Income taxes.

No definition available.

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- Definition

Maximum percentage of likelihood of uncertain tax position recognized to be sustained.

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No definition available.

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- Definition

Net operating loss and research and development credit carryforwards limitations on cumulative change in ownership minimum percentage.

+ References

No definition available.

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- Definition

Net operating loss and research and development credit carryforwards limitations on cumulative change in ownership period.

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No definition available.

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- Definition

Operating loss carryforwards expiration year.

+ References

No definition available.

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- Definition

Tax credit carryforward expiration year.

+ References

No definition available.

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- Definition

Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 2
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-2

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- Definition

Amount of operating loss carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
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-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-3

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- Definition

The amount of the tax credit carryforward, before tax effects, available to reduce future taxable income under enacted tax laws.

+ References

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- Definition

Amount of expense for interest on an underpayment of income taxes and penalties related to a tax position claimed or expected to be claimed in the tax return.

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Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 740
-SubTopic 10
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- Definition

The total amount of unrecognized tax benefits that, if recognized, would affect the effective tax rate.

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- Definition

Amount of increase (decrease) in the valuation allowance for a specified deferred tax asset.

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Income Taxes (Details Textual) - USD ($)	12 Months Ended
Income Taxes (Details Textual) - USD ($)	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2018
Income Taxes [Line Items]
Valuation allowance	$ 138,044,000	$ 108,806,000
Valuation allowance change	$ 29,200,000	10,200,000
Maximum percentage of likelihood of uncertain tax position recognized to be sustained	50.00%
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense	$ 0	$ 0	$ 0
Unrecognized tax benefits impacting effective tax rate	$ 0
Net Operating Loss and Research and Development Credit Carryforwards Limitations On Cumulative Change In Ownership Minimum Percentage	50.00%
Net Operating Loss and Research and Development Credit Carryforwards Limitations on Cumulative Change In Ownership Period	3 years
Orphan Drug Credit [Member]
Income Taxes [Line Items]
Credit Carryforward Amount	$ 4,700,000
Credit Carryforward Expiration Year	2042
Federal [Member]
Income Taxes [Line Items]
Operating Loss Carryforwards	$ 47,500,000
Federal [Member] \| Research Tax Credit Carryforward [Member]
Income Taxes [Line Items]
Credit Carryforward Amount	$ 19,800,000
Credit Carryforward Expiration Year	2037
State [Member]
Income Taxes [Line Items]
Operating Loss Carryforwards	$ 223,500,000			$ 400,000
Operating Loss Carryforwards Expiration Year	2039
Credit Carryforward Amount	$ 800,000
Credit Carryforward Expiration Year	2037
State [Member] \| Research Tax Credit Carryforward [Member]
Income Taxes [Line Items]
Credit Carryforward Amount	$ 11,500,000