Share-Based Compensation (Tables)
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6 Months Ended |
Jun. 30, 2024 |
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| Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
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| Schedule of Share Option Activity |
| | | | | | | | | | | | | | | | | | | | Weighted- | | | | | | | Weighted- | | | Average | | | | | | | Average | | | Remaining | | | | | Number of | | Exercise | | | Contractual | | | | | Options | | Price | | | Term (years) | | Outstanding at December 31, 2023 | | | 8,226,707 | | $ | 12.96 | | | 6.35 | years | Granted | | | 365,100 | | $ | 6.16 | | | | | Exercised | | | — | | $ | — | | | | | Forfeited | | | (254,429) | | $ | 16.24 | | | | | Outstanding at June 30, 2024 | | | 8,337,378 | | $ | 12.58 | | | 5.98 | years | Options exercisable at June 30, 2024 | | | 6,468,590 | | $ | 12.98 | | | 5.32 | years | Options vested and expected to vest at June 30, 2024 | | | 8,336,478 | | $ | 12.58 | | | 5.98 | years | Aggregate intrinsic value of options outstanding as of June 30, 2024 | | $ | 540 | | | | | | | | Aggregate intrinsic value of options exercisable as of June 30, 2024 | | $ | 540 | | | | | | | |
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| Schedule of Inputs Used in Determining Fair Value of Share Options |
| | | | | | | 2024 | | 2023 | Risk-free interest rate | | 4.04 - 4.17% | | 3.91 - 4.11% | Expected volatility | | 67% | | 72% | Expected dividend yield | | 0% | | 0% | Expected term (in years) | | 3.6 - 6.1 | | 6.1 |
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| Schedule of Restricted Share Unit (RSU) Activity |
| | | | | | | | | | | | Weighted- | | | | Number of | | Average | | | | Restricted | | Grant Date | | | | Share Units | | Fair Value | Outstanding at December 31, 2023 | | | 2,661,250 | | $ | 15.24 | Granted | | | 2,638,500 | | $ | 5.97 | Vested | | | (942,500) | | $ | 18.45 | Outstanding at June 30, 2024 | | | 4,357,250 | | $ | 8.93 |
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| Schedule of Share-Based Compensation Expense |
| | | | | | | | | Three-Month Periods Ended June 30, | | | 2024 | | 2023 | Research and development | | $ | 2,832 | | $ | 3,293 | General and administrative | | | 2,978 | | | 3,978 | Total share-based compensation | | $ | 5,810 | | $ | 7,271 |
| | | | | | | | | Six-Month Periods Ended June 30, | | | 2024 | | 2023 | Research and development | | $ | 5,707 | | $ | 6,319 | General and administrative | | | 7,063 | | | 7,384 | Total share-based compensation | | $ | 12,770 | | $ | 13,703 |
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| Employee Stock Option |
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| Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
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| Schedule of Share-Based Compensation Expense |
| | | | | | | | | Three-Month Periods Ended June 30, | | | 2024 | | 2023 | Research and development | | $ | 1,579 | | $ | 2,227 | General and administrative | | | 1,024 | | | 1,356 | Total share-based compensation | | $ | 2,603 | | $ | 3,583 |
| | | | | | | | | Six-Month Periods Ended June 30, | | | 2024 | | 2023 | Research and development | | $ | 3,214 | | $ | 4,273 | General and administrative | | | 2,077 | | | 2,539 | Total share-based compensation | | $ | 5,291 | | $ | 6,812 |
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| Restricted Share Units |
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| Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
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| Schedule of Share-Based Compensation Expense |
| | | | | | | | | Three-Month Periods Ended June 30, | | | 2024 | | 2023 | Research and development | | $ | 1,253 | | $ | 1,066 | General and administrative | | | 1,954 | | | 2,622 | Total share-based compensation | | $ | 3,207 | | $ | 3,688 |
| | | | | | | | | Six-Month Periods Ended June 30, | | | 2024 | | 2023 | Research and development | | $ | 2,493 | | $ | 2,046 | General and administrative | | | 4,986 | | | 4,845 | Total share-based compensation | | $ | 7,479 | | $ | 6,891 |
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