| Organization and Principal Activities Zai Lab Limited was incorporated on March 28, 2013 in the Cayman Islands as an exempted company with limited liability under the Companies Act of the Cayman Islands (as amended). Zai Lab Limited and its subsidiaries (collectively referred to as the “Company”) are focused on discovering, developing, and commercializing products that address medical conditions with significant unmet needs in the areas of oncology, immunology, neuroscience, and infectious disease. The Company’s principal operations and geographic markets are in Greater China. The Company has a substantial presence in Greater China and the United States. As of December 31, 2025, the Company’s significant operating subsidiaries were as follows: | | | | | | | | | | | | | | | | | | | | | | | | | | | | Name of Company | | Place of
Incorporation | | Date of
Incorporation | | Percentage of
Ownership | | Principal Activities | | Zai Lab (Hong Kong) Limited | | Hong Kong | | April 29, 2013 | | 100% | | Operating company for business development and R&D activities and commercialization of innovative medicines and device | | Zai Lab (Shanghai) Co., Ltd. | | Mainland
China | | January 6, 2014 | | 100% | | Development and commercialization of innovative medicines and devices | | Zai Lab (AUST) Pty. Ltd. | | Australia | | December 10, 2014 | | 100% | | Clinical trial activities | | Zai Lab (Suzhou) Co., Ltd. | | Mainland
China | | November 30, 2015 | | 100% | | Development and commercialization of innovative medicines | | Zai Biopharmaceutical (Suzhou) Co., Ltd. | | Mainland
China | | June 15, 2017 | | 100% | | Development and commercialization of innovative medicines | | Zai Lab (US) LLC | | United
States | | April 21, 2017 | | 100% | | Operating company for business development, R&D activities and certain business activities, including legal, compliance and communication functions of the Company | | Zai Lab International Trading (Shanghai) Co., Ltd. | | Mainland
China | | November 6, 2019 | | 100% | | Commercialization of innovative medicines and devices | | Zai Auto Immune (Hong Kong) Limited | | Hong Kong | | November 4, 2020 | | 100% | | Operating company for business development and R&D activities | | Zai Lab (Taiwan) Limited | | Taiwan | | December 10, 2020 | | 100% | | Commercialization of innovative medicines and devices | | Zai Lab Trading (Suzhou) Co., Ltd. | | Mainland
China | | October 27, 2020 | | 100% | | Commercialization of innovative medicines |
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