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Period Type:

SHAREHOLDERS' EQUITY (Details)								1 Months Ended	12 Months Ended
SHAREHOLDERS' EQUITY (Details)	Oct. 14, 2025 USD ($)	Oct. 10, 2025 USD ($) $ / shares shares	Apr. 09, 2025	Apr. 08, 2025	Dec. 23, 2024 USD ($) $ / shares shares	Dec. 20, 2024 USD ($) $ / shares shares	Mar. 07, 2024 USD ($) $ / shares shares	Mar. 31, 2024	Dec. 31, 2025 USD ($) Y $ / shares shares	Dec. 31, 2024 USD ($) $ / shares shares	Dec. 31, 2023 USD ($)	Dec. 24, 2024 shares	Jan. 05, 2024 USD ($) $ / shares
SHAREHOLDERS' EQUITY
Ordinary shares, shares authorized									5,000,000,000	100,000,000
Ordinary shares, par value \| $ / shares									$ 0	$ 0
Proceeds from sale of equity securities, net \| $									$ 18,614,135	$ 11,567,736
Warrants gross proceeds \| $	$ 3,500,000
Number of years of income that limits distribution \| Y									2
Maximum period between date of financial statements and distribution date									6 months
Ordinary warrants \| $									$ 15,082,443	$ 11,244,239
2024 Public Offering
SHAREHOLDERS' EQUITY
Threshold period for not to enter into an agreement to effect a variable rate transaction, after the closing date of the Offering					180 days		180 days
Threshold period for not to issue, enter into any agreement to issue or announce the issuance or proposed issuance of any ADSs, ordinary shares or ordinary share equivalents, after the closing date of the Offering					90 days		90 days
March 2024 Offering
SHAREHOLDERS' EQUITY
Proceeds from sale of equity securities, gross \| $							$ 6,500,000
Proceeds from sale of equity securities, net \| $							$ 5,500,000
Ordinary shares							811,250
March 2024 Offering \| March 2024 Pre-Funded Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase							3,251,250
Number of ordinary shares for each ADS							1
Exercise price of warrants \| $ / shares							$ 0.0035
March 2024 Offering \| Series D Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase							4,062,500
Warrants, term							2 years
March 2024 Offering \| Series E Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase							4,062,500
Warrants, term							5 years
March 2024 Offering \| American Depositary Shares and Accompanying December 2024 Warrants
SHAREHOLDERS' EQUITY
Price per share, shares issued \| $ / shares							$ 56
March 2024 Offering \| March 2024 Pre-Funded Warrants and Accompanying Series D Warrants and Series E Warrants
SHAREHOLDERS' EQUITY
Price per share, shares issued \| $ / shares							55.9965
Exercise price of warrants \| $ / shares							$ 56
March 2024 Offering \| Existing modified warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase							18,252
Stock offering expense \| $							$ 209,000
Exercise price of warrants \| $ / shares							$ 56
December 2024 Offering
SHAREHOLDERS' EQUITY
Price per share, shares issued \| $ / shares					$ 15.75
Proceeds from sale of equity securities, gross \| $					$ 6,800,000
Proceeds from sale of equity securities, net \| $					$ 5,800,000
Ordinary shares					3,137,778
December 2024 Offering \| American Depositary Shares and Accompanying December 2024 Warrants \| Officers and Directors
SHAREHOLDERS' EQUITY
Proceeds from sale of equity securities, gross \| $					$ 600,000
Ordinary shares					38,095
Shares warrants may purchase					76,190
December 2024 Offering \| Existing modified warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase						200,071
Stock offering expense \| $						$ 1,500,000
Exercise price of warrants \| $ / shares						$ 15.75
December 2024 Offering \| December 2024 Prefunded Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase					11,973,332
Number of warrants or rights exercised									342,095
Number of ordinary shares for each ADS					1
Exercise price of warrants \| $ / shares					$ 0.0035
December 2024 Offering \| December 2024 Prefunded Warrants and Accompanying December 2024 Warrants
SHAREHOLDERS' EQUITY
Combined public offering price \| $ / shares					15.7465
December 2024 Offering \| December 2024 Warrants
SHAREHOLDERS' EQUITY
Exercise price of warrants \| $ / shares					$ 15.75
December 2024 Offering \| Series F Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase					15,111,110
Number of ordinary shares for each ADS					1
Warrants, term					2 years
December 2024 Offering \| Series G Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase					15,111,110
Number of ordinary shares for each ADS					1
Warrants, term					5 years
October 2025 Private Placement
SHAREHOLDERS' EQUITY
Ordinary shares		530,320
Net proceeds \| $	$ 14,900,000
Percentage of gross proceeds of private placement	7.00%
Legal fees and out of pocket expenses \| $	$ 75,000
October 2025 Private Placement \| Directors
SHAREHOLDERS' EQUITY
Ordinary shares		530,320
October 2025 Private Placement \| October 2025 Pre-Funded Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		69,787,865
October 2025 Private Placement \| October 2025 Ordinary Warrants \| Directors
SHAREHOLDERS' EQUITY
Ordinary warrants \| $		$ 128,641
October 2025 Private Placement \| Series H Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		70,318,185
October 2025 Private Placement \| Series H Warrants \| Warrants exercisable term from closing date
SHAREHOLDERS' EQUITY
Warrants, term		5 years
October 2025 Private Placement \| Series H Warrants \| Public announcement for baseline controlled pivotal studies
SHAREHOLDERS' EQUITY
Warrants, term		30 days
October 2025 Private Placement \| Series I Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		70,318,185
October 2025 Private Placement \| Series I, Tranche one warrants
SHAREHOLDERS' EQUITY
Warrants exercisable percentage		50.00%
October 2025 Private Placement \| Series I, Tranche one warrants \| Warrants exercisable term from closing date
SHAREHOLDERS' EQUITY
Warrants, term		5 years
October 2025 Private Placement \| Series I, Tranche one warrants \| Public announcement for monotherapy pivotal trial
SHAREHOLDERS' EQUITY
Warrants, term		30 days
October 2025 Private Placement \| Series I, Tranche two warrants
SHAREHOLDERS' EQUITY
Warrants exercisable percentage		50.00%
October 2025 Private Placement \| Series I, Tranche two warrants \| Warrants exercisable term from closing date
SHAREHOLDERS' EQUITY
Warrants, term		5 years
October 2025 Private Placement \| Series I, Tranche two warrants \| Public announcement for adjuvant pivotal trial
SHAREHOLDERS' EQUITY
Warrants, term		30 days
October 2025 Private Placement \| Series J Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		70,318,185
October 2025 Private Placement \| Series J Warrants \| Warrants exercisable term from closing date
SHAREHOLDERS' EQUITY
Warrants, term		5 years
October 2025 Private Placement \| Series J Warrants \| Public announcement for accelerated or traditional approval for treatment
SHAREHOLDERS' EQUITY
Warrants, term		30 days
October 2025 Private Placement \| Series K Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		70,318,185
October 2025 Private Placement \| Series K Warrants \| Warrants exercisable term from closing date
SHAREHOLDERS' EQUITY
Warrants, term		5 years
October 2025 Private Placement \| Series K Warrants \| Public announcement for sale of priority review voucher
SHAREHOLDERS' EQUITY
Warrants, term		30 days
Maximum \| October 2025 Private Placement \| Series H Warrants
SHAREHOLDERS' EQUITY
Warrants, term		5 years
ADS
SHAREHOLDERS' EQUITY
Stock split			0.028	1					0.028
Ordinary shares									15,152	227,455
Number of warrants or rights exercised									222,801
ADS \| March 2024 Offering
SHAREHOLDERS' EQUITY
Ordinary shares							23,178
ADS \| March 2024 Offering \| March 2024 Pre-Funded Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase							92,893
ADS \| March 2024 Offering \| Series D Warrants
SHAREHOLDERS' EQUITY
Number of ordinary shares for each ADS							1
ADS \| March 2024 Offering \| Series E Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase							116,071
Warrants granted (in shares)							116,071
Number of ordinary shares for each ADS							1
ADS \| December 2024 Offering
SHAREHOLDERS' EQUITY
Ordinary shares					89,651
ADS \| December 2024 Offering \| December 2024 Prefunded Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase												342,095
ADS \| December 2024 Offering \| Series F Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase					431,746
ADS \| December 2024 Offering \| Series G Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase					431,746
ADS \| October 2025 Private Placement
SHAREHOLDERS' EQUITY
Ordinary shares		15,152
Percentage of ordinary Shares outstanding		4.99%
ADS \| October 2025 Private Placement \| Directors
SHAREHOLDERS' EQUITY
Ordinary shares		15,152
ADS \| October 2025 Private Placement \| October 2025 Pre-Funded Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		1,993,939
Exercise price of warrants \| $ / shares		$ 0.0001
ADS \| October 2025 Private Placement \| October 2025 Ordinary Warrants \| Directors
SHAREHOLDERS' EQUITY
Combined public offering price \| $ / shares		$ 8.49
ADS \| October 2025 Private Placement \| Series H Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		2,009,091
Exercise price of warrants \| $ / shares		$ 9.075
ADS \| October 2025 Private Placement \| Series I Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		2,009,091
Exercise price of warrants \| $ / shares		$ 10.3125
ADS \| October 2025 Private Placement \| Series J Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		2,009,091
Exercise price of warrants \| $ / shares		$ 12.375
ADS \| October 2025 Private Placement \| Series K Warrants
SHAREHOLDERS' EQUITY
Shares warrants may purchase		2,009,091
Exercise price of warrants \| $ / shares		$ 12.375
Alumni Purchase Agreement
SHAREHOLDERS' EQUITY
Stock offering expense \| $										$ 112,000	$ 34,000
Floor price \| $ / shares													$ 1
Minimum commitment amount \| $													$ 4,000,000
Maximum commitment securities value \| $													240,000
Commitment amount \| $													$ 8,000,000
Alumni Purchase Agreement \| ADS
SHAREHOLDERS' EQUITY
Purchase agreement period								180 days