Exhibit 107
Calculation of Filing Fee Table
Form S-1
(Form Type)
Upstream Bio, Inc.
(Exact Name of Registrant as Specified in its Charter)
Table 1: Newly Registered Securities
| Security Type |
Security Class Title | Fee Calculation Rule |
Amount Registered |
Proposed Maximum Offering Price Per Unit |
Proposed Maximum Aggregate Offering Price(1) |
Fee Rate |
Amount of Registration Fee | |||||||||
| Fees to be Paid |
Equity | Common Stock, par value $0.001 per share | 457(a) | 14,375,000(1) | $17.00(2) | $244,375,000 | $0.00015310 | $22,103.81(3) | ||||||||
| Fees Previously Paid | Equity | Common Stock, $0.001 par value per share | 457(a) | $100,000,000 | $0.00014760 | $14,760.00 | ||||||||||
| Total Offering Amounts | $244,375,000 | $36,863.81 | ||||||||||||||
| Total Fees Previously Paid | $14,760.00 | |||||||||||||||
| Total Fee Offsets | — | |||||||||||||||
| Net Fee Due | $22,103.81 | |||||||||||||||
| (1) | Includes 1,875,000 shares that the underwriters have the option to purchase. |
| (2) | Estimated solely for the purpose of computing the registration fee in accordance with Rule 457(a) under the Securities Act of 1933, as amended. |
| (3) | This registration fee only includes the payment of $22,103.81 for an additional $144,375,000 of shares, as the registrant previously paid $14,760.00 for the registration of $100,000,000 of shares under the Securities and Exchange Commission’s prior fee rate in effect until September 30, 2024. |