v3.24.0.1
Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Balance at Dec. 31, 2020 $ 9 $ 1,411,286 $ 4,259 $ (929,318) $ 486,236
Balance (in shares) at Dec. 31, 2020 86,223,000        
Issuance of common stock upon exercise of stock options   11,816     11,816
Issuance of common stock upon exercise of stock options (in shares) 1,165,000        
Issuance of common stock under employee stock purchase plan   13,550     13,550
Issuance of common stock under employee stock purchase plan (in shares) 186,000        
Issuance of common stock for IPR&D   30,601     30,601
Issuance of common stock for IPR&D (in shares) 274,000        
Vesting of restricted stock units (in shares) 2,117,000        
Stock based compensation   115,219     115,219
Unrealized gain (loss) on available-for sale securities     (6,546)   (6,546)
Cumulative-effect adjustment upon adoption   (82,876)   6,198 (76,678)
Issuance of common stock for public offering, net $ 1 550,821     550,822
Issuance of common stock for public offering, net (in shares) 5,175,000        
Net loss       (471,716) (471,716)
Balance at Dec. 31, 2021 $ 10 2,050,417 (2,287) (1,394,836) 653,304
Balance (in shares) at Dec. 31, 2021 95,140,000        
Issuance of common stock upon exercise of stock options   6,411     6,411
Issuance of common stock upon exercise of stock options (in shares) 828,000        
Issuance of common stock under employee stock purchase plan   13,037     13,037
Issuance of common stock under employee stock purchase plan (in shares) 437,000        
Issuance of common stock for IPR&D   9,290     9,290
Issuance of common stock for IPR&D (in shares) 225,000        
Vesting of restricted stock units (in shares) 1,480,000        
Stock based compensation   152,384     152,384
Unrealized gain (loss) on available-for sale securities     (14,075)   (14,075)
Issuance of common stock for public offering, net $ 1 433,191     433,192
Issuance of common stock for public offering, net (in shares) 13,145,000        
Net loss       (547,799) (547,799)
Balance at Dec. 31, 2022 $ 11 2,664,730 (16,362) (1,942,635) $ 705,744
Balance (in shares) at Dec. 31, 2022 111,255,000       111,255,000
Issuance of common stock upon exercise of stock options   3,892     $ 3,892
Issuance of common stock upon exercise of stock options (in shares) 298,000        
Issuance of common stock under employee stock purchase plan   15,128     15,128
Issuance of common stock under employee stock purchase plan (in shares) 392,000        
Issuance of common stock for IPR&D $ 336 14,435     14,435
Vesting of restricted stock units (in shares) 2,401,000        
Stock based compensation   192,437     192,437
Issuance of common stock for bonuses   19,774     19,774
Issuance of common stock for bonuses (in shares) 349,000        
Unrealized gain (loss) on available-for sale securities     13,277   13,277
Issuance of common stock for public offering, net   235,441     235,441
Issuance of common stock for public offering, net (in shares) 4,550,000        
Net loss       (434,801) (434,801)
Balance at Dec. 31, 2023 $ 11 $ 3,145,837 $ (3,085) $ (2,377,436) $ 765,327
Balance (in shares) at Dec. 31, 2023 119,581,000       119,581,000