v3.25.0.1
Income Taxes (Tables)
12 Months Ended
Dec. 31, 2024
Income Tax Disclosure [Abstract]  
ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock

A reconciliation of the federal statutory income tax rate and the Company’s effective income tax rate is as follows:

 

 

Year Ended December 31,

 

 

2024

 

2023

 

2022

Federal statutory income tax rate

 

(21.0)%

 

(21.0)%

 

(21.0)%

State income taxes

 

(7.9)

 

(8.6)

 

(8.3)

Research and development tax credits

 

(7.4)

 

(6.9)

 

(5.3)

Stock-based compensation

 

2.0

 

1.6

 

(0.1)

Non-deductible officers' compensation

 

0.1

 

-

 

0.1

In-process research and development

 

-

 

-

 

2.5

Change in valuation allowance

 

34.2

34.9

32.1

Effective income tax rate

 

—%

 

—%

 

—%

Summary of Company's Net Deferred Tax Assets (Liabilities)

The Company’s net deferred tax assets (liabilities) consisted of the following:

 

 

December 31,

 

 

 

2024

 

 

2023

 

 

 

(in thousands)

 

Deferred tax assets:

 

 

 

 

 

 

Net operating loss carryforwards

 

$

296,766

 

 

$

258,664

 

Research and development credit carryforwards

 

 

200,816

 

 

 

151,333

 

Section 174 capitalized research

 

 

216,469

 

 

 

150,993

 

Operating lease liability

 

 

57,438

 

 

 

31,183

 

Deferred revenue

 

 

10,634

 

 

 

9,633

 

Stock-based compensation

 

 

34,827

 

 

 

30,408

 

Accruals and allowances

 

 

5,468

 

 

 

6,244

 

Prepaid rent

 

 

4,410

 

 

 

1,190

 

Equity investment adjustments

 

 

16,560

 

 

 

7,580

 

Intangibles, including in-process research and development

 

 

920

 

 

 

1,017

 

Capitalized start-up costs

 

 

211

 

 

 

249

 

Gross deferred tax assets

 

 

844,519

 

 

 

648,494

 

Deferred tax asset valuation allowance

 

 

(783,211

)

 

 

(616,082

)

Total deferred tax assets

 

 

61,308

 

 

 

32,412

 

Deferred tax liabilities:

 

 

 

 

 

 

Fixed assets

 

 

(1,385

)

 

 

(1,221

)

Operating lease right-of-use assets

 

 

(59,923

)

 

 

(31,191

)

Total deferred tax liabilities

 

 

(61,308

)

 

 

(32,412

)

Net deferred tax asset (liability)

 

$

-

 

 

$

-