v3.24.0.1
Stock-based awards (Tables)
12 Months Ended
Dec. 31, 2023
Share-Based Payment Arrangement [Abstract]  
Schedule of assumptions used to determine grant-date fair value of stock options granted

The assumptions that the Company used to determine the grant-date fair value of stock options granted to employees, directors and consultants as follows, presented on a weighted average basis:

 

 

Year Ended December 31,

 

2023

 

2022

 

2021

Expected term (in years)

 

5.95

 

 

 

 

5.30

 

 

 

 

5.77

 

 

Expected volatility

 

81.89

 

%

 

 

74.59

 

%

 

 

72.17

 

%

Weighted average risk-free interest rate

 

4.19

 

%

 

 

2.71

 

%

 

 

1.19

 

%

Expected dividend yield

 

0.00

 

%

 

 

0.00

 

%

 

 

0.00

 

%

Summary of stock option activity

The following table summarizes the Company’s stock option activity since December 31, 2022:

 

 

 

 

 

 

Weighted-

 

 

Weighted-

 

 

 

 

 

 

 

 

 

Average

 

 

Average

 

 

Aggregate

 

 

 

 

 

 

Exercise

 

 

remaining

 

 

Intrinsic

 

 

 

Number

 

 

Price per

 

 

contractual

 

 

Value

 

 

 

of Options

 

 

Share

 

 

term (years)

 

 

(000's)

 

Balance outstanding, December 31, 2022

 

 

5,780,004

 

 

$

18.88

 

 

 

7.80

 

 

$

207,611

 

Options granted

 

 

1,720,882

 

 

$

28.29

 

 

 

 

 

 

 

Options exercised

 

 

(593,959

)

 

$

5.50

 

 

 

 

 

 

 

Options cancelled

 

 

(6,950

)

 

$

49.74

 

 

 

 

 

 

 

Balance outstanding, December 31, 2023

 

 

6,899,977

 

 

$

22.35

 

 

 

7.67

 

 

$

35,133

 

Vested and expected to vest, December 31, 2023

 

 

6,899,977

 

 

$

22.35

 

 

 

7.67

 

 

$

35,133

 

Exercisable, December 31, 2023

 

 

4,126,549

 

 

$

18.32

 

 

 

6.69

 

 

$

28,508

 

Summary of stock-based compensation expense

The following table summarizes the Company’s stock-based compensation expense during the years ended December 31, 2023, 2022 and 2021:

 

 

Year Ended December 31,

 

 

 

2023

 

 

2022

 

 

2021

 

Classified within research and development expense

 

$

 

7,579

 

 

$

 

8,096

 

 

$

 

3,054

 

Classified within general and administrative expense

 

 

 

13,918

 

 

 

 

15,147

 

 

 

 

7,000

 

Total stock-based compensation expense

 

$

 

21,497

 

 

$

 

23,243

 

 

$

 

10,054

 

Summary of restricted stock activity

The following table summarizes the Company’s RSUs activity since December 31, 2022:

 

 

 

 

 

 

Weighted-

 

 

Weighted-

 

 

 

 

 

 

 

 

 

Average

 

 

Average

 

 

Aggregate

 

 

 

 

 

 

Grant Date

 

 

remaining

 

 

Intrinsic

 

 

 

Underlying

 

 

Fair Value per

 

 

contractual

 

 

Value

 

 

 

shares

 

 

Share

 

 

term (years)

 

 

(000's)

 

Balance outstanding, December 31, 2022

 

 

129,131

 

 

$

42.95

 

 

 

2.07

 

 

$

7,076

 

Granted

 

 

281,462

 

 

$

24.03

 

 

 

 

 

 

 

Vested

 

 

(38,641

)

 

$

43.94

 

 

 

 

 

 

 

Cancelled or forfeited

 

 

—

 

 

$

—

 

 

 

 

 

 

 

Balance outstanding, December 31, 2023

 

 

371,952

 

 

$

28.53

 

 

 

1.98

 

 

$

8,685