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  <xs:element id="stm_CurrentTaxExpenseIncomeRelatedToPillarTwo" abstract="false" name="CurrentTaxExpenseIncomeRelatedToPillarTwo" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_EffectiveIncomeTaxRateReconciliationTaxCreditExpenseOther" abstract="false" name="EffectiveIncomeTaxRateReconciliationTaxCreditExpenseOther" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DefferredTaxAssetsOperatingLossCarryforwardsTaxCreditsAndOtherTaxAttributes" abstract="false" name="DefferredTaxAssetsOperatingLossCarryforwardsTaxCreditsAndOtherTaxAttributes" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_UnrecognizedTaxBenefitsAgainstExistingNetOperatingLosses" abstract="false" name="UnrecognizedTaxBenefitsAgainstExistingNetOperatingLosses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_UnrecognizedTaxBenefitsResultingInNetOperatingLossesCarryforward" abstract="false" name="UnrecognizedTaxBenefitsResultingInNetOperatingLossesCarryforward" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsIncreasedDepreciationIncentives" abstract="false" name="DeferredTaxAssetsIncreasedDepreciationIncentives" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOperatingLeaseLiabilities" abstract="false" name="DeferredTaxAssetsOperatingLeaseLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets" abstract="false" name="DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearOne" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearOne" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearTwo" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearThree" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearThree" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearFour" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearFour" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearFive" abstract="false" name="DeferredTaxAssetsOnTaxLossCarryforwardsAndInvestmentCreditsExpirationYearFive" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_UnrecognizedTaxBenefitsIncreaseDecreaseResultingFromForeignCurrencyTranslation" abstract="false" name="UnrecognizedTaxBenefitsIncreaseDecreaseResultingFromForeignCurrencyTranslation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_AmortizationOfFinancingCost" abstract="false" name="AmortizationOfFinancingCost" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_FoundryPurchaseMember" abstract="true" name="FoundryPurchaseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_PowerPurchaseAndMinimumEnergyMember" abstract="true" name="PowerPurchaseAndMinimumEnergyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_CloudServicesMember" abstract="true" name="CloudServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_NumberOfLawsuitsFiled" abstract="false" name="NumberOfLawsuitsFiled" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="stm_CurrencyCollarsMember" abstract="true" name="CurrencyCollarsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_OptionOneMember" abstract="true" name="OptionOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_ForeignExchangeForwardContractsTerm" abstract="false" name="ForeignExchangeForwardContractsTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="stm_ForeignCurrencyDerivativesMaturityPeriod" abstract="false" name="ForeignCurrencyDerivativesMaturityPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="stm_MaximumPercentageForResearchAndDevelopmentAndCorporateCostsOfForecastedTransactions" abstract="false" name="MaximumPercentageForResearchAndDevelopmentAndCorporateCostsOfForecastedTransactions" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="stm_MaximumPercentageForManufacturingCostsOfForecastedTransactions" abstract="false" name="MaximumPercentageForManufacturingCostsOfForecastedTransactions" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="stm_MaximumPercentageForDesignatedHedgedItemOfForecastedTransactions" abstract="false" name="MaximumPercentageForDesignatedHedgedItemOfForecastedTransactions" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="stm_HedgingExposureToVariabilityInFutureCashFlowsForForecastedTransactionOverPeriod" abstract="false" name="HedgingExposureToVariabilityInFutureCashFlowsForForecastedTransactionOverPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="stm_RealizedGainLossOnReductionInOperatingExpenses" abstract="false" name="RealizedGainLossOnReductionInOperatingExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_PeriodOfAccumulatedOtherComprehensiveIncomeLoss" abstract="false" name="PeriodOfAccumulatedOtherComprehensiveIncomeLoss" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="stm_MaximumPercentageOfOutstandingAmountPerInstrumentWithBank" abstract="false" name="MaximumPercentageOfOutstandingAmountPerInstrumentWithBank" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="stm_NumberOfCustomerAccountedMoreThanTenPercentAccountsReceivable" abstract="false" name="NumberOfCustomerAccountedMoreThanTenPercentAccountsReceivable" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="stm_MajorCustomerPercentageOfTradeAccountsReceivables" abstract="false" name="MajorCustomerPercentageOfTradeAccountsReceivables" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="stm_FairValueMeasurementWithUnobservableInputsReconciliationNonRecurringBasisAssetLiabilityValue" abstract="false" name="FairValueMeasurementWithUnobservableInputsReconciliationNonRecurringBasisAssetLiabilityValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_ImpairmentChargeOnInvestments" abstract="false" name="ImpairmentChargeOnInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DerivativeNotionalAmountForHedgeOnForecastedResearchAndDevelopmentAndOtherOperatingExpenses" abstract="false" name="DerivativeNotionalAmountForHedgeOnForecastedResearchAndDevelopmentAndOtherOperatingExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DerivativeNotionalAmountForHedgeOnForecastedManufacturingCosts" abstract="false" name="DerivativeNotionalAmountForHedgeOnForecastedManufacturingCosts" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_OtherPayablesAndAccruedLiabilitiesMember" abstract="true" name="OtherPayablesAndAccruedLiabilitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_GainLossDeferredInOtherComprehensiveIncomeOnDerivative" abstract="false" name="GainLossDeferredInOtherComprehensiveIncomeOnDerivative" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortion" abstract="false" name="DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortion" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_SeniorUnsecuredConvertibleBondsIssuedOnAugustFourTwoThousandAndTwentyMember" abstract="true" name="SeniorUnsecuredConvertibleBondsIssuedOnAugustFourTwoThousandAndTwentyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_SalesAndOtherServicesMember" abstract="true" name="SalesAndOtherServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_PurchasesAndOtherContributionsMember" abstract="true" name="PurchasesAndOtherContributionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_StFoundationMember" abstract="true" name="StFoundationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_NXPSemiconductorsMember" abstract="true" name="NXPSemiconductorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="stm_BusinessCombinationUpfrontPayment" abstract="false" name="BusinessCombinationUpfrontPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_ClassOfWarrantOrRightNumberOfTransactions" abstract="false" name="ClassOfWarrantOrRightNumberOfTransactions" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="stm_ValuationAllowancesAndReservesChargedToIncomeAndExpense" abstract="false" name="ValuationAllowancesAndReservesChargedToIncomeAndExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="stm_ValuationAllowancesAndReservesAdditionsDeductions" abstract="false" name="ValuationAllowancesAndReservesAdditionsDeductions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
