v3.25.4
STOCK-BASED COMPENSATION (Tables)
12 Months Ended
Dec. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Schedule stock-based compensation expense
The components of stock-based compensation expense for both equity and liability-classified awards recognized in our consolidated statements of operations was as follows:
Year Ended
(in thousands)
December 31, 2025
December 31, 2024
December 31, 2023
RSUs
$54,564 $29,774 $1,127 
ESPP
3,059 — — 
PSOs
660 1,514 577 
Cash-based equity awards
— 54,796 95,531 
Stock-based compensation expense, before taxes
58,283 86,084 97,235 
Related income tax benefits(13,708)(20,890)(23,455)
Stock-based compensation expense, net of taxes
$44,575 $65,194 $73,780 
Stock-based compensation expense for both equity and liability-classified awards, reported in our consolidated statements of operations was as follows:
Year Ended
(in thousands)
December 31, 2025
December 31, 2024
December 31, 2023
Cost of screening revenue (exclusive of amortization of intangible assets)
$2,226 $1,724 $1,932 
Cost of development services revenue36 230 38 
Research and development15,986 30,701 39,792 
Sales and marketing10,871 15,310 17,506 
General and administrative29,164 38,119 37,967 
Stock-based compensation expense, before taxes
58,283 86,084 97,235 
Related income tax benefits(13,708)(20,890)(23,455)
Stock-based compensation expense, net of taxes
$44,575 $65,194 $73,780 
Schedule of ESPP fair value assumptions
Unamortized compensation cost and weighted average service period of all unvested equity classified awards as of December 31, 2025 was as follows:

Unamortized Compensation Costs
Weighted Average Service Period
(in thousands)
(in years)
RSUs and PSUs
$76,895 1.5
PSOs
432 1.2
ESPP
1,719 0.4
Total unamortized compensation costs
$79,046 

A summary of the Company’s shares available for grant under the ESPP, was as follows:
Shares Available for Grant
(in thousands)
Balance as of December 31, 2024414,021
Annual increase338,934
Issued(1)
(136,551)
Balance as of December 31, 2025616,404
(1) Represent $4.5 million in cash received for the issuance of common stock under the ESPP
PSOs activity, issued under the 2024 Plan, were as follows:
Performance Options
Weighted-Average Exercise Price Per Share
Weighted-Average Contractual Term
(in thousands)
(in years)
Outstanding at December 31, 2025104$13.534.2
Vested and Exercisable at December 31, 202523$14.004.2
The fair value of employee stock purchase rights under the ESPP have been estimated with the following assumptions using the Black-Scholes-Merton option-pricing model:
December 31, 2025
Weighted-average assumptions:
Expected life (in years)
0.5
Risk-free interest rate
4.0%
Expected volatility
97.4%
Expected dividend
—%
Weighted-average estimated grant date fair value per share$59.31
Schedule of shares available for grant activity
A summary of the Company’s shares available for grant under the 2024 Plan, was as follows:
Shares Available for Grant
(in thousands)
Balance as of December 31, 2024479,339
Annual increase1,694,670
Awarded(2,152,456)
Forfeited491,833
Balance as of December 31, 2025513,386
Schedule of RSUs, PSUs, and DSUs activity
A summary of the Company’s RSUs, PSUs, and DSUs, issued under the 2024 Plan and 2024 Inducement Award Plan, were as follows:
Restricted Stock Units(1)
Weighted-Average Grant-Date Fair Value Per Share
(in thousands)
Outstanding at January 1, 2024—$—
Conversion6,485$15.37
Awarded2,833$13.07
Released(2,844)$15.37
Forfeited(951)$15.22
Outstanding at December 31, 20245,523$14.22
Awarded(1)
2,407$40.79
Released(2,491)$15.21
Forfeited(576)$22.83
Outstanding at December 31, 20254,863$25.84
(1) Includes 31,000 PSU awarded and 30,865 DSUs vested but unreleased related to three directors that had elected to defer their 2025 cash fees and two directors that had elected to defer release of their equity awards
Schedule of equity award activity
Cash-Based Equity Award activity for the periods presented was as follows:
Year Ended
(in thousands)
December 31,
2024
Beginning balance$292,189 
Granted66,864 
Cancelled(11,751)
Vested and paid in cash(53,807)
Change in fair value(9,535)
Conversion of outstanding awards to GRAIL RSUs(283,960)
Outstanding balance$—