v3.25.4
Segment Information (Details)
$ in Thousands
12 Months Ended
Dec. 31, 2025
USD ($)
segment
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Segment Reporting [Abstract]      
Number of operating segments | segment 1    
Number of reportable segments | segment 1    
Segment Reporting Information [Line Items]      
Total research and development expenses $ 220,904 $ 234,504 $ 265,868
Total selling, general, and administrative expenses 277,605 298,741 281,608
Reportable Segment      
Segment Reporting Information [Line Items]      
Personnel compensation and related costs 87,894 106,154 115,749
Licensing fees 30,597 30,997 19,291
CROs/CMOs/Investigators expenses 73,763 69,870 103,333
Other costs 28,650 27,483 27,495
Total research and development expenses 220,904 234,504 265,868
Clinical programs 86,934 86,126 112,158
Pre-Clinical programs 24,293 31,913 17,356
Unallocated research and development expenses 109,677 116,465 136,354
Total selling, general, and administrative expenses 277,605 298,741 281,608
Selling and marketing expenses 187,562 190,367 169,555
General and administrative expenses 90,043 108,374 112,053
Reportable Segment | Selling, general and administrative      
Segment Reporting Information [Line Items]      
Personnel compensation and related costs 165,005 174,958 173,389
Other costs $ 112,600 $ 123,783 $ 108,219