| Schedule of Segment Reporting Information, by Segment |
total revenue from customers by geographic region. | | | | | | | | | | | | | | | | | | | | | | | Year Ended December 31, | | (In thousands) | | 2024 | | 2023 | | 2022 | Revenue: | | | | | | | | United States | | $ | 2,569,775 | | | $ | 2,346,489 | | | $ | 1,966,541 | | | Outside of United States | | 189,092 | | | 153,277 | | | 117,738 | | | Total revenues (1) | | 2,758,867 | | | 2,499,766 | | | 2,084,279 | | | Less: | | | | | | | | Cost of sales: | | | | | | | | Production costs | | 467,347 | | | 393,367 | | | 329,492 | | | Personnel expenses | | 197,338 | | | 182,015 | | | 160,136 | | | Intangible asset amortization | | 84,068 | | | 83,316 | | | 86,967 | | | Facility and support services (2) | | 68,535 | | | 54,417 | | | 63,608 | | | Stock-based compensation | | 20,518 | | | 20,761 | | | 19,218 | | Other cost of sales | | 2,344 | | | 3,688 | | | 1,940 | | | Research and development expenses: | | | | | | | | Personnel expenses | | 182,190 | | | 180,281 | | | 143,259 | | | Direct research and development costs | | 110,054 | | | 129,691 | | | 158,731 | | | Facility and support services (2) | | 56,184 | | | 64,088 | | | 45,512 | | | Stock-based compensation | | 39,684 | | | 41,242 | | | 33,825 | | Other research and development (3) | | 28,900 | | | 3,371 | | | 8,179 | | | Professional & legal | | 10,906 | | | 7,209 | | | 3,912 | | | Intangible asset amortization | | 3,292 | | | 1,045 | | | 773 | | | Sales and marketing expenses: | | | | | | | | Personnel expenses | | 500,286 | | | 471,613 | | | 494,116 | | | Direct marketing costs | | 212,838 | | | 183,720 | | | 238,111 | | | Professional & legal | | 70,399 | | | 49,739 | | | 54,698 | | | Stock-based compensation | | 68,236 | | | 73,016 | | | 69,267 | | Other sales and marketing (3) | | 19,287 | | | 24,348 | | | 13,432 | | | Facility and support services (2) | | 15,385 | | | 17,675 | | | 50,419 | | | Intangible asset amortization | | 7,694 | | | 7,694 | | | 9,601 | | | General and administrative expenses: | | | | | | | | Personnel expenses | | 346,432 | | | 336,865 | | | 341,595 | | | Facility and support services (2) | | 184,984 | | | 181,425 | | | 134,954 | | | Professional & legal | | 125,608 | | | 166,760 | | | 110,039 | | | Stock-based compensation | | 86,447 | | | 96,293 | | | 84,513 | | Other general and administrative (3) | | 38,250 | | | 18,841 | | | (7,827) | | | Intangible asset amortization | | 104 | | | 104 | | | 107 | | | Other: | | | | | | | | Impairment of long-lived and indefinite-lived assets | | 869,460 | | | 621 | | | 15,969 | | Other segment items (4) | | (21,742) | | | (91,693) | | | 52,303 | | | Income tax expense (benefit) | | (7,304) | | | 2,403 | | | (9,064) | | | Segment and consolidated net loss | | $ | (1,028,857) | | | $ | (204,149) | | | $ | (623,506) | |
_______________________________ (1) Product revenues are attributed to countries based on ship-to location. Refer to Note 2 for the Company’s disaggregated revenue disclosures. (2) Facilities and support services is inclusive of depreciation expense. Refer to the consolidated statements of cash flows for presentation of total depreciation expense. (3) Other research and development primarily includes a $25.8 million for a license agreement termination for the year ended December 31, 2024. Other sales and marketing primarily includes miscellaneous customer-oriented support activities. Other general and administrative primarily includes changes in fair value to outstanding contingent consideration liabilities, foreign currency gains and losses, corporate liability insurance, and other miscellaneous charges. (4) Inclusive of other operating income (loss), investment income (loss), net, and interest expense as presented in the consolidated statement of operations.
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