Collaboration, Licensing and Other Arrangements - Revenue Allocation (Detail) - USD ($) $ in Millions |
1 Months Ended | 12 Months Ended | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oct. 31, 2021 |
Oct. 16, 2021 |
Apr. 30, 2022 |
Dec. 31, 2022 |
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| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | $ 50.9 | |||||||||||||||||||||||
| R&D Services and License | Over Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | [1] | $ 18.4 | ||||||||||||||||||||||
| Progress Measure | Ratably | |||||||||||||||||||||||
| Recognition Period | [2] | May 2021 - Oct 2021 | ||||||||||||||||||||||
| Pre-Commercial Services | Over Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | [1] | $ 4.6 | ||||||||||||||||||||||
| Progress Measure | Input | |||||||||||||||||||||||
| Recognition Period | [3] | % of completion of costs | ||||||||||||||||||||||
| Next-Gen R&D Services | Over Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | [1] | $ 7.2 | ||||||||||||||||||||||
| Progress Measure | Input | |||||||||||||||||||||||
| Recognition Period | [3] | % of completion of costs | ||||||||||||||||||||||
| Facility Expansion Services | Point In Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | [1],[4] | $ 20.7 | ||||||||||||||||||||||
| Recognition Period | [4],[5] | Transfer of control | ||||||||||||||||||||||
| Collaboration and License Agreement | United Therapeutics Corporation | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | $ 50.9 | |||||||||||||||||||||||
| Collaboration and License Agreement | R&D Services and License | United Therapeutics Corporation | Over Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Progress Measure | [6] | Ratably | Ratably | Ratably | ||||||||||||||||||||
| Recognition Period | [6],[7] | Aug 2021 - Oct 2021 | Aug 2021 - Oct 2021 | Aug 2021 - Oct 2021 | ||||||||||||||||||||
| Collaboration and License Agreement | Next-Gen R&D Services | United Therapeutics Corporation | Over Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | [1],[8] | $ 4.8 | $ 5.9 | $ 10.0 | ||||||||||||||||||||
| Progress Measure | [8] | Input | Input | Input | ||||||||||||||||||||
| Recognition Period | [8],[9] | % of completion of costs | % of completion of costs | % of completion of costs | ||||||||||||||||||||
| Clinical Supplies | Collaboration and License Agreement | United Therapeutics Corporation | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | $ 105.8 | |||||||||||||||||||||||
| Clinical Supplies | Collaboration and License Agreement | R&D Services and License | United Therapeutics Corporation | Over Time | ||||||||||||||||||||||||
| Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||||||||
| Total transaction price | $ 105.8 | |||||||||||||||||||||||
| Allocation of Price | 100.00% | |||||||||||||||||||||||
| Progress Measure | Ratably | |||||||||||||||||||||||
| Recognition Period | [10] | Sep 2018 - Dec 2021 | ||||||||||||||||||||||
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