Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
Mar. 31, 2024	Mar. 31, 2023
Total revenue	$ 50	$ 2,169
Operating expenses:
Research and development	64,114	44,756
General and administrative	17,464	13,738
Total operating expenses	81,578	58,494
Loss from operations	(81,528)	(56,325)
Other income (expense):
Interest income	7,165	6,690
Other expense, net	(77)	(141)
Total other income, net	7,088	6,549
Loss before income taxes	(74,440)	(49,776)
Benefit from income taxes	(2,201)	(2,912)
Net loss	$ (72,239)	$ (46,864)
Basic (in dollars per share)	$ (1.34)	$ (0.89)
Diluted (in dollars per share)	$ (1.34)	$ (0.89)
Weighted-average ordinary shares outstanding used in per share calculations- basic (in shares)	53,714	52,501
Weighted-average ordinary shares outstanding used in per share calculations- diluted (in shares)	53,714	52,501
Collaboration revenue
Total revenue	$ 0	$ 2,119
Revenue from license and intellectual property
Total revenue	$ 50	$ 50

The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.

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Namespace Prefix:	us-gaap_
Data Type:	dtr-types:perShareItemType
Balance Type:	na
Period Type:	duration

- Definition

The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.