12. Stock-Based Compensation

In January 2025, the number of shares of common stock available for issuance under the Company’s 2015 Omnibus Incentive Plan, or the 2015 Plan, was increased by 3,427,778 shares of common stock due to the automatic annual provision to increase shares of common stock available under the 2015 Plan. Additionally in July 2024 and in December 2024, the Company’s board of directors approved increases of 500,000 shares and 1,200,000 shares, respectively, of common stock available for issuance under the Company’s 2023 Inducement Plan, or the Inducement Plan.

As of June 30, 2025, there were 4,781,319 shares of common stock available for issuance under the 2015 Plan and 966,200 shares of common stock available for issuance under the Inducement Plan.

In addition, stock-based compensation expense of $0.2 million was capitalized to inventory as of June 30, 2025, which represents the stock-based compensation expense incurred related to employees involved in the manufacturing process of finished goods and samples.

As of June 30, 2025, there were $92.2 million of unrecognized compensation costs related to employee and non-employee unvested stock options and RSUs granted under the Inducement Plan, 2015 Plan and the Company’s 2007 Stock Plan, which are expected to be recognized over a weighted-average remaining service period of 2.57 years.

Employee Benefit Plan

The Company maintains a defined contribution 401(k) retirement plan. For the three and six months ended June 30, 2025, the Company made $0.3 million and $2.6 million of contributions to the plan, respectively. For the three and six months ended June 30, 2024, the Company made $0.6 million and $2.1 million of contributions to the plan, respectively. The Company’s contributions are made in cash.