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  <xs:element name="MilestonePayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="esla_MilestonePayment"/>
  <xs:element name="RemittedAmountofBusinessCombination" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_RemittedAmountofBusinessCombination"/>
  <xs:element name="AdditionalCostPayableToMutualAgreement" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_AdditionalCostPayableToMutualAgreement"/>
  <xs:element name="InterestCharges" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_InterestCharges"/>
  <xs:element name="AdditionalInvoicePerPatient" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_AdditionalInvoicePerPatient"/>
  <xs:element name="MileStoneFees" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_MileStoneFees"/>
  <xs:element name="ExchangePreferredShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="esla_ExchangePreferredShares"/>
  <xs:element name="LeasesAndRentExpense" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_LeasesAndRentExpense"/>
  <xs:element name="ServiceAgreementCost" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="esla_ServiceAgreementCost"/>
  <xs:element name="PreferredStockDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_PreferredStockDetailsTable"/>
  <xs:element name="SharesBasedOnAnExchangeRatio" type="xbrli:decimalItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_SharesBasedOnAnExchangeRatio"/>
  <xs:element name="StockholdersEquityDeficitDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_StockholdersEquityDeficitDetailsTable"/>
  <xs:element name="ReceivedCommonSharesOfInvestor" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ReceivedCommonSharesOfInvestor"/>
  <xs:element name="ThresholdTradingDaysForCommonStock" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ThresholdTradingDaysForCommonStock"/>
  <xs:element name="GrossProceeds" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_GrossProceeds"/>
  <xs:element name="TrueUpPricePerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_TrueUpPricePerShare"/>
  <xs:element name="ContractualFloorPricePerShare" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ContractualFloorPricePerShare"/>
  <xs:element name="PurchaseofWarrantsShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_PurchaseofWarrantsShares"/>
  <xs:element name="PeriodToFileRegistrationStatementAfterInitialBusinessCombination" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_PeriodToFileRegistrationStatementAfterInitialBusinessCombination"/>
  <xs:element name="PeriodForRegistrationStatementToBecomeEffective" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_PeriodForRegistrationStatementToBecomeEffective"/>
  <xs:element name="RedemptionPricePerWarrant" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_RedemptionPricePerWarrant"/>
  <xs:element name="NumberOfDaysReceiveInvestorAfterTheDateOfClosingOfBusinessCombination" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_NumberOfDaysReceiveInvestorAfterTheDateOfClosingOfBusinessCombination"/>
  <xs:element name="RedemptionPeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_RedemptionPeriod"/>
  <xs:element name="ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsStockPriceTrigger" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsStockPriceTrigger"/>
  <xs:element name="ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsThresholdTradingDays" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsThresholdTradingDays"/>
  <xs:element name="ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsConsecutiveTradingDays" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ClassOfWarrantOrRightRedemptionOfWarrantsOrRightsConsecutiveTradingDays"/>
  <xs:element name="ExchangeRatio" type="xbrli:pureItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ExchangeRatio"/>
  <xs:element name="NumberOfDaysReceiveInvestorAfterTheDateOfClosingOfBusinessComnination" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_NumberOfDaysReceiveInvestorAfterTheDateOfClosingOfBusinessComnination"/>
  <xs:element name="StockBasedCompensationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_StockBasedCompensationDetailsTable"/>
  <xs:element name="PurchaseOfCommonShares" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="esla_PurchaseOfCommonShares"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsOptions" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsOptions"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentUnvestedCompensationCost" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_ShareBasedCompensationArrangementByShareBasedPaymentUnvestedCompensationCost"/>
  <xs:element name="EmploymentServicePeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_EmploymentServicePeriod"/>
  <xs:element name="ReverseRecapitalizationsExchangeRatio" type="xbrli:decimalItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ReverseRecapitalizationsExchangeRatio"/>
  <xs:element name="LeasesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_LeasesDetailsTable"/>
  <xs:element name="LeasesDetailsLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_LeasesDetailsLineItems"/>
  <xs:element name="SubsequentEventsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_SubsequentEventsDetailsTable"/>
  <xs:element name="SubleaseFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_SubleaseFee"/>
  <xs:element name="AdditionalMilestoneFee" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="esla_AdditionalMilestoneFee"/>
  <xs:element name="ReverseRecapitalizationDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_ReverseRecapitalizationDetailsTable"/>
  <xs:element name="ProceedsFromTheReverseRecapitalization" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_ProceedsFromTheReverseRecapitalization"/>
  <xs:element name="ReverseRecapitalizationExchangeRatio" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ReverseRecapitalizationExchangeRatio"/>
  <xs:element name="ExtensionNoteReceivableDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_ExtensionNoteReceivableDetailsTable"/>
  <xs:element name="ExtensionNoteReceivableCurrent" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="esla_ExtensionNoteReceivableCurrent"/>
  <xs:element name="PromissoryNoteDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_PromissoryNoteDetailsTable"/>
  <xs:element name="IncomeTaxesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="esla_IncomeTaxesDetailsTable"/>
  <xs:element name="AmortizedOverPeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_AmortizedOverPeriod"/>
  <xs:element name="AfterReverseRecapitalizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_AfterReverseRecapitalizationMember"/>
  <xs:element name="BeforeReverseRecapitalizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_BeforeReverseRecapitalizationMember"/>
  <xs:element name="BusinessCombinationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_BusinessCombinationMember"/>
  <xs:element name="CollaborationAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_CollaborationAgreementMember"/>
  <xs:element name="ConsultingAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ConsultingAgreementMember"/>
  <xs:element name="EquityLineSharesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_EquityLineSharesMember"/>
  <xs:element name="EstrellaBiopharmaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_EstrellaBiopharmaMember"/>
  <xs:element name="EstrellaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_EstrellaMember"/>
  <xs:element name="EurekaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_EurekaMember"/>
  <xs:element name="ExtensionNotesMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ExtensionNotesMember"/>
  <xs:element name="FounderShares1Member" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_FounderShares1Member"/>
  <xs:element name="HongbinZhangMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_HongbinZhangMember"/>
  <xs:element name="InvestorsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_InvestorsMember"/>
  <xs:element name="LicenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_LicenseAgreementMember"/>
  <xs:element name="NewEstrellasCapitalizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_NewEstrellasCapitalizationMember"/>
  <xs:element name="OperatingLeaseMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_OperatingLeaseMember"/>
  <xs:element name="PIPEInvestmentMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_PIPEInvestmentMember"/>
  <xs:element name="PlentifulLimitedAndLianheWorldMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_PlentifulLimitedAndLianheWorldMember"/>
  <xs:element name="PublicWarrantsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_PublicWarrantsMember"/>
  <xs:element name="ReverseRecapitalizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ReverseRecapitalizationMember"/>
  <xs:element name="SecuritiesInvestorProtectionCorporationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_SecuritiesInvestorProtectionCorporationMember"/>
  <xs:element name="SecuritiesPurchaseAgreementsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_SecuritiesPurchaseAgreementsMember"/>
  <xs:element name="SeriesAAPreferredStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_SeriesAAPreferredStockMember"/>
  <xs:element name="ServicesAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ServicesAgreementMember"/>
  <xs:element name="StandardInsuranceCoverageMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_StandardInsuranceCoverageMember"/>
  <xs:element name="StatementofWorkMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_StatementofWorkMember"/>
  <xs:element name="StockPurchaseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_StockPurchaseAgreementMember"/>
  <xs:element name="StockRepurchaseProgramMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_StockRepurchaseProgramMember"/>
  <xs:element name="SubscriptionAgreementsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_SubscriptionAgreementsMember"/>
  <xs:element name="TransitionPeriodMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_TransitionPeriodMember"/>
  <xs:element name="TwoThousandAndTwentyThreeOmnibusIncentivePlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_TwoThousandAndTwentyThreeOmnibusIncentivePlanMember"/>
  <xs:element name="TwoThousandAndTwentyThreePlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_TwoThousandAndTwentyThreePlanMember"/>
  <xs:element name="TwoThousandAndTwentyTwoPlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_TwoThousandAndTwentyTwoPlanMember"/>
  <xs:element name="UPTDMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_UPTDMember"/>
  <xs:element name="UPTDsCommonStockMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_UPTDsCommonStockMember"/>
  <xs:element name="UnsecuredNoteMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_UnsecuredNoteMember"/>
  <xs:element name="WhiteLionMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_WhiteLionMember"/>
  <xs:element name="officeLeaseContractMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_officeLeaseContractMember"/>
  <xs:element name="ExtensionNoteReceivableLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_ExtensionNoteReceivableLineItems"/>
  <xs:element name="TransitionPeriodComparativeDataAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_TransitionPeriodComparativeDataAbstract"/>
<!-- [WMV6][mgbZP8xVxLlF0tDNCR/Ieacy21xQMpTNk57JocPWoGF0tbsk9sKFEo2ewDhlz1HA/g1wfKKz5sCrAUVlgaJGLTVJUJjra6sBei8IOL52jsfOgcm7nEXIZ8C2qJ5E3met7NsfqRuWOpk5imZCLBc31wmDZjRnet8dMfzbYBKYOP8jufjCWvinHQgBGmyNx3H4UPwooLKQwZE/8IsjUiZIs1RvXEDMd3v6s/9FG6SptdQscSXlLo0QbZ6ir/YNz6Pk8I8F9JVoiZugBOek4EoHHzTOomlkkw28b1aRxtmSnMEhirA0gWrk1/OmnbNmGfhpdObtFCZyq8daW54pIyCk4hG2wz/5wnD3AQA/q7iSgiGD8ylBs/E4yaoJC5HrEtd1eObFfsWy+dMjUG/NsnysEPUmBiboXtvq] CSR-->
  <xs:element name="DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="esla_DocumentAndEntityInformationAbstract"/>
</xs:schema>
