v3.24.3
Shareholders' Equity (Tables)
 9 Months Ended
Sep. 30, 2024
Stockholders' Equity Note [Abstract]  
Schedule of changes in shareholders' equity (deficit)
Changes in shareholders’ equity for the three and nine months ended September 30, 2024 and September 30, 2023 were as follows:
Common Shares
SharesAmountAdditional Paid-in CapitalAccumulated Deficit
Accumulated Other Comprehensive Loss
Total Shareholders' Equity
Balances as of December 31, 202381,115,723 $887,528 $39,804 $(499,292)$(65)$427,975 
Net loss— — — (179,504)— (179,504)
Issuance of common shares as payment for acquisition of IPR&D asset
242,958 10,347 — — — 10,347 
Issuance of common shares as payment under license and other agreements
97,233 5,637 — — — 5,637 
Issuance of common shares under 2022 Equity Incentive Plan351,307 7,452 (5,296)— — 2,156 
Non-cash share-based compensation expense— — 34,877 — — 34,877 
Other comprehensive loss— — — — (41)(41)
Balances as of March 31, 202481,807,221 910,964 69,385 (678,796)(106)301,447 
Net loss— — — (319,771)— (319,771)
Issuance of common shares, net of offering costs8,544,951 317,720 — — — 317,720 
Issuance of common shares as payment for acquisition of IPR&D asset10,452 446 — — — 446 
Issuance of common shares as payment under license and other agreements1,872,874 65,981 — — — 65,981 
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan110,834 3,442 (1,125)— — 2,317 
Issuance of warrant as payment under license agreement— — 3,340 — — 3,340 
Non-cash share-based compensation expense— — 12,232 — — 12,232 
Other comprehensive income— — — — 28 28 
Balances as of June 30, 202492,346,332 1,298,553 83,832 (998,567)(78)383,740 
Net loss
— — — (160,304)— (160,304)
Issuance of common shares, net of offering costs
2,154,857 76,361 — — — 76,361 
Issuance of common shares as payment for acquisition of IPR&D asset
428 18 — — — 18 
Issuance of common shares under 2022 Equity Incentive Plan
397,422 6,758 (2,954)— — 3,804 
Issuance of common shares as payment under license and other agreements
154 9 — — — 9 
Non-cash share-based compensation expense— — 12,160 — — 12,160 
Other comprehensive income— — — — 218 218 
Balance as of September 30, 2024
94,899,193 $1,381,699 $93,038 $(1,158,871)$140 $316,006 
Common Shares
SharesAmountAdditional Paid-in CapitalAccumulated DeficitAccumulated Other Comprehensive IncomeTotal Shareholders' Equity
Balances as of December 31, 2022
68,190,479 $615,742 $13,869 $(91,124)$284 $538,771 
Net loss— — — (70,492)— (70,492)
Issuance of common shares under 2022 Equity Incentive Plan22,000 504 (172)— — 332 
Non-cash share-based compensation expense
— — 3,765 — — 3,765 
Other comprehensive loss— — — — (118)(118)
Balances as of March 31, 2023
68,212,479 616,246 17,462 (161,616)166 472,258 
Net loss— — — (90,346)— (90,346)
Issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan104,474 1,264 (470)— — 794 
Non-cash share-based compensation expense— — 4,695 — — 4,695 
Other comprehensive loss— — — — (146)(146)
Balance as of June 30, 2023
68,316,953 617,510 21,687 (251,962)20 387,255 
Net loss
— — — (102,574)— (102,574)
Issuance of common shares under 2022 Equity Incentive Plan
47,190 1,251 (520)— — 731 
Non-cash share-based compensation expense
— — 4,456 — — 4,456 
Other comprehensive income
— — — — 138 138 
Balance as of September 30, 2023
68,364,143 $618,761 $25,623 $(354,536)$158 $290,006