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Share-based compensation - Summary of share-based compensation expense and unrecognized costs (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended
	Jun. 30, 2025	Jun. 30, 2018	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
2014 Plan
Share-based compensation
Share-based compensation expense			$ 3,522	$ 3,438	$ 13,016	$ 17,509
Unrecognized compensation costs			$ 34,288		$ 34,288
Weighted-average remaining period for recognition (in years)					2 years 4 months 17 days
Increase in authorized shares	2,400,000
Ordinary shares available for issue			4,414,685		4,414,685
2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			$ 3,522	3,438	$ 13,016	17,509
Cost of contract manufacturing revenues \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense						1,035
Research and development expenses \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			695	1,413	5,916	7,694
Selling, general and administrative expenses \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			2,827	2,025	7,100	8,780
Share options \| 2014 Plan
Share-based compensation
Unrecognized compensation costs			13,621		$ 13,621
Weighted-average remaining period for recognition (in years)					2 years 7 months 17 days
Share options \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			1,829	2,003	$ 5,128	7,576
Restricted Share Units \| 2014 Plan
Share-based compensation
Unrecognized compensation costs			20,501		$ 20,501
Weighted-average remaining period for recognition (in years)					2 years 2 months 23 days
Restricted Share Units \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			2,837	1,615	$ 7,597	10,199
Performance Share Units \| 2014 Plan
Share-based compensation
Unrecognized compensation costs			166		$ 166
Weighted-average remaining period for recognition (in years)					3 months
Performance Share Units \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			$ (1,159)	$ (180)	$ 276	$ (276)
ESPP \| Employee Share Purchase Plan
Share-based compensation
Ordinary shares available for issue		150,000	86,712	86,712	86,712	86,712
Discounted rate for purchase of shares		85.00%
ESPP \| 2014 Plans and ESPP
Share-based compensation
Share-based compensation expense			$ 15		$ 15	$ 10