Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands |
Dec. 31, 2024 |
Dec. 31, 2023 |
|---|---|---|
| Deferred tax assets: | ||
| Intangible assets | $ 177,244 | $ 160,281 |
| Research and development capitalization | 21,474 | 32,163 |
| Share-based compensation | 38,494 | 31,712 |
| Net operating loss carryforwards | 312,672 | 329,135 |
| Research and development credits | 81,340 | 67,667 |
| Orphan drug credits | 48,015 | 34,023 |
| Development derivative liability | 75,190 | |
| Convertible debt | 1,021 | 5,582 |
| Fixed Assets | 194 | 18 |
| Lease liability | 3,026 | 2,888 |
| Accruals | 7,668 | 9,998 |
| Deferred Interest Expense | 1,974 | |
| Inventory Reserves | 31,476 | 6,317 |
| UNICAP | 1,806 | 1,086 |
| Total deferred tax assets | 726,404 | 756,060 |
| Deferred tax liabilities: | ||
| Right-of-use asset | (2,821) | (2,672) |
| Total deferred tax liabilities | (2,821) | (2,672) |
| Net deferred tax assets before allowance: | 723,583 | 753,388 |
| Less valuation allowance | $ (723,583) | $ (753,388) |
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- Definition Deferred tax asset lease liability. No definition available.
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- Definition Deferred tax assets convertible debt. No definition available.
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- Definition Deferred tax assets deferred interest expense. No definition available.
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- Definition Deferred tax assets orphan drug credits. No definition available.
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- Definition Deferred tax assets, research and development capitalization. No definition available.
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- Definition Deferred tax assets, Uniform Capitalization (UNICAP). No definition available.
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- Definition Deferred tax liability right of use asset. No definition available.
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- Definition Net deferred tax assets before valuation allowance. No definition available.
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- Definition Amount of deferred tax liability attributable to taxable temporary differences. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from derivative instruments. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from inventory. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from property, plant, and equipment. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from reserves and accruals. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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