The amount of aggregate milestone payments upon the achievement of specified clinical and regulatory milestones.

No definition available.

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Amount of fair value of anti-dilution of right liability.

+ References

No definition available.

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- Definition

Obligation for payment in connection with dosing with first patient phase three synchrony program.

+ References

No definition available.

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- Definition

The amount of payment in connection with dosing of the first patient in our Phase three a clinical trial for marketing approval.

+ References

No definition available.

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The amount of payment in connection with dosing of the first patient in our Phase two a clinical trial.

+ References

No definition available.

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- Definition

Amount of upfront payment made in exchange for the rights.

+ References

No definition available.

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- Definition

The equity interest of noncontrolling shareholders, partners or other equity holders in consolidated entity.

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No definition available.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

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- Definition

The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Number of new stock issued during the period.

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Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.

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Amgen license agreement (Details) - USD ($)	1 Months Ended		3 Months Ended	12 Months Ended
Amgen license agreement (Details) - USD ($)	Nov. 30, 2018	Jun. 30, 2018	Sep. 30, 2019	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Share Issued value under agreement					$ 24,647,000
Research and development expense				$ 141,798,000	85,284,000	$ 81,759,000
Amgen Agreement
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Initial fair value of the anti-dilution right liability	$ 7,404,000
Payment for clinical trail			$ 2,500,000
Obligation for payment in connection with dosing of the first patient			7,500,000
Amgen Agreement \| Maximum
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Aggregate milestone payments upon the achievement of specified commercial milestones			75,000,000
Payment in connection with dosing of the first patient			$ 30,000,000
Amgen Agreement \| Research and development expense
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and development expense				$ 7,500,000	$ 0	$ 0
Amgen Agreement \| Amgen
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Upfront payment		$ 5,000,000
Amgen Agreement \| Series A Preferred Stock
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Share Issued under agreement	3,205,128
Amgen Agreement \| Series A Preferred Stock \| Amgen
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Share Issued under agreement		2,653,333
Share Issued value under agreement		$ 1,353,000
Ownership Interest [Member] \| Amgen Agreement \| Amgen
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Ownership interest of the outstanding shares (as a percent)		10.00%