Capitalized research and development costs amortization period.

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Deferred tax assets, tax credit carryforwards, research expiration year.

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Income tax.

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Operating loss carryforwards expiration year.

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Percentage of change in ownership.

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No definition available.

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Period of change in ownership.

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No definition available.

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- Definition

Research and development costs capitalized.

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- Definition

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards that are not subject to expiration dates.

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No definition available.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards that are subject to expiration dates.

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No definition available.

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- Definition

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards.

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Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Amount of increase reasonably possible in the next twelve months for the unrecognized tax benefit.

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Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

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Amount accrued for interest on an underpayment of income taxes and penalties related to a tax position claimed or expected to be claimed in the tax return.

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Income Tax - Additional Information (Detail) - USD ($)	12 Months Ended
Income Tax - Additional Information (Detail) - USD ($)	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Income Tax [Line Items]
Income tax (benefit) provision	$ 0	$ 0	$ 0
Valuation allowance	107,989,000	95,484,000
Capitalized R&D costs	$ 44,200,000	38,800,000
Period of change in ownership	3 years
Percentage of change in ownership	50.00%
Unrecognized tax benefits, income tax penalties and interest accrued	$ 0	$ 0	$ 0
Change in unrecognized tax benefits	$ 0
Federal [Member]
Income Tax [Line Items]
Amortization period of capitalized R&D costs	5 years
NOLs carryforwards	$ 257,400,000
NOLs carryforwards not subject to expiration	144,900,000
NOLs carryforwards subject to expiration	$ 112,500,000
NOLs carryforwards expiration year	2025
Research and development credit carryforward	$ 9,300,000
Research and development credit carryforward expiration year	2026
Federal [Member] \| Orphan Drug Credits [Member]
Income Tax [Line Items]
Research and development credit carryforward	$ 400,000
Research and development credit carryforward expiration year	2035
State [Member]
Income Tax [Line Items]
NOLs carryforwards subject to expiration	$ 225,300,000
NOLs carryforwards expiration year	2025
Research and development credit carryforward	$ 5,800,000
Foreign [Member]
Income Tax [Line Items]
Amortization period of capitalized R&D costs	15 years
NOLs carryforwards not subject to expiration	$ 9,400,000