CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS’ EQUITY - USD ($)
$ in Thousands |
Total |
At-The-Market Offering Program |
Ordinary shares |
Ordinary shares
At-The-Market Offering Program
|
Preferred shares |
Additional paid-in capital |
Additional paid-in capital
At-The-Market Offering Program
|
Accumulated deficit |
Accumulated other comprehensive loss |
| Beginning balance (in shares) at Dec. 31, 2023 |
|
|
89,825,000
|
|
|
|
|
|
|
| Beginning balance (in shares) at Dec. 31, 2023 |
|
|
|
|
5,194,000
|
|
|
|
|
| Beginning balance at Dec. 31, 2023 |
$ 87,739
|
|
$ 898
|
|
$ 52
|
$ 855,452
|
|
$ (745,496)
|
$ (23,167)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
(27,342)
|
|
|
|
|
|
|
(27,342)
|
|
| Other comprehensive income (loss) |
(589)
|
|
|
|
|
|
|
|
(589)
|
| Issuance of common stock, net of issuance costs (in shares) |
|
|
|
640,000
|
|
|
|
|
|
| Issuance of common stock, net of issuance costs |
|
$ 9,250
|
|
$ 6
|
|
|
$ 9,244
|
|
|
| Amortization of deferred issuance costs |
(3)
|
|
|
|
|
(3)
|
|
|
|
| Conversion of preferred stock into ordinary shares (in shares) |
|
|
5,194,000
|
|
(5,194,000)
|
|
|
|
|
| Conversion of preferred stock into ordinary shares |
0
|
|
$ 52
|
|
$ (52)
|
|
|
|
|
| Exercise of stock options (in shares) |
|
|
390,000
|
|
|
|
|
|
|
| Exercise of stock options |
3,356
|
|
$ 3
|
|
|
3,353
|
|
|
|
| Employee share purchase plan share issuance (in shares) |
|
|
48,000
|
|
|
|
|
|
|
| Employee share purchase plan share issuance |
584
|
|
$ 1
|
|
|
583
|
|
|
|
| Share-based compensation expense |
5,389
|
|
|
|
|
5,389
|
|
|
|
| Ending balance (in shares) at Mar. 31, 2024 |
|
|
96,097,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Mar. 31, 2024 |
|
|
|
|
0
|
|
|
|
|
| Ending balance at Mar. 31, 2024 |
78,384
|
|
$ 960
|
|
$ 0
|
874,018
|
|
(772,838)
|
(23,756)
|
| Beginning balance (in shares) at Dec. 31, 2023 |
|
|
89,825,000
|
|
|
|
|
|
|
| Beginning balance (in shares) at Dec. 31, 2023 |
|
|
|
|
5,194,000
|
|
|
|
|
| Beginning balance at Dec. 31, 2023 |
87,739
|
|
$ 898
|
|
$ 52
|
855,452
|
|
(745,496)
|
(23,167)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
(43,789)
|
|
|
|
|
|
|
|
|
| Other comprehensive income (loss) |
(635)
|
|
|
|
|
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2024 |
|
|
96,338,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2024 |
|
|
|
|
0
|
|
|
|
|
| Ending balance at Sep. 30, 2024 |
74,663
|
|
$ 963
|
|
$ 0
|
886,787
|
|
(789,285)
|
(23,802)
|
| Beginning balance (in shares) at Mar. 31, 2024 |
|
|
96,097,000
|
|
|
|
|
|
|
| Beginning balance (in shares) at Mar. 31, 2024 |
|
|
|
|
0
|
|
|
|
|
| Beginning balance at Mar. 31, 2024 |
78,384
|
|
$ 960
|
|
$ 0
|
874,018
|
|
(772,838)
|
(23,756)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
(13,822)
|
|
|
|
|
|
|
(13,822)
|
|
| Other comprehensive income (loss) |
(459)
|
|
|
|
|
|
|
|
(459)
|
| Exercise of stock options (in shares) |
|
|
107,000
|
|
|
|
|
|
|
| Exercise of stock options |
723
|
|
$ 1
|
|
|
722
|
|
|
|
| Share-based compensation expense |
5,462
|
|
|
|
|
5,462
|
|
|
|
| Ending balance (in shares) at Jun. 30, 2024 |
|
|
96,204,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Jun. 30, 2024 |
|
|
|
|
0
|
|
|
|
|
| Ending balance at Jun. 30, 2024 |
70,288
|
|
$ 961
|
|
$ 0
|
880,202
|
|
(786,660)
|
(24,215)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
(2,625)
|
|
|
|
|
|
|
(2,625)
|
|
| Other comprehensive income (loss) |
413
|
|
|
|
|
|
|
|
413
|
| Exercise of stock options (in shares) |
|
|
69,000
|
|
|
|
|
|
|
| Exercise of stock options |
400
|
|
$ 1
|
|
|
399
|
|
|
|
| Employee share purchase plan share issuance (in shares) |
|
|
65,000
|
|
|
|
|
|
|
| Employee share purchase plan share issuance |
777
|
|
$ 1
|
|
|
776
|
|
|
|
| Share-based compensation expense |
5,410
|
|
|
|
|
5,410
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2024 |
|
|
96,338,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2024 |
|
|
|
|
0
|
|
|
|
|
| Ending balance at Sep. 30, 2024 |
$ 74,663
|
|
$ 963
|
|
$ 0
|
886,787
|
|
(789,285)
|
(23,802)
|
| Beginning balance (in shares) at Dec. 31, 2024 |
96,518,000
|
|
96,518,000
|
|
|
|
|
|
|
| Beginning balance (in shares) at Dec. 31, 2024 |
0
|
|
|
|
0
|
|
|
|
|
| Beginning balance at Dec. 31, 2024 |
$ 73,848
|
|
$ 965
|
|
$ 0
|
891,791
|
|
(794,328)
|
(24,580)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
(4,920)
|
|
|
|
|
|
|
(4,920)
|
|
| Other comprehensive income (loss) |
268
|
|
|
|
|
|
|
|
268
|
| Exercise of stock options (in shares) |
|
|
60,000
|
|
|
|
|
|
|
| Exercise of stock options |
282
|
|
$ 1
|
|
|
281
|
|
|
|
| Vesting of restricted shares (in shares) |
|
|
8,000
|
|
|
|
|
|
|
| Employee share purchase plan share issuance (in shares) |
|
|
46,000
|
|
|
|
|
|
|
| Employee share purchase plan share issuance |
409
|
|
|
|
|
408
|
|
1
|
|
| Share-based compensation expense |
4,183
|
|
|
|
|
4,183
|
|
|
|
| Ending balance (in shares) at Mar. 31, 2025 |
|
|
96,632,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Mar. 31, 2025 |
|
|
|
|
0
|
|
|
|
|
| Ending balance at Mar. 31, 2025 |
$ 74,070
|
|
$ 966
|
|
$ 0
|
896,663
|
|
(799,247)
|
(24,312)
|
| Beginning balance (in shares) at Dec. 31, 2024 |
96,518,000
|
|
96,518,000
|
|
|
|
|
|
|
| Beginning balance (in shares) at Dec. 31, 2024 |
0
|
|
|
|
0
|
|
|
|
|
| Beginning balance at Dec. 31, 2024 |
$ 73,848
|
|
$ 965
|
|
$ 0
|
891,791
|
|
(794,328)
|
(24,580)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
4,765
|
|
|
|
|
|
|
|
|
| Other comprehensive income (loss) |
$ 1,004
|
|
|
|
|
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2025 |
97,235,000
|
|
97,235,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2025 |
0
|
|
|
|
0
|
|
|
|
|
| Ending balance at Sep. 30, 2025 |
$ 98,225
|
|
$ 972
|
|
$ 0
|
910,391
|
|
(789,562)
|
(23,576)
|
| Beginning balance (in shares) at Mar. 31, 2025 |
|
|
96,632,000
|
|
|
|
|
|
|
| Beginning balance (in shares) at Mar. 31, 2025 |
|
|
|
|
0
|
|
|
|
|
| Beginning balance at Mar. 31, 2025 |
74,070
|
|
$ 966
|
|
$ 0
|
896,663
|
|
(799,247)
|
(24,312)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
9,665
|
|
|
|
|
|
|
9,665
|
|
| Other comprehensive income (loss) |
666
|
|
|
|
|
|
|
|
666
|
| Exercise of stock options (in shares) |
|
|
145,000
|
|
|
|
|
|
|
| Exercise of stock options |
981
|
|
$ 1
|
|
|
980
|
|
|
|
| Share-based compensation expense |
5,327
|
|
|
|
|
5,327
|
|
|
|
| Ending balance (in shares) at Jun. 30, 2025 |
|
|
96,777,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Jun. 30, 2025 |
|
|
|
|
0
|
|
|
|
|
| Ending balance at Jun. 30, 2025 |
90,709
|
|
$ 967
|
|
$ 0
|
902,970
|
|
(789,582)
|
(23,646)
|
| Increase (Decrease) in Stockholders' Equity [Roll Forward] |
|
|
|
|
|
|
|
|
|
| Net income (loss) |
20
|
|
|
|
|
|
|
20
|
|
| Other comprehensive income (loss) |
70
|
|
|
|
|
|
|
|
70
|
| Exercise of stock options (in shares) |
|
|
313,000
|
|
|
|
|
|
|
| Exercise of stock options |
1,957
|
|
$ 3
|
|
|
1,954
|
|
|
|
| Vesting of restricted shares (in shares) |
|
|
72,000
|
|
|
|
|
|
|
| Vesting of restricted shares |
0
|
|
$ 1
|
|
|
(1)
|
|
|
|
| Employee share purchase plan share issuance (in shares) |
|
|
73,000
|
|
|
|
|
|
|
| Employee share purchase plan share issuance |
550
|
|
$ 1
|
|
|
549
|
|
|
|
| Share-based compensation expense |
$ 4,919
|
|
|
|
|
4,919
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2025 |
97,235,000
|
|
97,235,000
|
|
|
|
|
|
|
| Ending balance (in shares) at Sep. 30, 2025 |
0
|
|
|
|
0
|
|
|
|
|
| Ending balance at Sep. 30, 2025 |
$ 98,225
|
|
$ 972
|
|
$ 0
|
$ 910,391
|
|
$ (789,562)
|
$ (23,576)
|