Insider Trading Arrangements |
3 Months Ended |
|---|---|
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Dec. 31, 2025
shares
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| Trading Arrangements, by Individual | |
| Non-Rule 10b5-1 Arrangement Adopted | false |
| Rule 10b5-1 Arrangement Terminated | false |
| Non-Rule 10b5-1 Arrangement Terminated | false |
| Dr. Samantha (Ying) Du [Member] | |
| Trading Arrangements, by Individual | |
| Material Terms of Trading Arrangement | On November 10, 2025, Dr. Samantha (Ying) Du, the Company’s Founder, Chief Executive officer, and Chairperson of the Board, adopted a new written Rule 10b5-1 trading arrangement, for (1) the acquisition and sale of up to 400,000 ADSs upon the exercise of previously awarded options that are scheduled to expire in 2026 and (2) for the acquisition of up to 261,092 ADSs upon the exercise of previously awarded options that are scheduled to expire in 2026. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than November 9, 2026.
|
| Name | Dr. Samantha (Ying) Du |
| Title | Founder, Chief Executive officer, and Chairperson of the Board |
| Rule 10b5-1 Arrangement Adopted | true |
| Adoption Date | November 10, 2025 |
| Expiration Date | November 9, 2026 |
| Arrangement Duration | 364 days |
| Rafael Amado [Member] | |
| Trading Arrangements, by Individual | |
| Material Terms of Trading Arrangement | On November 14, 2025, Rafael Amado, the Company’s President and Head of Global Research and Development, adopted a new written Rule 10b5-1 trading arrangement for the sale of up to 20,000 ADSs. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than December 17, 2026.
|
| Name | Rafael Amado |
| Title | President and Head of Global Research and Development |
| Rule 10b5-1 Arrangement Adopted | true |
| Adoption Date | November 14, 2025 |
| Expiration Date | December 17, 2026 |
| Arrangement Duration | 398 days |
| Aggregate Available | 20,000 |
| Richard Gaynor [Member] | |
| Trading Arrangements, by Individual | |
| Material Terms of Trading Arrangement | On December 16, 2025, Richard Gaynor, one of the Company’s directors, adopted a new written Rule 10b5-1 trading arrangement for the purchase of ADSs with a price of up to $99,000. This Rule 10b5-1 trading arrangement is scheduled to terminate no later than December 31, 2026.
|
| Name | Richard Gaynor |
| Title | directors |
| Rule 10b5-1 Arrangement Adopted | true |
| Adoption Date | December 16, 2025 |
| Expiration Date | December 31, 2026 |
| Arrangement Duration | 380 days |
| Aggregate Available | 99,000 |
| Dr. Du Trading Arrangement, Options One [Member] | Dr. Samantha (Ying) Du [Member] | |
| Trading Arrangements, by Individual | |
| Aggregate Available | 400,000 |
| Dr. Du Trading Arrangement, Options Two [Member] | Dr. Samantha (Ying) Du [Member] | |
| Trading Arrangements, by Individual | |
| Aggregate Available | 261,092 |