v3.24.0.1
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jul. 31, 2018
USD ($)
Aug. 31, 2022
USD ($)
shares
Mar. 31, 2022
USD ($)
Nov. 30, 2020
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Jun. 30, 2022
USD ($)
May 31, 2022
USD ($)
Nov. 30, 2021
USD ($)
Feb. 28, 2021
USD ($)
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Research and development         $ 758,759 $ 745,506 $ 2,475,596 $ 2,059,769 $ 2,672,836 $ 1,562,927        
Accrued expenses         2,594,199   2,594,199   1,175,705 1,685,409        
Other income         198,544 (702,002) 524,142 (208,765) (123,792) (15,399,738)        
Gain on reduction in liability               416,000 416,000          
Settlement of accrued expenses (in shares) | shares   3,682                        
Research and consulting agreement | Polytherapeutics                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Total amount of agreement                           $ 666,667
Monthly payments                           $ 20,833
Research and consulting agreement | Axella Research LLC                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Total amount of agreement $ 270,000                          
Research and development   $ 0                        
Number of agreements 3                          
Research and consulting agreement | Netherton Syndrome                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Research and development                 77,000 25,000        
Research and consulting agreement | Therapeutics Inc.                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Credit of prior expenses incurred         278,000                  
Research and development         155,000 423,000 1,113,000 904,000 1,200,000 340,000        
Research and consulting agreement | Scleroderma                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Total amount of agreement                       $ 610,000    
Research and development         85,000 173,000 361,000 250,000 276,000          
Consulting agreements | Axella Research LLC                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Accrued expenses                   194,000        
Consulting agreements | Investor Relations firm                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Monthly payments         14,000   14,000   14,000          
Accrued expenses                   584,000        
Other income     $ 416,000                      
Gain on reduction in liability     $ 168,000                      
Consulting fees         $ 0 $ 0 $ 0 $ 0 112,000 $ 70,000        
Consulting agreements | Netherton Syndrome                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Total amount of agreement                         $ 250,000  
Consulting agreements | Therapeutics Inc.                            
RESEARCH, CONSULTING AGREEMENTS AND COMMITMENTS                            
Initial term       3 years                    
Written termination notice period       90 days                    
Total amount of agreement                 $ 830,000   $ 4,400,000