferred tax liabilities
Deferred Tax Liabilities
Total deferred tax assets
Net deferred tax asset
Deferred Tax Assets Liabilities Net
Net operating loss carryforwards
Operating Loss Carryforwards
Balance at January 1
Unrecognized Tax Benefits
Additions
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
Balance at December 31
Potential future regulatory and sales milestone payments upon achievement of net sales.
Other Commitments [Table]
Other Commitments [Table]
Other Commitments [Line Items]
Other Commitments [Line Items]
Potential future regulatory milestone and sales milestone payments upon achievement of net sales
Potential Future Regulatory And Sales Milestone Payments Upon Achievement Of Net Sales
Total operating expenses
Schedule Of Condensed Financial Statements [Table]
Schedule Of Condensed Financial Statements [Table]
Ownership
Ownership [Axis]
Ownership
Ownership [Domain]
Iterum Bermuda.
Iterum Therapeutics Bermuda Limited
Iterum Bermuda [Member]
Subsidiary guarantors.
Subsidiary Guarantors
Subsidiary Guarantors [Member]
Condensed Financial Statements Captions [Line Items]
Condensed Financial Statements Captions [Line Items]
Ownership percentage
Minority Interest Ownership Percentage By Parent
Subsequent Event [Table]
Subsequent Event [Table]
February underwritten offering.
February Underwritten Offering
February Underwritten Offering [Member]
Underwriting agreement.
Underwriting Agreement
Underwriting Agreement [Member]
Pursuant to the underwriting agreement.
Pursuant to the Underwriting Agreement
Pursuant To Underwriting Agreement [Member]
February securities purchase agreement.
February SPA
February Securities Purchase Agreement [Member]
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Offering closing date.
Option period to purchase additional ordinary shares.
Additional ordinary shares that can be purchased by underwriter.
Ordinary shares, issued and sold
Offering closing date
Offering Closing Date
Option period to purchase additional ordinary shares
Option Period To Purchase Additional Ordinary Shares
Additional ordinary shares that can be purchased by underwriter
Additional Ordinary Shares That Can Be Purchased By Underwriter
Net proceeds
Warrants expiry date
Warrants And Rights Outstanding Maturity Date