Cover [Abstract] Entity Addresses [Table] Entity Addresses, Address Type [Axis] Address Type [Domain] Business Contact [Member] Document Information [Line Items] Contact Personnel Name Entity Primary SIC Number Entity Central Index Key Entity Central Index Key Entity Registrant Name Entity Registrant Name Document Type Document Type City Area Code City Area Code Entity Address, City or Town Entity Address, City or Town Entity Address, Address Line One Entity Address, Address Line One Entity Address, Address Line Two Entity Address, Address Line Two Entity Emerging Growth Company Entity Emerging Growth Company Entity Small Business Entity Small Business Entity Filer Category Entity Filer Category Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Address, State or Province Entity Address, State or Province Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Tax Identification Number Local Phone Number Local Phone Number Amendment Flag Amendment Flag Statement of Financial Position [Abstract] Liabilities and Equity Total liabilities and stockholders' equity Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity Preferred Stock, Value, Issued Preferred stock - $0.000001 par value - authorized, 5,000,000 as of June 30, 2023 and December 31, 2022; issued and outstanding, 0 as of June 30, 2023 and December 31, 2022 Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income (loss) Retained Earnings (Accumulated Deficit) Accumulated deficit Common Stock, Value, Issued Common stock - $0.000001 par value - authorized, 20,000,000 as of June 30, 2023 and December 31, 2022; issued and outstanding, 8,804,285 as of June 30, 2023 and 8,529,669 as of December 31, 2022 Stockholders' Equity Attributable to Parent Total stockholders' equity Balance, beginning Balance, ending Liabilities [Abstract] Liabilities Liabilities Total liabilities Liabilities, Current [Abstract] Current liabilities Accounts Payable and Accrued Liabilities, Current Accounts payable and other liabilities Liabilities, Current Total current liabilities Operating Lease, Liability, Current Operating lease liability Less: current portion Finance Lease, Liability, Current Finance lease liability Less: current portion Operating Lease, Liability, Noncurrent Non-current operating lease liability Non-current lease liabilities—December 31, 2022 Finance Lease, Liability, Noncurrent Non-current finance lease liability Non-current lease liabilities—December 31, 2022 Assets [Abstract] Assets Assets, Current [Abstract] Current assets Debt Securities, Available-for-Sale, Current Short-term investments Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Amortized Cost Other Assets, Current Other current assets Assets, Current Total current assets Property, Plant and Equipment, Net Property and equipment, net Operating Lease, Right-of-Use Asset Operating lease right-of-use asset Operating lease right-of-use assets Finite-Lived Intangible Assets, Net Intangible asset, net Net intangible asset Other Assets, Noncurrent Other non-current assets Assets Total assets Preferred Stock, Shares Authorized Preferred stock, shares authorized (in shares) Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollars per share) Preferred Stock, Shares Outstanding Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Issued Preferred stock, shares issued (in shares) Common Stock, Shares, Outstanding Common stock, shares outstanding (in shares) Common Stock, Shares, Issued Common stock, shares issued (in shares) Common Stock, Shares Authorized Common stock, shares authorized (in shares) Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Income Statement [Abstract] Operating Income (Loss) Loss from operations Other Comprehensive Income (Loss), Net of Tax [Abstract] Comprehensive income (loss) Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Unrealized gain (loss) on available-for-sale securities Unrealized gain (loss) on available-for-sale securities Net Income (Loss) Attributable to Parent Net loss Net loss Nonoperating Income (Expense) Other income (loss), net Interest Income (Expense), Net Interest income Weighted Average Number of Shares Outstanding, Basic Basic weighted average number of shares outstanding (in shares) Earnings Per Share, Diluted Net loss per share - diluted (in dollars per share) Earnings Per Share, Basic Net loss per share - basic (in dollars per share) Weighted Average Number of Shares Outstanding, Diluted Diluted weighted average common shares outstanding (in shares) Operating Income (Loss) [Abstract] Operating expenses Impairment, Long-Lived Asset, Held-for-Use Impairment of property and equipment Operating Expenses Total operating expenses General and Administrative Expense General and administrative Research and Development Expense Research and development Statement of Cash Flows [Abstract] Supplemental Cash Flow Information [Abstract] Supplemental disclosure of non-cash investing and financing activities: Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Finance lease liabilities arising from obtaining right-of-use asset Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Operating lease liabilities arising from obtaining right-of-use asset Capital Expenditures Incurred but Not yet Paid Purchases of property and equipment unpaid at period-end Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash, cash equivalents, and restricted cash, beginning of period Cash, cash equivalents, and restricted cash, end of period Total cash, cash equivalents, and restricted cash Net Cash Provided by (Used in) Operating Activities [Abstract] Operating activities Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Other Operating Assets Other current assets and other non-current assets Increase (Decrease) in Operating Lease Liability Operating lease liabilities Increase in lease liability Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts payable and accrued liabilities Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Share-Based Payment Arrangement, Noncash Expense Stock-based compensation Depreciation, Depletion and Amortization Depreciation and amortization Operating Lease, Right-of-Use Asset, Amortization Expense Amortization of operating lease right-of-use assets Accretion (Amortization) of Discounts and Premiums, Investments Amortization and accretion of premiums/discounts on available-for-sale securities Gain (Loss) on Disposition of Property Plant Equipment Gain (Loss) on sale/disposal of property and equipment Gain (Loss) on disposition of property plant equipment Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net change in cash, cash equivalents, and restricted cash during the period Net Cash Provided by (Used in) Financing Activities [Abstract] Financing activities Finance Lease, Principal Payments Payment on finance lease obligations Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised Proceeds from the issuance of common stock under Employee Stock Purchase Plan Proceeds from Stock Options Exercised Proceeds from exercise of stock options Net Cash Provided by (Used in) Financing Activities Net cash provided by (used in) financing activities Net Cash Provided by (Used in) Investing Activities [Abstract] Investing activities Proceeds from Sale of Property, Plant, and Equipment Proceeds from sale of property and equipment Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-Sale Proceeds from maturities of available-for-sale securities Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Acquire Debt Securities, Available-for-Sale Purchases of available-for-sale securities Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities Statement of Stockholders' Equity [Abstract] Statement [Table] Statement [Table] Revision of Prior Period [Axis] Revision of Prior Period [Domain] Previously Reported [Member] Statement [Line Items] Statement [Line Items] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Shares issued upon exercises of stock options (in shares) Options exercised (in shares) Options exercised (in shares) Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of shares under Employee Stock Purchase Plan Proceeds from ESPP APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation Stock Issued During Period, Value, Stock Options Exercised Shares issued upon exercises of stock options Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Shares issued upon vesting of restricted stock units (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of shares under Employee Stock Purchase Plan (in shares) Shares, Outstanding Balance, beginning (in shares) Balance, ending (in shares) Stock Issued During Period Shares Pre Funded Warrants Shares issued upon the exercise of pre-funded warrants (in shares) Stock issued during period shares pre funded warrants. Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Pre Funded Warrants [Member] Pre-Funded Warrants Prefunded Warrants Pre funded warrants. Equity Components [Axis] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock Common stock Additional Paid-in Capital [Member] Additional Paid-In Capital Retained Earnings [Member] Accumulated Deficit AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Income (Loss) Organization, Consolidation and Presentation of Financial Statements [Abstract] Nature of Operations [Text Block] Nature of operations Accounting Policies [Abstract] Significant Accounting Policies [Text Block] Summary of significant accounting policies Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract] Cash Cash Equivalents And Restricted Cash 1 Disclosure [Text Block] Cash, cash equivalents, and restricted cash Cash Cash Equivalents And Restricted Cash Disclosure Text Block. Investments, Debt and Equity Securities [Abstract] Investment [Text Block] Investments Property, Plant and Equipment [Abstract] Property, Plant and Equipment Disclosure [Text Block] Property and equipment, net Goodwill and Intangible Assets Disclosure [Abstract] Intangible Assets Disclosure [Text Block] Intangible asset, net Payables and Accruals [Abstract] Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accounts payable and other liabilities Leases [Abstract] Lessee, Operating Leases [Text Block] Leases Equity [Abstract] Stockholders' Equity Note Disclosure [Text Block] Equity Earnings Per Share [Abstract] Earnings Per Share [Text Block] Net loss per share Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income taxes License Agreement [Abstract] License Agreement Disclosure [Text Block] License and patent agreements License Agreement Disclosure. Retirement Benefits [Abstract] Defined Contribution Plan [Text Block] 401(k) plan Restructuring and Related Activities [Abstract] Restructuring and Related Activities Disclosure [Text Block] Restructuring Plan Subsequent Events [Abstract] Subsequent Events [Text Block] Subsequent Events Research and Development Expense, Policy [Policy Text Block] Research and development costs Share-Based Payment Arrangement [Policy Text Block] Accounting for stock-based compensation Segment Reporting, Policy [Policy Text Block] Segment reporting Basis of Accounting, Policy [Policy Text Block] Basis of presentation Earnings Per Share, Policy [Policy Text Block] Net loss per share Fair Value of Financial Instruments, Policy [Policy Text Block] Fair value of financial instruments Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of credit risk Costs Associated with Exit or Disposal Activity or Restructuring [Policy Text Block] Restructuring Charges New Accounting Pronouncements, Policy [Policy Text Block] Recently issued and recently adopted accounting standards Investment, Policy [Policy Text Block] Investments Intangible Assets, Finite-Lived, Policy [Policy Text Block] Intangible assets subject to amortization Income Tax, Policy [Policy Text Block] Income taxes Use of Estimates, Policy [Policy Text Block] Use of estimates and assumptions Lessee, Leases [Policy Text Block] Leases Cash and Cash Equivalents, Policy [Policy Text Block] Cash, cash equivalents, and restricted cash Property, Plant and Equipment, Policy [Policy Text Block] Property and equipment, net Schedule of Cash and Cash Equivalents [Table Text Block] Schedule of Cash and Cash Equivalents Restrictions on Cash and Cash Equivalents [Table Text Block] Restrictions on Cash and Cash Equivalents Restrictions on Cash and Cash Equivalents Fair Value, Assets Measured on Recurring Basis [Table Text Block] Schedule of Fair Value, Assets Debt Securities, Available-for-Sale [Table Text Block] Schedule of Investments Property, Plant and Equipment [Table Text Block] Schedule of Property and Equipment Schedule of Finite-Lived Intangible Assets [Table Text Block] Schedule of Intangible Asset Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Schedule of Accounts Payable and Other Liabilities Schedule of Cash Flow, Supplemental Disclosures [Table Text Block] Supplemental Cash flow Information Related to Leases Lessee, Operating Lease, Liability, Maturity [Table Text Block] Schedule of Company's Operating Lease Liability Finance Lease, Liability, Fiscal Year Maturity [Table Text Block] Schedule of Company's Finance Lease Liability Lease, Cost [Table Text Block] Schedule of Components of Lease Expense Schedule Of Supplemental Balance Sheet Information Related To Leases [Table Text Block] Supplemental Balance Sheet Information Related to Leases Tabular disclosure of supplemental balance sheet information related to leases for the periods presented. Schedule of Unvested Restricted Stock Units Roll Forward [Table Text Block] Schedule of Unvested Restricted Stock Units Roll Forward Share-Based Payment Arrangement, Option, Activity [Table Text Block] Schedule of Stock Option Activity Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Weighted Average Assumptions Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Schedule of RSU Activity Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Summary of Stock-based Compensation Expense Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Securities Excluded From Computation of Earnings Per Share Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Schedule of Income Tax Recovery Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] Schedule of Net (Loss) Income Before Taxes Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Components of Deferred Income Tax Assets Schedule of Restructuring Reserve by Type of Cost [Table Text Block] Summary of Restructuring Charges Significant Accounting Policies [Table] Significant Accounting Policies [Table] Significant Accounting Policies [Table] Long-Lived Tangible Asset [Axis] Property, Plant and Equipment, Type [Axis] Long-Lived Tangible Asset [Domain] Property, Plant and Equipment, Type [Domain] Office Building [Member] Office space Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Class of Stock [Axis] Class of Stock [Axis] Class of Stock [Domain] Class of Stock [Domain] Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Number of Operating Segments Number of operating segments Debt Securities, Available-for-Sale, Unrealized Loss Position Fair value, investments, unrealized loss Property, Plant and Equipment, Useful Life Property and equipment, useful life Class of Warrant or Right, Outstanding Outstanding pre-funded warrants (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividends Expected dividends Lessee, Operating Lease, Term of Contract Lease term Security Deposit Security deposit Cash deposit Debt Securities, Available-for-Sale, Allowance for Credit Loss Allowance for credit loss Statistical Measurement [Axis] Statistical Measurement [Axis] Statistical Measurement [Domain] Statistical Measurement [Domain] Minimum [Member] Minimum Maximum [Member] Maximum Restricted Cash and Cash Equivalents Restricted cash Schedule of Servicing Assets at Fair Value [Table] Schedule of Servicing Assets at Fair Value [Table] Measurement Frequency [Axis] Measurement Frequency [Axis] Measurement Frequency [Domain] Measurement Frequency [Domain] Fair Value, Recurring [Member] Fair Value, Recurring Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items] Cash and Cash Equivalents, Fair Value Disclosure Money market funds Fair Value Investments, Fair Value Disclosure U.S. treasury securities Assets, Fair Value Disclosure Total financial assets Financial Instrument [Axis] Financial Instrument [Axis] Financial Instruments [Domain] Financial Instruments [Domain] US Treasury Securities [Member] U.S. treasury securities Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV [Domain] Fair Value, Inputs, Level 1 [Member] Level 1 Fair Value, Inputs, Level 2 [Member] Level 2 Fair Value, Inputs, Level 3 [Member] Level 3 Money Market Funds [Member] Money market funds Debt Securities, Available-for-Sale [Table] Debt Securities, Available-for-Sale [Table] Debt Securities, Available-for-Sale [Line Items] Debt Securities, Available-for-Sale [Line Items] Cash and Cash Equivalents [Abstract] Cash equivalents: Debt Securities, Available-for-Sale [Abstract] Short-term investments: Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Gross Unrealized Losses Debt Securities, Available-for-Sale Fair Value Debt Securities, Available-for-Sale, Amortized Cost Amortized Cost Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Gross Unrealized Gains Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, Accumulated Depreciation and Amortization Accumulated Amortization Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, before Accumulated Depreciation and Amortization Cost Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, after Accumulated Depreciation and Amortization Net Book Value Furniture, Fixtures, And IT Equipment [Member] Furniture, fixtures, and IT equipment Furniture, Fixtures, And IT Equipment Laboratory Equipment [Member] Laboratory equipment Laboratory equipment. Depreciation Depreciation expense Finite-Lived Intangible Assets, Gross Cost Finite-Lived Intangible Asset, Useful Life Intangible asset useful life Amortization of Intangible Assets Amortization expense Finite-Lived Intangible Assets, Accumulated Amortization Accumulated amortization Accounts Payable, Trade, Current Trade accounts payable Accrued Clinical Expenses Current Accrued clinical and preclinical expenses Carrying value as of the balance sheet date of obligations incurred through that date and payable for clinical studies, which covers fees paid to CROs, investigative sites in connection with clinical studies and contract manufacturers in connection with the production of clinical study materials; and fees paid to vendors in connection with the preclinical development activities. Accounts Payable and Other Accrued Liabilities, Current Accounts payable and other liabilities Other Accrued Liabilities, Current Other accrued liabilities Employee-related Liabilities, Current Accrued compensation and vacation Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Name of Property [Axis] Name of Property [Axis] Name of Property [Domain] Name of Property [Domain] Office Space, Additional Offices and Laboratory [Member] Office space, additional offices and laboratory Office Space, Additional Offices and Laboratory Office Space, Principal Executive Offices and Laboratory [Member] Office space, principal executive offices and laboratory Office Space, Principal Executive Offices and Laboratory Geographical [Axis] Geographical [Axis] Geographical [Domain] Geographical [Domain] WASHINGTON Washington Number Of Option To Extend Lease Number of option to extend leases Number of option to extend lease. Tenant Improvement Allowance Tenant improvements (up to) Amount of tenant improvement allowance pursuant to lease arrangements. Finance Lease, Right-of-Use Asset, after Accumulated Amortization Finance lease right-of-use assets Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Increase (Decrease) In Operating Lease Right Of Use Assets Increase in right-of-use-asset Increase (Decrease) In Operating Lease Right Of Use Assets Lessee, Operating Lease, Renewal Term Lease agreement extended period Area of Real Estate Property Square feet of office space leased Operating Lease, Sublease, Base Lease Payments Sublease, base lease payments Operating Lease, Sublease, Base Lease Payments Credit Facility [Axis] Credit Facility [Axis] Credit Facility [Domain] Credit Facility [Domain] Standby Letters of Credit [Member] Standby Letters of Credit Lessee Disclosure [Abstract] Finance lease cost Finance Lease, Interest Expense Interest on lease liabilities Finance Lease, Right-of-Use Asset, Amortization Amortization of right-of-use asset Operating Lease, Cost Operating lease cost Short-Term Lease, Cost Short term lease cost Lease, Cost Total net lease cost Variable Lease, Cost Variable lease cost Finance Lease, Weighted Average Discount Rate, Percent Weighted average discount rate—finance leases Finance Lease, Weighted Average Remaining Lease Term Weighted average remaining lease term—finance leases Operating Lease, Weighted Average Remaining Lease Term Weighted average remaining lease term—operating leases Operating Lease, Weighted Average Discount Rate, Percent Weighted average discount rate—operating leases Finance Lease, Principal and Interest Payments Cash paid for amounts included in the measurement of finance lease liabilities Finance Lease, Principal and Interest Payments Operating Lease, Payments Cash paid for amounts included in the measurement of operating lease liabilities Finance Lease, Liability, to be Paid [Abstract] Finance Lease Finance Lease, Liability, to be Paid, Year One 2023 Finance Lease, Liability, to be Paid, Year Two 2024 Finance Lease, Liability, to be Paid, Year Three 2025 Finance Lease, Liability, to be Paid, Year Four 2026 Finance Lease, Liability, to be Paid, Year Five 2027 Finance Lease, Liability, to be Paid, after Year Five Thereafter Finance Lease, Liability, to be Paid Total undiscounted lease payments Finance Lease, Liability, Undiscounted Excess Amount Less: imputed interest Finance Lease, Liability Total lease liabilities Lessee, Operating Lease, Liability, to be Paid [Abstract] Operating Lease Lessee, Operating Lease, Liability, to be Paid, Year Three 2025 Lessee, Operating Lease, Liability, to be Paid, Year Four 2026 Lessee, Operating Lease, Liability, to be Paid, Year Five 2027 Lessee, Operating Lease, Liability, to be Paid, after Year Five Thereafter Lessee, Operating Lease, Liability, to be Paid Total undiscounted lease payments Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: imputed interest Lessee, Operating Lease, Liability, to be Paid, Year One 2023 Lessee, Operating Lease, Liability, to be Paid, Year Two 2024 Operating Lease, Liability Total lease liabilities Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Maximum number of shares of common stock that may be issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Options outstanding (in shares) Options outstanding at beginning of period (in shares) Options outstanding at end of period (in shares) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Unrecognized stock-based compensation cost, weighted-average period recognized (in years) Class of Warrant or Right, Exercise Price of Warrants or Rights Exercise price (in dollars per share) Class of Warrant or Right, Notice Period Notice period Class of Warrant or Right, Notice Period Sale Of Stock, Maximum Aggregate Offering Price Maximum value Sale Of Stock, Maximum Aggregate Offering Price Share-Based Compensation Arrangement By Share-based Payment Award, Purchase Period ESPP offering period Share-Based Compensation Arrangement By Share-based Payment Award, Purchase Period Stock Based Compensation Increase In Common Stock Issuance Percentage Shares of common stock reserved for issuance percentage Percentage increase in the number of authorized common shares for grant under the stock based compensation plan. Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Number of additional shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent ESPP purchase price of common stock, percent of market price Employee Stock Purchase Plan Number Of Offering Per Year ESPP number of offerings per year employee stock purchase plan number of offering per year Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Award expiration period (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Shares available to be granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted-average grant date fair value of options granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Common stock issued upon exercise of options aggregate intrinsic value Common Stock, Capital Shares Reserved for Future Issuance ESPP common stock reserved for issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate ESPP max contribution rate Shares Issued, Price Per Share Sale of shares under public offering (in dollars per share) Percentage of Outstanding Stock per Stockholder, Upon Notice, Maximum Percentage of outstanding stock per stockholder, upon notice, maximum Percentage of Outstanding Stock per Stockholder, Upon Notice, Maximum Percentage Of Outstanding Stock Per Stockholder, Maximum Percentage of outstanding stock per stockholder, maximum Percentage Of Outstanding Stock Per Stockholder, Maximum Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Unrecognized stock-based compensation cost (in dollars per share) Sale of Stock [Axis] Sale of Stock [Axis] Sale of Stock [Domain] Sale of Stock [Domain] Equity Offering Sales Agreement [Member] Equity Offering Sales Agreement Equity Offering Sales Agreement Plan Name [Axis] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] 2020 Employee Stock Purchase Plan [Member] 2020 Employee Stock Purchase Plan 2020 Employee Stock Purchase Plan Stock Incentive Plan Two Thousand Fourteen [Member] 2014 Plan Equity Incentive Plan Two Thousand Six [Member] Equity Incentive Plan 2006 Subsequent Event Type [Axis] Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event Award Type [Axis] Award Type [Axis] Award Type [Domain] Award Type [Domain] Employee Stock [Member] Shares issuable under 2020 ESPP Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Options outstanding at end of period, Aggregate intrinsic value (in dollars) Options outstanding at beginning of period, Aggregate intrinsic value (in dollars) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Options outstanding, Weighted average remaining contractual life (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Options exercisable, Weighted average remaining contractual life (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Options exercisable, Aggregate intrinsic value (in dollars) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Number of Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Options cancelled/forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Options exercisable, Number of options (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Options outstanding at beginning of period (in dollars per share) Options outstanding at end of period (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Options cancelled/forfeited (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Options exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Options granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Options exercisable, Weighted average exercise price (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Expected terms (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk free rate Restricted Stock Units (RSUs) [Member] Restricted stock units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Weighted Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Restricted stock units granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Non-vested beginning balance (in dollars per share) Non-vested ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Restricted stock units vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Restricted stock units forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward] Number of Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Non-vested ending balance (in shares) Non-vested beginning balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Restricted stock units forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Restricted stock units vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Restricted stock units granted (in shares) Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] General and Administrative Expense [Member] General and administrative expenses [Member] Research and Development Expense [Member] Research and development expenses [Member] Share-Based Payment Arrangement, Expense Stock-based compensation expense Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Share-Based Payment Arrangement, Option [Member] Outstanding stock options Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Securities excluded from computation of earnings per share (in shares) Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Statutory federal income tax rate Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent Stock-based compensation Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Change in valuation allowance Effective Income Tax Rate Reconciliation, Tax Credit, Percent Tax credits Effective Income Tax Rate Reconciliation, Percent Income tax recovery Income (Loss) from Continuing Operations before Income Taxes, Domestic U.S. Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Total Components of Deferred Tax Assets [Abstract] Deferred tax assets: Deferred Tax Assets, Tax Credit Carryforwards, Research Research and development deductions and credits Deferred Tax Assets, Operating Loss Carryforwards, Domestic U.S. net operating losses Deferred Tax Assets, Goodwill and Intangible Assets Intangibles Deferred Tax Assets, Lease Liability Lease liability Deferred Tax Assets, Lease Liability Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Stock-based compensation Deferred Tax Assets, Capitalized Research and Development Capitalized research and development Deferred Tax Assets, Capitalized Research and Development Deferred Tax Assets, Other Other Deferred Tax Assets, Gross Total deferred tax assets: Deferred Tax Assets, Net of Valuation Allowance Deferred tax assets, net of valuation allowance Components of Deferred Tax Liabilities [Abstract] Deferred income tax liabilities Deferred Tax Liabilities, Leasing Arrangements Right-of-use assets Deferred Tax Liabilities, Other Other Deferred Tax Liabilities, Gross Total deferred tax liabilities Deferred Tax Assets, Valuation Allowance Less: valuation allowance Deferred Tax Assets, Before Valuation Allowance Net deferred income tax assets Deferred Tax Assets, Before Valuation Allowance Income Taxes Disclosure [Table] Income Taxes Disclosure [Table] Income Taxes Disclosure Income Taxes Disclosure [Line Items] Income Taxes Disclosure [Line Items] Income Taxes Disclosure Operating Loss Carryforwards Net operating losses carried forward for tax purposes Operating Loss Carryforwards Subject To Expiration Operating loss carryforwards subject to expiration Operating loss carryforwards subject to expiration. Operating Loss Carryforwards Not Subject To Expiration Operating loss carryforwards not subject to expiration Operating loss carryforwards not subject to expiration. 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Industry Sector [Axis] Industry Sector [Axis] Industry Sector [Domain] Industry Sector [Domain] University Of Washington [Member] University Of Washington Schedule of Restructuring and Related Costs [Table] Schedule of Restructuring and Related Costs [Table] Restructuring Cost and Reserve [Line Items] Restructuring Cost and Reserve [Line Items] Restructuring Reserve Accrued at period end Payments for Restructuring Amounts Paid Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Number of positions eliminated, period percent Restructuring Charges Charges Property, Plant and Equipment, Disposals Property and equipment disposals Restructuring and Related Cost, Expected Cost Expected cost Restructuring Plan [Axis] Restructuring Plan [Axis] Restructuring Plan [Domain] Restructuring Plan [Domain] March2023 Restructuring Plan [Member] March2023 Restructuring Plan [Member] November 2022 Reductions [Member] November 2022 Reductions [Member] November 2022 Reductions Scenario [Axis] Scenario [Axis] Scenario [Domain] Scenario [Domain] Forecast [Member] Forecast [Member] Asset Class [Axis] Asset Class [Domain] Property, Plant and Equipment [Member] Property, Plant and Equipment [Member] Subsequent Event [Table] Subsequent Event [Table] Subsequent Event [Line Items] Subsequent Event [Line Items] Business Combination Reimbursement Of Expenses Business combination reimbursement of expenses Business combination reimbursement of expenses. Business Combination Termination Fee Business combination termination fee Business combination termination fee. Restructuring and Related Cost, Expected Cost, Non-Cash Expense Expected non-cash expense Restructuring and Related Cost, Expected Cost, Non-Cash Expense Agreement [Axis] Agreement [Domain] Merger Agreement [Member] Merger Agreement [Member] Legal Entity [Axis] Entity [Domain] Neoleukin [Member] Neoleukin [Member] Related Party [Axis] Related Party [Domain] Neurogene [Member] Neurogene [Member]