| Financial instruments measured at fair value |
Financial assets and liabilities subject to fair value measurements on a recurring basis and the level of inputs used in such measurements by major security type are presented in the following table: | | | | | | | | | | | | | | | | | | | | | | | | | | March 31, 2024 | | | Level 1 | | Level 2 | | Level 3 | | Total | | Assets: | | | | | | | | Money market funds(1) | $ | 186,744 | | | $ | — | | | $ | — | | | $ | 186,744 | | | U.S. Treasury securities | 31,812 | | | — | | | — | | | 31,812 | | | Commercial paper | — | | | 30,828 | | | — | | | 30,828 | | | Corporate debt securities | — | | | 25,490 | | | — | | | 25,490 | | | Government-related debt securities | — | | | 23,604 | | | — | | | 23,604 | | | Common stock in LianBio | 46 | | | — | | | — | | | 46 | | | | | | | | | | | Total assets measured at fair value | $ | 218,602 | | | $ | 79,922 | | | $ | — | | | $ | 298,524 | | (1) This balance includes cash requirements settled on a nightly basis. |
| | | | | | | | | | | | | | | | | | | | | | | | | December 31, 2023 | | Level 1 | | Level 2 | | Level 3 | | Total | | Assets: | | | | | | | | Money market funds(1) | $ | 224,947 | | | $ | — | | | $ | — | | | $ | 224,947 | | | | | | | | | | | | | | | | | | | | | | | | | | | Government-related debt securities | — | | | 2,495 | | | — | | | 2,495 | | | Common stock in LianBio | 631 | | | — | | | — | | | 631 | | | Equity warrants (for LianBio shares) | — | | | — | | | 225 | | | 225 | | | Total assets measured at fair value | $ | 225,578 | | | $ | 2,495 | | | $ | 225 | | | $ | 228,298 | | (1) This balance includes cash requirements settled on a nightly basis. |
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| Changes in fair value of equity warrants |
The estimated fair value of the equity warrants were remeasured each reporting period with adjustments reported within other income (expense) on the accompanying Condensed Statements of Operations and Comprehensive Loss, until exercised, expired or terminated. These equity warrants are valued in the accompanying Condensed Financial Statements as follows: | | | | | | | | | | | Value of equity warrants | | Fair value as of December 31, 2023 | | $ | 225 | | | Remeasurement of equity warrants prior to termination | | (201) | | | Termination of equity warrants | | (24) | | | Fair value as of March 31, 2024 | | $ | — | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | Value of equity warrants | | Fair value as of December 31, 2022 | | $ | 108 | | | | | | Remeasurement of equity warrants | | (17) | | | Fair value as of March 31, 2023 | | $ | 91 | | | | | | | | | | | | | | | | | | | |
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| Summary of estimated value of cash, cash equivalents, marketable securities, and equity securities |
The fair value and amortized cost of cash equivalents and available-for-sale investments by major security type are presented in the following table: | | | | | | | | | | | | | | | | | | | | | | | | | March 31, 2024 | | Amortized cost | | Unrealized gains | | Unrealized losses | | Estimated fair value | | Cash equivalents: | | | | | | | | Money market funds(1) | $ | 186,744 | | | $ | — | | | $ | — | | | $ | 186,744 | | | U.S. Treasury securities | 3,484 | | | — | | | — | | | 3,484 | | | | | | | | | | | Commercial paper | 3,478 | | | — | | | (1) | | | 3,477 | | | Total cash equivalents | $ | 193,706 | | | $ | — | | | $ | (1) | | | $ | 193,705 | | | | | | | | | | | Marketable securities: | | | | | | | | | U.S. Treasury securities | $ | 28,341 | | | $ | — | | | $ | (13) | | | $ | 28,328 | | | Commercial paper | 27,374 | | | — | | | (23) | | | 27,351 | | | Corporate debt securities | 25,509 | | | — | | | (19) | | | 25,490 | | | Government-related debt securities | 23,613 | | | 4 | | | (13) | | | 23,604 | | | Common stock in LianBio | 1,108 | | | — | | | (1,062) | | | 46 | | | Total marketable securities | $ | 105,945 | | | $ | 4 | | | $ | (1,130) | | | $ | 104,819 | |
(1) This balance includes cash requirements settled on a nightly basis. | | | | | | | | | | | | | | | | | | | | | | | | | December 31, 2023 | | Amortized cost | | Unrealized gains | | Unrealized losses | | Estimated fair value | | Cash equivalents: | | | | | | | | Money market funds(1) | $ | 224,947 | | | $ | — | | | $ | — | | | $ | 224,947 | | | | | | | | | | | | | | | | | | | Total cash equivalents | $ | 224,947 | | | $ | — | | | $ | — | | | $ | 224,947 | | | | | | | | | | | Marketable securities: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Government-related debt securities | $ | 2,496 | | | $ | — | | | $ | (1) | | | $ | 2,495 | | | Total marketable securities | $ | 2,496 | | | $ | — | | | $ | (1) | | | $ | 2,495 | | | | | | | | | | | Long-term investments: | | | | | | | | | Common stock in LianBio | $ | 1,108 | | | $ | — | | | $ | (477) | | | $ | 631 | | | Total long-term investments | $ | 1,108 | | | $ | — | | | $ | (477) | | | $ | 631 | |
(1 ) This balance includes cash requirements settled on a nightly basis.
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