v3.24.3
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Revenue:        
Revenue $ 112,214 $ 67,046 $ 300,703 $ 186,864
Costs and operating expenses:        
Cost of goods sold 20,109 9,088 43,014 23,823
Collaboration expenses 29,307 17,311 80,122 39,585
Research and development 26,057 17,106 76,408 56,045
Selling, general and administrative 46,399 34,468 127,476 92,688
Total operating expenses 121,872 77,973 327,020 212,141
Loss from operations (9,658) (10,927) (26,317) (25,277)
Other income 2,457 2,428 7,144 6,175
Loss before income taxes (7,201) (8,499) (19,173) (19,102)
Benefit (provision) for income taxes (5,492) (5,356) (15,132) 7,949
Net loss $ (12,693) $ (13,855) $ (34,305) $ (11,153)
Net loss per share attributable to ordinary shareholders, basic $ (0.18) $ (0.20) $ (0.48) $ (0.16)
Net loss per share attributable to ordinary shareholders, diluted $ (0.18) $ (0.20) $ (0.48) $ (0.16)
Weighted average ordinary shares outstanding, basic 71,726,685 70,186,016 71,123,658 69,953,591
Weighted average ordinary shares outstanding, diluted 71,726,685 70,186,016 71,123,658 69,953,591
Comprehensive loss:        
Net loss $ (12,693) $ (13,855) $ (34,305) $ (11,153)
Other comprehensive income (loss):        
Unrealized gain (loss) on short-term investments and currency translation adjustments, net of tax 89 (14) (47) (45)
Total other comprehensive income (loss) 89 (14) (47) (45)
Total comprehensive loss (12,604) (13,869) (34,352) (11,198)
Product revenue, net        
Revenue:        
Revenue $ 112,214 64,802 294,493 161,956
License and collaboration revenue        
Revenue:        
Revenue   $ 2,244 $ 6,210 $ 24,908