| Schedule of warrants outstanding and exercisable |
|
Issuance
date |
|
Warrants
outstanding
|
|
|
Exercise
price
per
warrant |
|
|
Warrants
outstanding
and
exercisable
|
|
Contractual
term
|
|
|
|
(number)
|
|
|
|
|
|
(number)
|
|
|
|
December 31, 2015 (1)
|
|
|
681
|
|
|
$
|
52.50
|
|
|
|
681
|
|
See
footnote (1) |
|
December 28, 2016 (2)
|
|
|
272
|
|
|
$
|
52.50
|
|
|
|
272
|
|
See
footnote (1) |
|
April 5, 2019 (3)
|
|
|
58,350
|
|
|
$
|
35.98
|
|
|
|
58,350
|
|
October
7, 2024 |
|
June 12, 2019 (4)
|
|
|
59,523
|
|
|
$
|
42.00
|
|
|
|
59,523
|
|
December
12, 2024 |
|
February 10, 2020 (5)
|
|
|
4,054
|
|
|
$
|
8.75
|
|
|
|
4,054
|
|
February
10, 2025 |
|
February 10, 2020 (6)
|
|
|
15,120
|
|
|
$
|
10.94
|
|
|
|
15,120
|
|
February
10, 2025 |
|
July 6, 2020 (7)
|
|
|
64,099
|
|
|
$
|
12.32
|
|
|
|
64,099
|
|
January
2, 2026 |
|
July 6, 2020 (8)
|
|
|
42,326
|
|
|
$
|
15.95
|
|
|
|
42,326
|
|
January
2, 2026 |
|
December 8, 2020 (9)
|
|
|
83,821
|
|
|
$
|
9.38
|
|
|
|
83,821
|
|
June
8, 2026 |
|
December 8, 2020 (10)
|
|
|
15,543
|
|
|
$
|
12.55
|
|
|
|
15,543
|
|
June
8, 2026 |
|
February 26, 2021 (11)
|
|
|
780,095
|
|
|
$
|
25.20
|
|
|
|
780,095
|
|
August
26, 2026 |
|
February 26, 2021 (12)
|
|
|
93,612
|
|
|
$
|
32.05
|
|
|
|
93,612
|
|
August
26, 2026 |
|
September 29, 2021 (13)
|
|
|
1,143,821
|
|
|
$
|
14.00
|
|
|
|
1,143,821
|
|
March
29, 2027 |
|
September 29, 2021 (14)
|
|
|
137,257
|
|
|
$
|
17.81
|
|
|
|
137,257
|
|
September
27, 2026 |
|
|
|
|
2,498,574
|
|
|
|
|
|
|
|
2,498,574
|
|
|
| |
(1) |
Represents warrants for ordinary shares issuable
upon an exercise price of $52.50
per share, which were granted on December
31, 2015 to Kreos Capital V (Expert) Fund Limited (“Kreos”) in connection with a loan made by Kreos to the
Company and are currently
exercisable (in whole or in part) until the earlier of (i) December 30, 2025 or (ii) immediately prior to the consummation of a merger,
consolidation, or reorganization of the Company with or into, or the sale or license of all or substantially all the assets or shares
of the Company to, any other entity or person, other than a wholly owned subsidiary of the Company, excluding any transaction in which
the Company’s shareholders prior to the transaction will hold more than 50% of the voting and economic rights of the surviving entity
after the transaction. None of these warrants had been exercised as of September 30, 2024. |
| |
(2) |
Represents common warrants that were issued as
part of the $8.0
million drawdown under the Loan Agreement which occurred on December 28, 2016. See footnote 1 for exercisability terms.
|
| |
(3) |
Represents warrants that were issued to certain
institutional purchasers in a private placement in the Company’s registered direct offering of ordinary shares in April 2019.
|
| |
(4) |
Represents warrants
that were issued to certain institutional investors in a warrant exercise agreement in June 2019. |
| |
(5) |
Represents warrants that were issued to certain
institutional purchasers in a private placement in the Company’s best efforts offering of ordinary shares in February 2020. As of
September 30, 2024, 534,300
warrants were exercised for a total consideration of $4,675,125.
During the nine months
ended September 30, 2024, no warrants were exercised. |
| |
(6) |
Represents warrants that were issued to the placement
agent as compensation for its role in the Company’s February 2020 best efforts offering. As of September 30, 2024, 32,880
warrants were exercised for a total consideration of $359,625.
During the nine months
ended September 30, 2024, no warrants were exercised. |
| |
(7) |
Represents warrants that were issued to certain
institutional purchasers in a private placement in our registered direct offering of ordinary shares in July 2020. As of September 30,
2024, 288,634
warrants were exercised for a total consideration of $3,556,976.
During the nine months
that ended September 30, 2024, no warrants were exercised. |
| |
(8) |
Represents warrants
that were issued to the placement agent as compensation for his role in the Company’s July 2020 registered direct offering.
|
| |
(9) |
Represents warrants that were issued to certain
institutional purchasers in a private placement in our private placement offering of ordinary shares in December 2020. As of September
30, 2024, 514,010
warrants were exercised for a total consideration of $4,821,416.
During the nine months
that ended September 30, 2024, no warrants were exercised. |
| |
(10) |
Represents warrants that were issued to the placement
agent as compensation for its role in the Company’s December 2020 private placement. As of September 30, 2024, 32,283
warrants were exercised for a total consideration of $405,003.
During the nine months
that ended September 30, 2024, no warrants were exercised. |
| |
(11) |
Represents warrants
that were issued to certain institutional purchasers in a private placement in our private placement offering of ordinary shares in February
2021. |
| |
(12) |
Represents warrants
that were issued to the placement agent as compensation for its role in the Company’s February 2021 private placement.
|
| |
(13) |
Represents warrants
that were issued to certain institutional purchasers in a private placement in our registered direct offering of ordinary shares in September
2021. |
| |
(14) |
Represents warrants
that were issued to the placement agent as compensation for its role in the Company’s September 2021 registered direct offering.
|
|
|
Issuance
date |
|
Warrants
outstanding
|
|
|
Exercise
price
per
warrant |
|
|
Warrants
outstanding
and
exercisable
|
|
Contractual
term
|
|
|
|
(number)
|
|
|
|
|
|
(number)
|
|
|
|
December 31, 2015 (1)
|
|
|
4,771
|
|
|
$
|
7.500
|
|
|
|
4,771
|
|
See
footnote (1) |
|
December 28, 2016 (2)
|
|
|
1,908
|
|
|
$
|
7.500
|
|
|
|
1,908
|
|
See
footnote (1) |
|
February 25, 2019 (5)
|
|
|
45,600
|
|
|
$
|
7.187
|
|
|
|
45,600
|
|
February
21, 2024 |
|
April 5, 2019 (6)
|
|
|
408,457
|
|
|
$
|
5.140
|
|
|
|
408,457
|
|
October
7, 2024 |
|
April 5, 2019 (7)
|
|
|
49,015
|
|
|
$
|
6.503
|
|
|
|
49,015
|
|
April
3, 2024 |
|
June 5, 2019, and June
6, 2019 (8) |
|
|
1,464,665
|
|
|
$
|
7.500
|
|
|
|
1,464,665
|
|
June
5, 2024 |
|
June 5, 2019 (9)
|
|
|
87,880
|
|
|
$
|
9.375
|
|
|
|
87,880
|
|
June
5, 2024 |
|
June 12, 2019 (10)
|
|
|
416,667
|
|
|
$
|
6.000
|
|
|
|
416,667
|
|
December
12, 2024 |
|
June 10, 2019 (11)
|
|
|
50,000
|
|
|
$
|
7.500
|
|
|
|
50,000
|
|
June
10, 2024 |
|
February 10, 2020 (12)
|
|
|
28,400
|
|
|
$
|
1.250
|
|
|
|
28,400
|
|
February
10, 2025 |
|
February 10, 2020 (13)
|
|
|
105,840
|
|
|
$
|
1.563
|
|
|
|
105,840
|
|
February
10, 2025 |
|
July 6, 2020 (14)
|
|
|
448,698
|
|
|
$
|
1.760
|
|
|
|
448,698
|
|
January
2, 2026 |
|
July 6, 2020 (15)
|
|
|
296,297
|
|
|
$
|
2.278
|
|
|
|
296,297
|
|
January
2, 2026 |
|
December 8, 2020 (16)
|
|
|
586,760
|
|
|
$
|
1.340
|
|
|
|
586,760
|
|
June
8, 2026 |
|
December 8, 2020 (17)
|
|
|
108,806
|
|
|
$
|
1.792
|
|
|
|
108,806
|
|
June
8, 2026 |
|
February 26, 2021 (18)
|
|
|
5,460,751
|
|
|
$
|
3.600
|
|
|
|
5,460,751
|
|
August
26, 2026 |
|
February 26, 2021 (19)
|
|
|
655,290
|
|
|
$
|
4.578
|
|
|
|
655,290
|
|
August
26, 2026 |
|
September 29, 2021 (20)
|
|
|
8,006,759
|
|
|
$
|
2.000
|
|
|
|
8,006,759
|
|
March
29, 2027 |
|
September 29, 2021 (21)
|
|
|
960,811
|
|
|
$
|
2.544
|
|
|
|
960,811
|
|
September
27, 2026 |
|
|
|
|
19,187,375
|
|
|
|
|
|
|
|
19,187,375
|
|
|
|