SEGMENT INFORMATION - Schedule of segment revenue by geographic area (Details) - USD ($) $ in Thousands |
12 Months Ended | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Dec. 31, 2025 |
Dec. 31, 2024 |
Dec. 31, 2023 |
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| Revenue | |||||||||
| Total revenue | $ 147,172 | $ 125,595 | $ 93,105 | ||||||
| Costs and operating expenses | |||||||||
| Stock-based compensation | 58,283 | 86,084 | 97,235 | ||||||
| Goodwill and intangible assets impairment | 28,000 | 1,420,936 | 718,466 | ||||||
| Total costs and operating expenses | 709,335 | 2,314,753 | 1,608,487 | ||||||
| Loss from operations | (562,163) | (2,189,158) | (1,515,382) | ||||||
| Other income (expense): | |||||||||
| Interest income | 28,652 | 26,733 | 7,954 | ||||||
| Other income (expense), net | (993) | 64 | (208) | ||||||
| Benefit from income taxes | 126,153 | 135,356 | 41,951 | ||||||
| Net loss | (408,351) | (2,027,005) | (1,465,685) | ||||||
| Depreciation | 18,010 | 19,723 | 20,364 | ||||||
| Reportable Segment | |||||||||
| Costs and operating expenses | |||||||||
| Compensation | 231,188 | 314,042 | 311,375 | ||||||
| Depreciation and intangible assets amortization expense | 149,794 | 153,228 | 148,920 | ||||||
| Stock-based compensation | 56,021 | 84,130 | 95,265 | ||||||
| Professional services | 36,821 | 63,443 | 48,994 | ||||||
| Clinical studies | 28,012 | 43,890 | 54,590 | ||||||
| Goodwill and intangible assets impairment | 28,000 | 1,420,936 | 718,466 | ||||||
| Cloud computing and information technology | 25,019 | 30,233 | 31,868 | ||||||
| Facilities | 21,666 | 25,983 | 30,276 | ||||||
| Laboratory supplies and research collaborations | 12,802 | 41,341 | 41,863 | ||||||
| Other segment expenses | 44,156 | 67,799 | 72,043 | ||||||
| Total costs and operating expenses | 709,335 | 2,314,753 | 1,608,487 | ||||||
| Loss from operations | (562,163) | (2,189,158) | (1,515,382) | ||||||
| Other income (expense): | |||||||||
| Interest income | 28,652 | 26,733 | 7,954 | ||||||
| Other income (expense), net | (993) | 64 | (208) | ||||||
| Benefit from income taxes | 126,153 | 135,356 | 41,951 | ||||||
| Net loss | (408,351) | (2,027,005) | (1,465,685) | ||||||
| Depreciation | 6,600 | 4,800 | 9,800 | ||||||
| Screening revenue | |||||||||
| Revenue | |||||||||
| Total revenue | [1] | 138,601 | 108,627 | 74,999 | |||||
| Costs and operating expenses | |||||||||
| Cost of revenue | [2] | 73,251 | 63,284 | 47,966 | |||||
| Development Services | |||||||||
| Revenue | |||||||||
| Total revenue | 8,571 | 16,968 | 18,106 | ||||||
| Costs and operating expenses | |||||||||
| Cost of revenue | [3] | $ 2,605 | $ 6,444 | $ 6,861 | |||||
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- Definition Clinical Studies Expense No definition available.
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| X | ||||||||||
- Definition Cloud Computing And Information Technology Expense No definition available.
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| X | ||||||||||
- Definition Laboratory Supplies And Research Collaborations Expense No definition available.
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| X | ||||||||||
- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Total costs of sales and operating expenses for the period. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Total loss recognized during the period from the impairment of goodwill plus the loss recognized in the period resulting from the impairment of the carrying amount of intangible assets, other than goodwill. No definition available.
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| X | ||||||||||
- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition Amount of expense for salary, wage, profit sharing; incentive and equity-based compensation; and other employee benefit. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Amount of operating lease expense. Excludes sublease income. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Amount of income (expense) related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- Definition Professional and contract service expense includes cost reimbursements for support services related to contracted projects, outsourced management, technical and staff support. No definition available.
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| X | ||||||||||
- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Amount of other expense (income) and loss (gain) calculated as difference between segment revenue and separately disclosed expense category to arrive at segment profit (loss). Reference 1: http://www.xbrl.org/2003/role/exampleRef
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