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  <xs:element id="valn_BorrowingFacilitiesMaximumBorrowingCapacity" abstract="false" name="BorrowingFacilitiesMaximumBorrowingCapacity" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_VaccinesHoldingsSwedenABMember" abstract="true" name="VaccinesHoldingsSwedenABMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaAustriaGmbHMember" abstract="true" name="ValnevaAustriaGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaCanadaIncMember" abstract="true" name="ValnevaCanadaIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaFranceSASMember" abstract="true" name="ValnevaFranceSASMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaScotlandLtdMember" abstract="true" name="ValnevaScotlandLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaSwedenABMember" abstract="true" name="ValnevaSwedenABMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaUKLtdMember" abstract="true" name="ValnevaUKLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaUSAIncMember" abstract="true" name="ValnevaUSAIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_VBC3ErrichtungsGmbHMember" abstract="true" name="VBC3ErrichtungsGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RefundLiabilitiesUndiscountedCashFlows" abstract="false" name="RefundLiabilitiesUndiscountedCashFlows" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_TaxAndEmployeeRelatedLiabilitiesUndiscountedCashFlows" abstract="false" name="TaxAndEmployeeRelatedLiabilitiesUndiscountedCashFlows" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="valn_OtherRevenueFromContractWithCustomers" abstract="false" name="OtherRevenueFromContractWithCustomers" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherRevenueNotFromContractsWithCustomers" abstract="false" name="OtherRevenueNotFromContractsWithCustomers" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PfizerIncMember" abstract="true" name="PfizerIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_SerumInstituteOfIndiaMember" abstract="true" name="SerumInstituteOfIndiaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_U.S.MilitaryMember" abstract="true" name="U.S.MilitaryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_LymeVLA15Member" abstract="true" name="LymeVLA15Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_DUKORALMember" abstract="true" name="DUKORALMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IXCHIQChikungunyaVLA1553Member" abstract="true" name="IXCHIQChikungunyaVLA1553Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ThirdPartyProductsMember" abstract="true" name="ThirdPartyProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RevenuesFromShippingAndHandlingMember" abstract="true" name="RevenuesFromShippingAndHandlingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_MilestonePaymentLicencesMember" abstract="true" name="MilestonePaymentLicencesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OtherServicesMember" abstract="true" name="OtherServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AmendedCollaborationAndLicenseAgreementMember" abstract="true" name="AmendedCollaborationAndLicenseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_MasterCollaborationAndLicenseAgreementMember" abstract="true" name="MasterCollaborationAndLicenseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ConcentrationRiskByCustomerMember" abstract="true" name="ConcentrationRiskByCustomerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OneCustomerMember" abstract="true" name="OneCustomerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_CustomersRepresentingMoreThan10OfSalesMember" abstract="true" name="CustomersRepresentingMoreThan10OfSalesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RevenueNumberOfPerformanceObligations" abstract="false" name="RevenueNumberOfPerformanceObligations" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_SharedDevelopmentCostsPercentageIncurred" abstract="false" name="SharedDevelopmentCostsPercentageIncurred" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_MilestonePaymentsDevelopmentAndCommercialization" abstract="false" name="MilestonePaymentsDevelopmentAndCommercialization" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RoyaltiesPercentage" abstract="false" name="RoyaltiesPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_PotentialFutureMilestonePaymentsSalesTargets" abstract="false" name="PotentialFutureMilestonePaymentsSalesTargets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenueFromSalesOfGood" abstract="false" name="IncreaseDecreaseInRevenueFromSalesOfGood" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenueFromSalesOfGoodsPercentage" abstract="false" name="IncreaseDecreaseInRevenueFromSalesOfGoodsPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_IncreaseDecreaseInOtherRevenueFromContractWithCustomers" abstract="false" name="IncreaseDecreaseInOtherRevenueFromContractWithCustomers" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenue" abstract="false" name="IncreaseDecreaseInRevenue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInSalesOfGoodsPercentage" abstract="false" name="IncreaseDecreaseInSalesOfGoodsPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="valn_NumberOfMajorCustomers" abstract="false" name="NumberOfMajorCustomers" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
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  <xs:element id="valn_CovidVLA2001ProductMember" abstract="true" name="CovidVLA2001ProductMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RoyaltiesReceivedMember" abstract="true" name="RoyaltiesReceivedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RDWorkAndAdditionalSupportServicesMember" abstract="true" name="RDWorkAndAdditionalSupportServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ThereofCOVID19Member" abstract="true" name="ThereofCOVID19Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_NordicsMember" abstract="true" name="NordicsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OtherEuropeMember" abstract="true" name="OtherEuropeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RestOfWorldMember" abstract="true" name="RestOfWorldMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ConsultingAndOtherPurchasedServices" abstract="false" name="ConsultingAndOtherPurchasedServices" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_CostOfServicesAndChangeInInventory" abstract="false" name="CostOfServicesAndChangeInInventory" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_EmployeeBenefitExpenseOtherThanShareBasedCompensation" abstract="false" name="EmployeeBenefitExpenseOtherThanShareBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_BuildingAndEnergyCosts" abstract="false" name="BuildingAndEnergyCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_SupplyOfficeAndITCosts" abstract="false" name="SupplyOfficeAndITCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_LicenseFeesAndRoyalties" abstract="false" name="LicenseFeesAndRoyalties" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_WarehousingAndDistributionCosts" abstract="false" name="WarehousingAndDistributionCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_TravelAndTransportationExpenses" abstract="false" name="TravelAndTransportationExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInOperatingExpenses" abstract="false" name="IncreaseDecreaseInOperatingExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInCostOfServicesAndChangeInInventory" abstract="false" name="IncreaseDecreaseInCostOfServicesAndChangeInInventory" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRawMaterialsAndConsumablesUsed" abstract="false" name="IncreaseDecreaseInRawMaterialsAndConsumablesUsed" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInDepreciationAndAmortizationAndImpairment" abstract="false" name="IncreaseDecreaseInDepreciationAndAmortizationAndImpairment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ClassOfAuditorsAxis" abstract="true" name="ClassOfAuditorsAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
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  <xs:element id="valn_StatutoryAuditorsNetworkMember" abstract="true" name="StatutoryAuditorsNetworkMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_DeloitteAssociesMember" abstract="true" name="DeloitteAssociesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AuditorsRemunerationForAuditServicesPercentage" abstract="false" name="AuditorsRemunerationForAuditServicesPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_AuditorsRemunerationForAuditRelatedFees" abstract="false" name="AuditorsRemunerationForAuditRelatedFees" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="valn_AuditorsRemunerationForTaxServicesPercentage" abstract="false" name="AuditorsRemunerationForTaxServicesPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_AuditorsRemunerationForOtherServicesPercentage" abstract="false" name="AuditorsRemunerationForOtherServicesPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_AuditorsRemunerationPercentage" abstract="false" name="AuditorsRemunerationPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_SocialSecurityContributionsExpenseCredit" abstract="false" name="SocialSecurityContributionsExpenseCredit" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_TrainingAndEducationExpenses" abstract="false" name="TrainingAndEducationExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInEmployeeBenefitsExpense" abstract="false" name="IncreaseDecreaseInEmployeeBenefitsExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="valn_IncreaseDecreaseInSocialSecurityContributionsTerminationBenefits" abstract="false" name="IncreaseDecreaseInSocialSecurityContributionsTerminationBenefits" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionReleasedRecognizedEmployerContributionCostsOnShareBasedCompensationPlans" abstract="false" name="ProvisionReleasedRecognizedEmployerContributionCostsOnShareBasedCompensationPlans" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ScottishEnterpriseMember" abstract="true" name="ScottishEnterpriseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_CoalitionForEpidemicPreparednessInnovationsCEPIMember" abstract="true" name="CoalitionForEpidemicPreparednessInnovationsCEPIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_StrategicPartnershipAgreementMember" abstract="true" name="StrategicPartnershipAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_PartneringSecondAgreementWithCEPIMember" abstract="true" name="PartneringSecondAgreementWithCEPIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ScotlandMember" abstract="true" name="ScotlandMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_TransactionCostsOnSaleOfPriorityReviewVoucher" abstract="false" name="TransactionCostsOnSaleOfPriorityReviewVoucher" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInOtherOperatingIncomeExpense" abstract="false" name="IncreaseDecreaseInOtherOperatingIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInOtherOperatingIncomeExpensePercentage" abstract="false" name="IncreaseDecreaseInOtherOperatingIncomeExpensePercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_PartnershipMaximumAmountPayableUnderContract" abstract="false" name="PartnershipMaximumAmountPayableUnderContract" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AmountPaidUnderContract" abstract="false" name="AmountPaidUnderContract" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="valn_ResearchAndDevelopmentTaxCredit" abstract="false" name="ResearchAndDevelopmentTaxCredit" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProfitLossFromRevaluationOfLeaseAgreements" abstract="false" name="ProfitLossFromRevaluationOfLeaseAgreements" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="valn_FinanceIncomeAbstract" abstract="true" name="FinanceIncomeAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_RealizedGainsFromCashAndCashEquivalents" abstract="false" name="RealizedGainsFromCashAndCashEquivalents" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_FinanceExpensesAbstract" abstract="true" name="FinanceExpensesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_InterestExpenseOnLoans" abstract="false" name="InterestExpenseOnLoans" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_InterestExpenseOnRefundLiabilities" abstract="false" name="InterestExpenseOnRefundLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherInterestExpense" abstract="false" name="OtherInterestExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_InterestExpenseAndRelatedFees" abstract="false" name="InterestExpenseAndRelatedFees" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExchangeRateRevaluationOfUSDollarAgainstEuro" abstract="false" name="ExchangeRateRevaluationOfUSDollarAgainstEuro" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_CURRENTTAXABSTRACTAbstract" abstract="true" name="CURRENTTAXABSTRACTAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_DEFERREDTAXAbstract" abstract="true" name="DEFERREDTAXAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_TaxEffectOfDeferredTaxAssetNotRecognized" abstract="false" name="TaxEffectOfDeferredTaxAssetNotRecognized" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="valn_TrancheThreeMember" abstract="true" name="TrancheThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsNumberOfSuccessivePlans" abstract="false" name="ShareBasedPaymentArrangementsNumberOfSuccessivePlans" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsNumberOfEqualTranchesToExerciseAwards" abstract="false" name="ShareBasedPaymentArrangementsNumberOfEqualTranchesToExerciseAwards" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsVestingPeriod" abstract="false" name="ShareBasedPaymentArrangementsVestingPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsExpirationPeriod" abstract="false" name="ShareBasedPaymentArrangementsExpirationPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsVestingDueToTakeoverMinimumPercentage" abstract="false" name="ShareBasedPaymentArrangementsVestingDueToTakeoverMinimumPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_WeightedAverageFairValuePriceAtMeasurementDateShareOptionsGranted" abstract="false" name="WeightedAverageFairValuePriceAtMeasurementDateShareOptionsGranted" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="valn_NumberOfAwardsAbstract" abstract="true" name="NumberOfAwardsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_NumberOfAwardsAvailableAbstract" abstract="true" name="NumberOfAwardsAvailableAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_NumberOfSharesOptionsOutstandingInShareBasedPaymentArrangementSharesAvailable" abstract="false" name="NumberOfSharesOptionsOutstandingInShareBasedPaymentArrangementSharesAvailable" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_NumberOfSharesOptionsGrantedInShareBasedPaymentArrangementSharesAvailable" abstract="false" name="NumberOfSharesOptionsGrantedInShareBasedPaymentArrangementSharesAvailable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_NumberOfSharesOptionsExpiredInShareBasedPaymentArrangementSharesAvailable" abstract="false" name="NumberOfSharesOptionsExpiredInShareBasedPaymentArrangementSharesAvailable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_NumberOfSharesOptionsForfeitedInShareBasedPaymentArrangementSharesAvailable" abstract="false" name="NumberOfSharesOptionsForfeitedInShareBasedPaymentArrangementSharesAvailable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_NumberOfSharesOptionsExercisedInShareBasedPaymentArrangementSharesAvailable" abstract="false" name="NumberOfSharesOptionsExercisedInShareBasedPaymentArrangementSharesAvailable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_NumberOfSharesOptionsExercisableInShareBasedPaymentArrangementSharesAvailable" abstract="false" name="NumberOfSharesOptionsExercisableInShareBasedPaymentArrangementSharesAvailable" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_WeightedAverageExercisePriceOfAwardsAbstract" abstract="true" name="WeightedAverageExercisePriceOfAwardsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_AwardsMaturing2025Member" abstract="true" name="AwardsMaturing2025Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2026Member" abstract="true" name="AwardsMaturing2026Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2027Member" abstract="true" name="AwardsMaturing2027Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2029Member" abstract="true" name="AwardsMaturing2029Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2032Member" abstract="true" name="AwardsMaturing2032Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2033Member" abstract="true" name="AwardsMaturing2033Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2034Member" abstract="true" name="AwardsMaturing2034Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AwardsMaturing2035Member" abstract="true" name="AwardsMaturing2035Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsNumberOfTranches" abstract="false" name="ShareBasedPaymentArrangementsNumberOfTranches" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsNumberOfTranchesRoundedDownIfTheThirdTrancheIsNotAWholeNumber" abstract="false" name="ShareBasedPaymentArrangementsNumberOfTranchesRoundedDownIfTheThirdTrancheIsNotAWholeNumber" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_ShareBasedPaymentArrangementsMinimumNumberOfVestedFreeSharesOfEachTranche" abstract="false" name="ShareBasedPaymentArrangementsMinimumNumberOfVestedFreeSharesOfEachTranche" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_ManagementBoardMember" abstract="true" name="ManagementBoardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_SeniorLeadershipGroupMember" abstract="true" name="SeniorLeadershipGroupMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_FreeOrdinarySharesProgramTypeAxis" abstract="true" name="FreeOrdinarySharesProgramTypeAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="valn_FreeOrdinarySharesProgramTypeDomain" abstract="true" name="FreeOrdinarySharesProgramTypeDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_FreeOrdinarySharesSubjectToPerformanceConditionsMember" abstract="true" name="FreeOrdinarySharesSubjectToPerformanceConditionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_FreeOrdinarySharesNotSubjectToPerformanceConditionsMember" abstract="true" name="FreeOrdinarySharesNotSubjectToPerformanceConditionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ProvisionsForEmployeeCommitmentsPhantomShares" abstract="false" name="ProvisionsForEmployeeCommitmentsPhantomShares" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_NonCurrentBorrowingsAbstract" abstract="true" name="NonCurrentBorrowingsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_DebenturesAndOtherLoansNonCurrent" abstract="false" name="DebenturesAndOtherLoansNonCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_CurrentBorrowingsAbstract" abstract="true" name="CurrentBorrowingsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_DebenturesAndOtherLoansCurrent" abstract="false" name="DebenturesAndOtherLoansCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ResearchTaxCreditMember" abstract="true" name="ResearchTaxCreditMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_CEPIMember" abstract="true" name="CEPIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_BorrowingsEffectiveInterestRate" abstract="false" name="BorrowingsEffectiveInterestRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_BorrowingsTransactionCosts" abstract="false" name="BorrowingsTransactionCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PharmakonLoanAgreementDue2030AndAmendedDebtFinancingAgreementDue2028Member" abstract="true" name="PharmakonLoanAgreementDue2030AndAmendedDebtFinancingAgreementDue2028Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_GrossProceedsFromBorrowingsClassifiedAsFinancingActivities" abstract="false" name="GrossProceedsFromBorrowingsClassifiedAsFinancingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseThroughTransactionCostsBorrowings" abstract="false" name="IncreaseDecreaseThroughTransactionCostsBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AccruedInterestOnBorrowings" abstract="false" name="AccruedInterestOnBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseThroughExchangeRateDifferenceBorrowings" abstract="false" name="IncreaseDecreaseThroughExchangeRateDifferenceBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_EmployeeRelatedLiabilities" abstract="false" name="EmployeeRelatedLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_SocialSecurityAndOtherTaxes" abstract="false" name="SocialSecurityAndOtherTaxes" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_TaxAndEmployeeRelatedLiabilities" abstract="false" name="TaxAndEmployeeRelatedLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_NonCurrentTaxAndEmployeeRelatedLiabilities" abstract="false" name="NonCurrentTaxAndEmployeeRelatedLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseThroughNewContractLease" abstract="false" name="IncreaseThroughNewContractLease" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseThroughRevaluationDueToVariablePaymentsNotRightOfUseAssets" abstract="false" name="IncreaseThroughRevaluationDueToVariablePaymentsNotRightOfUseAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_DecreaseThroughPaymentLease" abstract="false" name="DecreaseThroughPaymentLease" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseThroughInterestExpensesLease" abstract="false" name="IncreaseThroughInterestExpensesLease" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseThroughNetExchangeDifferencesLease" abstract="false" name="IncreaseDecreaseThroughNetExchangeDifferencesLease" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInLeaseLiabilities" abstract="false" name="IncreaseDecreaseInLeaseLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_DisclosureOfDetailedInformationAboutLeasesPaymentsTable" abstract="true" name="DisclosureOfDetailedInformationAboutLeasesPaymentsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="valn_DisclosureOfDetailedInformationAboutLeasesPaymentsLineItems" abstract="true" name="DisclosureOfDetailedInformationAboutLeasesPaymentsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_OtherCurrenciesMember" abstract="true" name="OtherCurrenciesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RevenueRecognitionContractLiabilities" abstract="false" name="RevenueRecognitionContractLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RevenueRecognitionRedemption" abstract="false" name="RevenueRecognitionRedemption" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdditionsContractLiabilities" abstract="false" name="AdditionsContractLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExchangeRateDifferencesContractLiabilities" abstract="false" name="ExchangeRateDifferencesContractLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_DoDDistributionAgreementMember" abstract="true" name="DoDDistributionAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AdditionsRefundLiability" abstract="false" name="AdditionsRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PaymentsRefundLiability" abstract="false" name="PaymentsRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherReleasesRefundLiability" abstract="false" name="OtherReleasesRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RevenueRecognitionRefundLiability" abstract="false" name="RevenueRecognitionRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_InterestExpenseCapitalizedRefundLiability" abstract="false" name="InterestExpenseCapitalizedRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExchangeRateDifferenceRefundLiability" abstract="false" name="ExchangeRateDifferenceRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_GSKMember" abstract="true" name="GSKMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_SupplyAgreementMember" abstract="true" name="SupplyAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RefundProvisionReturnProvisionAndRebates" abstract="false" name="RefundProvisionReturnProvisionAndRebates" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionsForEmployerContributionCostsOnShareBasedCompensationPlans" abstract="false" name="ProvisionsForEmployerContributionCostsOnShareBasedCompensationPlans" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionsForRetirementTerminationBenefits" abstract="false" name="ProvisionsForRetirementTerminationBenefits" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionsForLeavingIndemnitiesAndRestructurings" abstract="false" name="ProvisionsForLeavingIndemnitiesAndRestructurings" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ClosingSharePrice" abstract="false" name="ClosingSharePrice" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="valn_ActuarialAssumptionOfExpectedRatesOfTurnover" abstract="false" name="ActuarialAssumptionOfExpectedRatesOfTurnover" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_ActuarialAssumptionOfExpectedRatesOfSocialSecurityRate" abstract="false" name="ActuarialAssumptionOfExpectedRatesOfSocialSecurityRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_MiscellaneousLiabilities" abstract="false" name="MiscellaneousLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProceedsFromResilienceGrant" abstract="false" name="ProceedsFromResilienceGrant" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossFixedAssetsAndIntangibleAssets" abstract="false" name="AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossFixedAssetsAndIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncomeTaxExpenseIncome" abstract="false" name="AdjustmentsForIncomeTaxExpenseIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForGainLossOnDisposalsOfPropertyPlantAndEquipmentAndIntangibleAssets" abstract="false" name="AdjustmentsForGainLossOnDisposalsOfPropertyPlantAndEquipmentAndIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentForGainlossFromMMFInvestments" abstract="false" name="AdjustmentForGainlossFromMMFInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForEmployerContributionCostsOnShareBasedCompensationPlans" abstract="false" name="AdjustmentsForEmployerContributionCostsOnShareBasedCompensationPlans" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherAdjustmentsForNonCashIncomeExpense" abstract="false" name="OtherAdjustmentsForNonCashIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ChangesInNonCurrentOperatingAssetsAndLiabilitiesExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" abstract="true" name="ChangesInNonCurrentOperatingAssetsAndLiabilitiesExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_AdjustmentsForDecreaseIncreaseInOtherNonCurrentAssets" abstract="false" name="AdjustmentsForDecreaseIncreaseInOtherNonCurrentAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInLongTermRefundLiabilities" abstract="false" name="AdjustmentsForIncreaseDecreaseInLongTermRefundLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInOtherNonCurrentLiabilitiesAndProvisions" abstract="false" name="AdjustmentsForIncreaseDecreaseInOtherNonCurrentLiabilitiesAndProvisions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ChangesInWorkingCapitalExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" abstract="true" name="ChangesInWorkingCapitalExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInRefundLiabilities" abstract="false" name="AdjustmentsForIncreaseDecreaseInRefundLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInOtherPayablesAndProvisions" abstract="false" name="AdjustmentsForIncreaseDecreaseInOtherPayablesAndProvisions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_DecreaseThroughTransactionCostsLiabilitiesArisingFromFinancingActivities" abstract="false" name="DecreaseThroughTransactionCostsLiabilitiesArisingFromFinancingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseThroughAccruedInterestLiabilitiesArisingFromFinancingActivities" abstract="false" name="IncreaseThroughAccruedInterestLiabilitiesArisingFromFinancingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_DecreaseThroughPaymentOfInterestLiabilitiesArisingFromFinancingActivities" abstract="false" name="DecreaseThroughPaymentOfInterestLiabilitiesArisingFromFinancingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_MajorLitigationMember" abstract="true" name="MajorLitigationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ContractualRDCommitments" abstract="false" name="ContractualRDCommitments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdditionalCashCompensationPerShare" abstract="false" name="AdditionalCashCompensationPerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="valn_NumberOfAppeals" abstract="false" name="NumberOfAppeals" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_NumberOfShareholdersWhoAppealedTheDecision" abstract="false" name="NumberOfShareholdersWhoAppealedTheDecision" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_Royalties" abstract="false" name="Royalties" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherCommitments" abstract="false" name="OtherCommitments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_BankAccountsPledgedAsSecurityForLiabilities" abstract="false" name="BankAccountsPledgedAsSecurityForLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_GuaranteesAndPledges" abstract="false" name="GuaranteesAndPledges" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionOfServicesOperatingActivitiesRelatedPartyTransactions" abstract="false" name="ProvisionOfServicesOperatingActivitiesRelatedPartyTransactions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionOfServicesFinancingActivitiesRelatedPartyTransactions" abstract="false" name="ProvisionOfServicesFinancingActivitiesRelatedPartyTransactions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProvisionOfServicesRelatedPartyTransactions" abstract="false" name="ProvisionOfServicesRelatedPartyTransactions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExecutiveCommitteeFormerManagementBoardMember" abstract="true" name="ExecutiveCommitteeFormerManagementBoardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_BoardOfDirectorsMember" abstract="true" name="BoardOfDirectorsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_VitalMeatSASMember" abstract="true" name="VitalMeatSASMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_BPIFranceMember" abstract="true" name="BPIFranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_BorrowingsGrantedPercentageOfReceivables" abstract="false" name="BorrowingsGrantedPercentageOfReceivables" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_BorrowingsCommitmentFee" abstract="false" name="BorrowingsCommitmentFee" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_NumberOfAdditionalExecutiveCommitteeMembers" abstract="false" name="NumberOfAdditionalExecutiveCommitteeMembers" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_ResearchTaxCredit2022Member" abstract="true" name="ResearchTaxCredit2022Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ResearchTaxCredit2023Member" abstract="true" name="ResearchTaxCredit2023Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ResearchTaxCredit2024Member" abstract="true" name="ResearchTaxCredit2024Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
</xs:schema>
