The amount of net proceeds from issuance of royalty financing agreement.

No definition available.

Name:	qure_NetProceedsFromIssuanceOfRoyaltyFinancingAgreement
Namespace Prefix:	qure_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The amount of interest expense net of interest paid on royalty financing agreement.

+ References

No definition available.

+ Details

Name:	qure_RoyaltyFinancingAgreementInterestExpense
Namespace Prefix:	qure_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The amount of maximum rights to all other royalties, as well as contractual milestones retained by the company.

+ References

No definition available.

+ Details

Name:	qure_RoyaltyFinancingAgreementMaximumRightToAllOtherRoyaltiesAndContractualMilestonesRetained
Namespace Prefix:	qure_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Ratio of upfront payment the purchaser will receive under the royalty financing agreement.

+ References

No definition available.

+ Details

Name:	qure_RoyaltyFinancingAgreementRatioOfUpfrontPaymentPurchaserIsEntitledToReceive
Namespace Prefix:	qure_
Data Type:	xbrli:pureItemType
Balance Type:	na
Period Type:	instant

- Definition

The amount of upfront payment payable to purchaser under the royalty financing agreement.

+ References

No definition available.

+ Details

Name:	qure_RoyaltyFinancingAgreementUpfrontPaymentPayableToPurchaser
Namespace Prefix:	qure_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The amount of upfront payment received under the royalty financing agreement.

+ References

No definition available.

+ Details

Name:	qure_RoyaltyFinancingAgreementUpfrontPaymentReceived
Namespace Prefix:	qure_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 808
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479402/808-10-50-1

+ Details

Name:	us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Effective interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 835
-SubTopic 30
-Name Accounting Standards Codification
-Section 55
-Paragraph 8
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482949/835-30-55-8

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 210
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(22)(a)(1))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 835
-SubTopic 30
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482900/835-30-50-1

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Topic 835
-SubTopic 30
-Name Accounting Standards Codification
-Section 45
-Paragraph 2
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482925/835-30-45-2

Reference 5: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 6
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481139/470-20-50-6

+ Details

Name:	us-gaap_DebtInstrumentInterestRateEffectivePercentage
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

- Details

Name:	srt_RangeAxis=srt_MinimumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_RangeAxis=srt_MaximumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_CounterpartyNameAxis=qure_CslBehringCollaborationMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_TypeOfArrangementAxis=us-gaap_RoyaltyAgreementsMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_StatementScenarioAxis=qure_FirstHardCapDateMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_StatementScenarioAxis=qure_IfPaidThroughDecember312038Member
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_StatementScenarioAxis=qure_If2024NetSalesDoNotExceedPreSpecifiedThresholdMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

Royalty Financing Agreement (Details) $ in Thousands		1 Months Ended	9 Months Ended
Royalty Financing Agreement (Details) $ in Thousands	Jun. 05, 2023 USD ($)	May 31, 2023 USD ($)	Sep. 30, 2025 USD ($)	Sep. 30, 2024 USD ($)
CSL Behring collaboration
Royalty financing agreement interest expense, net of interest paid			$ 29,209	$ 33,107
Minimum
CSL Behring collaboration
Effective interest rate (as a percent)				12.00%
Maximum
CSL Behring collaboration
Effective interest rate (as a percent)				13.50%
CSL Behring
CSL Behring collaboration
Maximum rights to all other royalties, as well as contractual milestones retained			1,300,000
Royalty Financing Agreement
CSL Behring collaboration
Upfront payment received		$ 375,000
Upfront payment payable to purchaser			843,800
Net proceeds from the Royalty Financing Agreement	$ 370,100		370,100
Royalty financing agreement interest expense, net of interest paid			$ 40,884
Royalty Financing Agreement \| Minimum
CSL Behring collaboration
Effective interest rate (as a percent)			10.50%	12.00%
Royalty Financing Agreement \| Maximum
CSL Behring collaboration
Effective interest rate (as a percent)			12.00%	13.50%
Royalty Financing Agreement \| First Hard Cap Date
CSL Behring collaboration
Upfront payment payable to purchaser		$ 693,800
Ratio of upfront payment		1.85
Royalty financing agreement interest expense, net of interest paid			$ 473,700
Royalty Financing Agreement \| If paid through December 31, 2038
CSL Behring collaboration
Ratio of upfront payment		2.25
Royalty Financing Agreement \| If 2024 net sales do not exceed a pre-specified threshold
CSL Behring collaboration
Upfront payment payable to purchaser		$ 25,000