v3.25.3
Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Income Statement [Abstract]        
License and other revenue $ 0 $ 0 $ 15,000 $ 0
Operating expenses:        
Research and development 41,563 33,903 117,747 89,370
General and administrative 12,227 12,502 36,473 37,105
Loss from operations (53,790) (46,405) (139,220) (126,475)
Interest and investment income 3,765 3,340 16,035 9,171
Interest expense (2,890) (2,557) (8,651) (7,611)
Other non-operating income (expense), net (1,810) 3,664 2,808 2,281
Loss before income taxes (54,725) (41,958) (129,028) (122,634)
Income tax expense 166 608 2,341 1,794
Net loss (54,891) (42,566) (131,369) (124,428)
Other comprehensive (loss) income:        
Foreign currency translation adjustment 691 (412) 855 (498)
Unrealized (loss) gain on available for sale marketable securities, net of reclassification adjustment and tax 318 912 (2,468) 1,100
Other comprehensive (loss) income 1,009 500 (1,613) 602
Total comprehensive loss $ (53,882) $ (42,066) $ (132,982) $ (123,826)
Net loss per ordinary share - basic (in dollars per share) $ (0.41) $ (0.37) $ (0.98) $ (1.15)
Net loss per ordinary share - diluted (in dollars per share) $ (0.41) $ (0.37) $ (0.98) $ (1.15)
Weighted average ordinary shares outstanding - basic (in shares) 134,163,492 116,253,902 133,627,043 108,571,742
Weighted average ordinary shares outstanding - diluted (in shares) 134,163,492 116,253,902 133,627,043 108,571,742