Schedule I — Condensed Financial Information of Registrant - Condensed Statements of Operations and Comprehensive Loss (Details) - USD ($) |
12 Months Ended | ||
|---|---|---|---|
Dec. 31, 2025 |
Dec. 31, 2024 |
Dec. 31, 2023 |
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| Operating Expenses: | |||
| Research and development | $ (220,904,000) | $ (234,504,000) | $ (265,868,000) |
| Loss from operations | (229,434,000) | (282,117,000) | (366,573,000) |
| Interest income | 33,048,000 | 37,105,000 | 39,797,000 |
| Interest expenses | (5,209,000) | (2,254,000) | 0 |
| Other (expense) income, net | 3,540,000 | 5,300,000 | 7,006,000 |
| Net loss | (175,537,000) | (257,103,000) | (334,620,000) |
| Other comprehensive (loss) income, net of tax of nil: | |||
| Other comprehensive income, tax | 0 | 0 | 0 |
| Foreign currency translation adjustments | (20,818,000) | 12,889,000 | 11,941,000 |
| Comprehensive loss | (196,355,000) | (244,214,000) | (322,679,000) |
| Parent Company | |||
| Operating Expenses: | |||
| Research and development | (30,000) | (8,000) | (82,000) |
| General and administrative | (13,590,000) | (20,275,000) | (16,958,000) |
| Loss from operations | (13,620,000) | (20,283,000) | (17,040,000) |
| Interest income | 21,695,000 | 28,176,000 | 30,840,000 |
| Interest expenses | (90,000) | 0 | 0 |
| Other (expense) income, net | (1,145,000) | (5,438,000) | 4,029,000 |
| Profit before income tax and equity in loss of subsidiaries | 6,840,000 | 2,455,000 | 17,829,000 |
| Equity in loss of subsidiaries | (182,377,000) | (259,558,000) | (352,449,000) |
| Net loss | (175,537,000) | (257,103,000) | (334,620,000) |
| Other comprehensive (loss) income, net of tax of nil: | |||
| Other comprehensive income, tax | 0 | 0 | 0 |
| Foreign currency translation adjustments | (20,818,000) | 12,889,000 | 11,941,000 |
| Comprehensive loss | $ (196,355,000) | $ (244,214,000) | $ (322,679,000) |
| X | ||||||||||
- Definition Amount after tax of increase (decrease) in equity from transactions and other events and circumstances from net income and other comprehensive income, attributable to parent entity. Excludes changes in equity resulting from investments by owners and distributions to owners. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of income (loss) from continuing operations before deduction of income tax expense (benefit) and income (loss) attributable to noncontrolling interest, and addition of income (loss) from equity method investments. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount of income (loss) for proportionate share of equity method investee's income (loss). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of interest expense classified as nonoperating. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount after tax and reclassification adjustments of gain (loss) on foreign currency translation adjustments, foreign currency transactions designated and effective as economic hedges of a net investment in a foreign entity and intra-entity foreign currency transactions that are of a long-term-investment nature, attributable to parent entity. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Amount of tax expense (benefit) allocated to other comprehensive income (loss) attributable to parent entity. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of income (expense) related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount of expense for research and development. Includes, but is not limited to, cost for computer software product to be sold, leased, or otherwise marketed and writeoff of research and development assets acquired in transaction other than business combination or joint venture formation or both. Excludes write-down of intangible asset acquired in business combination or from joint venture formation or both, used in research and development activity. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Details
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