Components of Net Deferred Tax Assets (Detail) - USD ($) $ in Thousands |
Dec. 31, 2023 |
Dec. 31, 2022 |
|---|---|---|
| Deferred tax assets: | ||
| Net operating loss carryforwards | $ 506,641 | $ 542,537 |
| Research and development credits | 77,007 | 78,804 |
| Capitalized research costs | 14,225 | 4,369 |
| Milestone Rights | 1,006 | 1,331 |
| Accrued expenses | 3,760 | 2,675 |
| Loss on purchase commitment | 22,806 | 23,117 |
| Non-qualified stock option expense | 3,559 | 7,686 |
| Capitalized patent costs | 6,720 | 8,058 |
| Other | 3,405 | 3,204 |
| Lease liability | 1,280 | 1,624 |
| Interest expense limitation | 2,782 | 10,991 |
| Depreciation | 21,134 | 22,157 |
| Deferred product revenue and costs | 346 | 370 |
| Sale of future royalties | 34,848 | |
| Total deferred tax assets | 699,519 | 706,923 |
| Valuation allowance | (698,228) | (705,034) |
| Net deferred tax assets | 1,291 | 1,889 |
| Deferred tax liabilities: | ||
| Right of use asset | (1,121) | (1,640) |
| Other prepaids | (176) | (249) |
| Total deferred tax liabilities | (1,297) | $ (1,889) |
| Net deferred tax assets | $ (6) |
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- Definition Deferred Tax Assets Capitalized Costs No definition available.
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- Definition Deferred Tax Assets Capitalized Research Expenses No definition available.
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- Definition Deferred tax assets interest expense limitation. No definition available.
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- Definition Deferred tax assets lease liabilities. No definition available.
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- Definition Deferred Tax Assets Loss on Purchase Commitment No definition available.
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- Definition Deferred Tax Assets Milestone Rights No definition available.
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- Definition Deferred tax assets product revenue and other. No definition available.
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- Definition Deferred tax assets sale of future royalties. No definition available.
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- Definition Deferred Tax Assets, Tax Deferred Expense (Accrual Adjustment) No definition available.
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- Definition Deferred tax liabilities right of use asset. No definition available.
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- References No definition available.
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- References No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount after allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences, classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences from provisions, reserves, allowances, and accruals, classified as other. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of deferred tax consequences attributable to taxable temporary differences derived from prepaid expenses. No definition available.
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