Property and equipment consist of the following (in thousands):


	December 31,
	2024			2023
Furniture and fixtures	$	508		$	1,309
Computer and office equipment		2,444			3,132
Software		1,188			2,130
Leasehold improvements—building		59,485			59,038
Scientific equipment		35,895			78,853
Total property and equipment, gross		99,520			144,462
Less accumulated depreciation and amortization		(35,136	)		(47,626	)
Total property and equipment, net	$	64,384		$	96,836

The Company recognized an impairment charge of $13.4 million of long-lived asset impairment described in Note 1 above for the year ended December 31, 2024, which was calculated as the difference between the fair value of the assets and its carrying value. The cost basis for these assets was updated to fair value. The fair value was based on a cost approach which utilized Level 3 non-recurring fair value inputs and assumptions.

Depreciation expense related to property and equipment was $19.0 million and $18.3 million, for the years ended December 31, 2024 and 2023, respectively.