Components of Net Deferred Tax Assets (Detail) - USD ($) $ in Thousands |
Dec. 31, 2022 |
Dec. 31, 2021 |
|---|---|---|
| Deferred tax assets: | ||
| Net operating loss carryforwards | $ 542,537 | $ 542,800 |
| Research and development credits | 78,804 | 78,804 |
| Capitalized research costs | 4,369 | |
| Milestone Rights | 1,331 | 1,440 |
| Accrued expenses | 2,675 | 2,591 |
| Loss on purchase commitment | 23,117 | 24,845 |
| Non-qualified stock option expense | 7,686 | 5,684 |
| Capitalized patent costs | 8,058 | 7,518 |
| Other | 3,204 | 2,568 |
| Lease liability | 1,624 | 588 |
| Interest expense limitation | 10,991 | 5,696 |
| Depreciation | 22,157 | 22,983 |
| Deferred Product Revenue & Costs | 370 | 404 |
| Total net deferred tax assets | 706,923 | 695,921 |
| Valuation allowance | (705,034) | (695,094) |
| Net deferred tax assets | 1,889 | 827 |
| Deferred tax liabilities: | ||
| Right of use asset | (1,640) | (555) |
| Other prepaids | (249) | (272) |
| Total deferred tax liabilities | $ (1,889) | $ (827) |
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- Definition Deferred Tax Assets Capitalized Costs No definition available.
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- Definition Deferred Tax Assets Capitalized Research Expenses No definition available.
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- Definition Deferred tax assets interest expense limitation. No definition available.
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- Definition Deferred tax assets lease liabilities. No definition available.
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- Definition Deferred Tax Assets Loss on Purchase Commitment No definition available.
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- Definition Deferred Tax Assets Milestone Rights No definition available.
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- Definition Deferred tax assets product revenue and other. No definition available.
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- Definition Deferred Tax Assets, Tax Deferred Expense (Accrual Adjustment) No definition available.
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- Definition Deferred tax liabilities right of use asset. No definition available.
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- References No definition available.
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- References No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences, classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences from provisions, reserves, allowances, and accruals, classified as other. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of deferred tax consequences attributable to taxable temporary differences derived from prepaid expenses. No definition available.
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