Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands |
Total |
Equity Financing |
At The Market Financing |
Common stock |
Common stock
Equity Financing
|
Common stock
At The Market Financing
|
Additional paid-in capital |
Additional paid-in capital
Equity Financing
|
Additional paid-in capital
At The Market Financing
|
Accumulated other comprehensive income (loss) |
Accumulated deficit |
| Beginning balance (in shares) at Nov. 30, 2022 |
|
|
|
47,172,299
|
|
|
|
|
|
|
|
| Beginning balance at Nov. 30, 2022 |
$ 303,696
|
|
|
$ 47
|
|
|
$ 709,220
|
|
|
$ (4,319)
|
$ (401,252)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
8,768
|
|
|
|
|
|
|
|
| Exercise of stock options |
28
|
|
|
|
|
|
28
|
|
|
|
|
| Vesting of restricted stock units (in shares) |
|
|
|
98,571
|
|
|
|
|
|
|
|
| Vesting of early exercised stock options |
31
|
|
|
|
|
|
31
|
|
|
|
|
| Issuance under employee stock purchase plan (in shares) |
|
|
|
165,215
|
|
|
|
|
|
|
|
| Issuance under employee stock purchase plan |
1,453
|
|
|
|
|
|
1,453
|
|
|
|
|
| Stock-based compensation |
8,505
|
|
|
|
|
|
8,505
|
|
|
|
|
| Unrealized gain on available-for-sale marketable securities |
1,072
|
|
|
|
|
|
|
|
|
1,072
|
|
| Net loss |
(40,733)
|
|
|
|
|
|
|
|
|
|
(40,733)
|
| Ending balance (in shares) at Feb. 28, 2023 |
|
|
|
47,444,853
|
|
|
|
|
|
|
|
| Ending balance at Feb. 28, 2023 |
274,052
|
|
|
$ 47
|
|
|
719,237
|
|
|
(3,247)
|
(441,985)
|
| Beginning balance (in shares) at Nov. 30, 2022 |
|
|
|
47,172,299
|
|
|
|
|
|
|
|
| Beginning balance at Nov. 30, 2022 |
303,696
|
|
|
$ 47
|
|
|
709,220
|
|
|
(4,319)
|
(401,252)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Net loss |
(101,992)
|
|
|
|
|
|
|
|
|
|
|
| Ending balance (in shares) at Aug. 31, 2023 |
|
|
|
48,503,768
|
|
|
|
|
|
|
|
| Ending balance at Aug. 31, 2023 |
233,817
|
|
|
$ 49
|
|
|
738,240
|
|
|
(1,228)
|
(503,244)
|
| Beginning balance (in shares) at Feb. 28, 2023 |
|
|
|
47,444,853
|
|
|
|
|
|
|
|
| Beginning balance at Feb. 28, 2023 |
$ 274,052
|
|
|
$ 47
|
|
|
719,237
|
|
|
(3,247)
|
(441,985)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Exercise of pre-funded warrants (in shares) |
148,497
|
|
|
|
|
|
|
|
|
|
|
| Exercise of pre-funded warrants |
$ 1
|
|
|
$ 1
|
|
|
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
5,597
|
|
|
|
|
|
|
|
| Exercise of stock options |
24
|
|
|
|
|
|
24
|
|
|
|
|
| Vesting of restricted stock units (in shares) |
|
|
|
32,261
|
|
|
|
|
|
|
|
| Vesting of early exercised stock options |
31
|
|
|
|
|
|
31
|
|
|
|
|
| Stock-based compensation |
8,746
|
|
|
|
|
|
8,746
|
|
|
|
|
| Unrealized gain on available-for-sale marketable securities |
1,344
|
|
|
|
|
|
|
|
|
1,344
|
|
| Net loss |
(24,277)
|
|
|
|
|
|
|
|
|
|
(24,277)
|
| Ending balance (in shares) at May. 31, 2023 |
|
|
|
47,631,208
|
|
|
|
|
|
|
|
| Ending balance at May. 31, 2023 |
$ 259,921
|
|
|
$ 48
|
|
|
728,038
|
|
|
(1,903)
|
(466,262)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Exercise of pre-funded warrants (in shares) |
568,863
|
|
|
|
|
|
|
|
|
|
|
| Exercise of pre-funded warrants |
$ 1
|
|
|
$ 1
|
|
|
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
101,219
|
|
|
|
|
|
|
|
| Exercise of stock options |
927
|
|
|
|
|
|
927
|
|
|
|
|
| Vesting of restricted stock units (in shares) |
|
|
|
100,729
|
|
|
|
|
|
|
|
| Vesting of early exercised stock options |
29
|
|
|
|
|
|
29
|
|
|
|
|
| Issuance under employee stock purchase plan (in shares) |
|
|
|
101,749
|
|
|
|
|
|
|
|
| Issuance under employee stock purchase plan |
776
|
|
|
|
|
|
776
|
|
|
|
|
| Stock-based compensation |
8,470
|
|
|
|
|
|
8,470
|
|
|
|
|
| Unrealized gain on available-for-sale marketable securities |
675
|
|
|
|
|
|
|
|
|
675
|
|
| Net loss |
(36,982)
|
|
|
|
|
|
|
|
|
|
(36,982)
|
| Ending balance (in shares) at Aug. 31, 2023 |
|
|
|
48,503,768
|
|
|
|
|
|
|
|
| Ending balance at Aug. 31, 2023 |
233,817
|
|
|
$ 49
|
|
|
738,240
|
|
|
(1,228)
|
(503,244)
|
| Beginning balance (in shares) at Nov. 30, 2023 |
|
|
|
48,718,552
|
|
|
|
|
|
|
|
| Beginning balance at Nov. 30, 2023 |
200,493
|
|
|
$ 49
|
|
|
746,299
|
|
|
(655)
|
(545,200)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
|
75,362
|
|
|
|
|
|
|
|
| Exercise of stock options |
355
|
|
|
|
|
|
355
|
|
|
|
|
| Vesting of restricted stock units (in shares) |
|
|
|
171,030
|
|
|
|
|
|
|
|
| Vesting of early exercised stock options |
21
|
|
|
|
|
|
21
|
|
|
|
|
| Repurchase of unvested early exercised stock (in shares) |
|
|
|
(1,548)
|
|
|
|
|
|
|
|
| Issuance under employee stock purchase plan (in shares) |
|
|
|
173,558
|
|
|
|
|
|
|
|
| Issuance under employee stock purchase plan |
1,269
|
|
|
|
|
|
1,269
|
|
|
|
|
| Stock-based compensation |
7,823
|
|
|
|
|
|
7,823
|
|
|
|
|
| Unrealized gain on available-for-sale marketable securities |
305
|
|
|
|
|
|
|
|
|
305
|
|
| Net loss |
(41,518)
|
|
|
|
|
|
|
|
|
|
(41,518)
|
| Ending balance (in shares) at Feb. 29, 2024 |
|
|
|
49,136,954
|
|
|
|
|
|
|
|
| Ending balance at Feb. 29, 2024 |
168,748
|
|
|
$ 49
|
|
|
755,767
|
|
|
(350)
|
(586,718)
|
| Beginning balance (in shares) at Nov. 30, 2023 |
|
|
|
48,718,552
|
|
|
|
|
|
|
|
| Beginning balance at Nov. 30, 2023 |
200,493
|
|
|
$ 49
|
|
|
746,299
|
|
|
(655)
|
(545,200)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Net loss |
(135,020)
|
|
|
|
|
|
|
|
|
|
|
| Ending balance (in shares) at Aug. 31, 2024 |
|
|
|
67,083,523
|
|
|
|
|
|
|
|
| Ending balance at Aug. 31, 2024 |
376,856
|
|
|
$ 67
|
|
|
1,056,665
|
|
|
344
|
(680,220)
|
| Beginning balance (in shares) at Feb. 29, 2024 |
|
|
|
49,136,954
|
|
|
|
|
|
|
|
| Beginning balance at Feb. 29, 2024 |
168,748
|
|
|
$ 49
|
|
|
755,767
|
|
|
(350)
|
(586,718)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Issuance of common stock and pre-funded warrants, net of issuance costs (in shares) |
|
|
|
|
11,916,667
|
3,194,809
|
|
|
|
|
|
| Issuance of common stock and pre-funded warrants, net of issuance costs |
|
$ 188,732
|
$ 48,469
|
|
$ 12
|
$ 3
|
|
$ 188,720
|
$ 48,466
|
|
|
| Exercise of stock options (in shares) |
|
|
|
24,108
|
|
|
|
|
|
|
|
| Exercise of stock options |
216
|
|
|
|
|
|
216
|
|
|
|
|
| Vesting of restricted stock units (in shares) |
|
|
|
83,997
|
|
|
|
|
|
|
|
| Vesting of early exercised stock options |
12
|
|
|
|
|
|
12
|
|
|
|
|
| Stock-based compensation |
8,847
|
|
|
|
|
|
8,847
|
|
|
|
|
| Unrealized gain on available-for-sale marketable securities |
215
|
|
|
|
|
|
|
|
|
215
|
|
| Net loss |
(44,546)
|
|
|
|
|
|
|
|
|
|
(44,546)
|
| Ending balance (in shares) at May. 31, 2024 |
|
|
|
64,356,535
|
|
|
|
|
|
|
|
| Ending balance at May. 31, 2024 |
370,693
|
|
|
$ 64
|
|
|
1,002,028
|
|
|
(135)
|
(631,264)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
|
|
| Issuance of common stock and pre-funded warrants, net of issuance costs (in shares) |
|
|
|
|
|
2,145,000
|
|
|
|
|
|
| Issuance of common stock and pre-funded warrants, net of issuance costs |
|
|
$ 41,980
|
|
|
$ 2
|
|
|
$ 41,978
|
|
|
| Exercise of stock options (in shares) |
|
|
|
281,291
|
|
|
|
|
|
|
|
| Exercise of stock options |
3,035
|
|
|
$ 1
|
|
|
3,034
|
|
|
|
|
| Vesting of restricted stock units (in shares) |
|
|
|
197,777
|
|
|
|
|
|
|
|
| Issuance under employee stock purchase plan (in shares) |
|
|
|
102,920
|
|
|
|
|
|
|
|
| Issuance under employee stock purchase plan |
863
|
|
|
|
|
|
863
|
|
|
|
|
| Stock-based compensation |
8,762
|
|
|
|
|
|
8,762
|
|
|
|
|
| Unrealized gain on available-for-sale marketable securities |
479
|
|
|
|
|
|
|
|
|
479
|
|
| Net loss |
(48,956)
|
|
|
|
|
|
|
|
|
|
(48,956)
|
| Ending balance (in shares) at Aug. 31, 2024 |
|
|
|
67,083,523
|
|
|
|
|
|
|
|
| Ending balance at Aug. 31, 2024 |
$ 376,856
|
|
|
$ 67
|
|
|
$ 1,056,665
|
|
|
$ 344
|
$ (680,220)
|