v3.25.0.1
Income Taxes - Additional Information (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Reconciliation Of Income Taxes [Line Items]      
Federal statutory income tax rate 21.00% 21.00% 21.00%
Increase in valuation allowance $ 101,300 $ 127,500 $ 62,400
Valuation allowance changes, description The Company does not expect any significant changes in its valuation allowance positions within the next 12 months.    
Federal net operating loss carryforwards $ 640,000 861,400  
State net operating loss carryforward 723,700 741,000  
International net operating loss carryforwards 900 8,600  
Research and development tax credits, net of UTP $ 181,411 $ 125,424  
Minimum percentage chances of tax benefit to be realized on examination 50.00%    
Expected significant change in unrecognized tax benefits, description The Company does not expect any significant change in its unrecognized tax benefits within the next 12 months.    
Federal [Member]      
Reconciliation Of Income Taxes [Line Items]      
Research and development tax credits, net of UTP $ 155,700    
Research and development tax credit carryforwards, begin to expiration year 2027    
State [Member]      
Reconciliation Of Income Taxes [Line Items]      
Net operating loss carryforwards, begin to expiration year 2027    
Research and development tax credits, net of UTP $ 72,300    
Research and development tax credit carryforwards, begin to expiration year 2026