Stock-based awards (Tables)
|
12 Months Ended |
Dec. 31, 2023 |
| Share-Based Payment Arrangement [Abstract] |
|
| Schedule of assumptions used to determine grant-date fair value of stock options granted |
The assumptions that the Company used to determine the grant-date fair value of stock options granted to employees, directors and consultants as follows, presented on a weighted average basis:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Year Ended December 31, |
|
2023 |
|
2022 |
|
2021 |
Expected term (in years) |
|
5.95 |
|
|
|
|
5.30 |
|
|
|
|
5.77 |
|
|
Expected volatility |
|
81.89 |
|
% |
|
|
74.59 |
|
% |
|
|
72.17 |
|
% |
Weighted average risk-free interest rate |
|
4.19 |
|
% |
|
|
2.71 |
|
% |
|
|
1.19 |
|
% |
Expected dividend yield |
|
0.00 |
|
% |
|
|
0.00 |
|
% |
|
|
0.00 |
|
% |
|
| Summary of stock option activity |
The following table summarizes the Company’s stock option activity since December 31, 2022:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Weighted- |
|
|
Weighted- |
|
|
|
|
|
|
|
|
|
Average |
|
|
Average |
|
|
Aggregate |
|
|
|
|
|
|
Exercise |
|
|
remaining |
|
|
Intrinsic |
|
|
|
Number |
|
|
Price per |
|
|
contractual |
|
|
Value |
|
|
|
of Options |
|
|
Share |
|
|
term (years) |
|
|
(000's) |
|
Balance outstanding, December 31, 2022 |
|
|
5,780,004 |
|
|
$ |
18.88 |
|
|
|
7.80 |
|
|
$ |
207,611 |
|
Options granted |
|
|
1,720,882 |
|
|
$ |
28.29 |
|
|
|
|
|
|
|
Options exercised |
|
|
(593,959 |
) |
|
$ |
5.50 |
|
|
|
|
|
|
|
Options cancelled |
|
|
(6,950 |
) |
|
$ |
49.74 |
|
|
|
|
|
|
|
Balance outstanding, December 31, 2023 |
|
|
6,899,977 |
|
|
$ |
22.35 |
|
|
|
7.67 |
|
|
$ |
35,133 |
|
Vested and expected to vest, December 31, 2023 |
|
|
6,899,977 |
|
|
$ |
22.35 |
|
|
|
7.67 |
|
|
$ |
35,133 |
|
Exercisable, December 31, 2023 |
|
|
4,126,549 |
|
|
$ |
18.32 |
|
|
|
6.69 |
|
|
$ |
28,508 |
|
|
| Summary of stock-based compensation expense |
The following table summarizes the Company’s stock-based compensation expense during the years ended December 31, 2023, 2022 and 2021:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Year Ended December 31, |
|
|
|
2023 |
|
|
2022 |
|
|
2021 |
|
Classified within research and development expense |
|
$ |
|
7,579 |
|
|
$ |
|
8,096 |
|
|
$ |
|
3,054 |
|
Classified within general and administrative expense |
|
|
|
13,918 |
|
|
|
|
15,147 |
|
|
|
|
7,000 |
|
Total stock-based compensation expense |
|
$ |
|
21,497 |
|
|
$ |
|
23,243 |
|
|
$ |
|
10,054 |
|
|
| Summary of restricted stock activity |
The following table summarizes the Company’s RSUs activity since December 31, 2022:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Weighted- |
|
|
Weighted- |
|
|
|
|
|
|
|
|
|
Average |
|
|
Average |
|
|
Aggregate |
|
|
|
|
|
|
Grant Date |
|
|
remaining |
|
|
Intrinsic |
|
|
|
Underlying |
|
|
Fair Value per |
|
|
contractual |
|
|
Value |
|
|
|
shares |
|
|
Share |
|
|
term (years) |
|
|
(000's) |
|
Balance outstanding, December 31, 2022 |
|
|
129,131 |
|
|
$ |
42.95 |
|
|
|
2.07 |
|
|
$ |
7,076 |
|
Granted |
|
|
281,462 |
|
|
$ |
24.03 |
|
|
|
|
|
|
|
Vested |
|
|
(38,641 |
) |
|
$ |
43.94 |
|
|
|
|
|
|
|
Cancelled or forfeited |
|
|
— |
|
|
$ |
— |
|
|
|
|
|
|
|
Balance outstanding, December 31, 2023 |
|
|
371,952 |
|
|
$ |
28.53 |
|
|
|
1.98 |
|
|
$ |
8,685 |
|
|