Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Clene Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered⁽¹⁾

Proposed Maximum Aggregate Offering Price Per Unit⁽²⁾

Maximum Aggregate Offering Price⁽²⁾

Fee Rate

Amount of Registration Fee

Fees to Be Paid

Equity

Common Stock, par value $0.0001 per share

457(c)

1,146,789

$4.73

$5,424,312

$153.10 per $1,000,000

$830.46

Total Offering Amounts

$5,424,312

$830.46

Total Fees Previously Paid

—

Total Fee Offsets

—

Net Fee Due

$830.46

(1)

Consists of 1,146,789 shares of the Registrant’s common stock, par value $0.0001 per share (“common stock”), issuable to the Selling Shareholders upon conversion of outstanding senior secured convertible promissory notes, and the offer and resale of such shares of common stock by the Selling Shareholders. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), the shares of common stock being registered hereunder include such indeterminate number of shares of common stock as may be issuable with respect to the shares of common stock being registered hereunder as a result of any stock dividends, stock splits, or other similar transactions.