Revenue and government financing for research expenditures (Tables)
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12 Months Ended |
Dec. 31, 2025 |
| Disclosure of disaggregation of revenue from contracts with customers [abstract] |
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| Disclosure of revenue from collaboration and licensing agreements |
| | | | | | | | | | | | | | | | | | | Year ended December 31, | | (in thousands of euro) | 2023(1) | | 2024 | | 2025 | | Proceeds from collaboration and licensing agreements | 50,725 | | | 10,505 | | | 620 | | | of which monalizumab agreement - AstraZeneca | 9,499 | | | 4,404 | | | 220 | | | of which IPH5201 agreement - AstraZeneca | — | | | — | | | — | | | of which preclinical molecules agreement - AstraZeneca | — | | | — | | | — | | | of which Sanofi agreement 2016 | 2,000 | | | 4,000 | | | — | | | of which Sanofi agreement 2022 - ANKET IPH62 - Recognition of license initial payment and income related to the completion of work in line with the joint research program | 18,873 | | 401 | | 400 | | of which Sanofi agreement 2022 - ANKET IPH67 -Recognition of license initial payment and income related to the progress of related research program | 15,800 | | 1,700 | | — | | of which Takeda agreement 2023 | 4,553 | | — | | | | | | | | | | Invoicing of research and development costs (IPH5201) | 1,165 | | | 2,060 | | | 1,666 | | | | | | | | | Others | 11 | | | 56 | | | 501 | | | Revenue from collaboration and licensing agreements | 51,901 | | | 12,622 | | | 2,787 | |
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| Disclosure of changes in deferred revenue and collaboration liabilities |
Change in monalizumab deferred revenue (in thousands of euro): | | | | | | | | | | | | | | | | | | | As of December 31, 2022 | 14,481 | | | | Revenue for the 2023 financial year | (9,499) | | | Transfer from collaboration liabilities | 173 | | | As of December 31, 2023 | 5,156 | | | | Revenue for the 2024 financial year | (4,404) | | | Transfer from collaboration liabilities | (536) | | | As of December 31, 2024 | 215 | | | | Revenue for the 2025 financial year | (220) | | Transfer from collaboration liabilities | 5 | | As of December 31, 2025 | — |
Change in monalizumab collaboration liablities (in thousands of euro): | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Current | Non-Current | Total | | As of December 31, 2022 | 10,223 | | 52,988 | | 63,211 | | | Additions (2) | 7,785 | | (7,958) | | (173) | | | Repayment cost to AZ | (8,423) | | — | | (8,423) | | Fx impact | (1,938) | | — | | (1,938) | | | As of December 31, 2023 (3) | 7,647 | | 45,030 | | 52,677 | | | Additions | 4,303 | | (3,902) | | 401 | | | Repayment cost to AZ | (7,772) | | — | | (7,772) | | Fx impact | 3,265 | | — | | 3,265 | | | As of December 31, 2024 (4) | 7,443 | | 41,128 | | 48,571 | | | Additions | 9,521 | | (9,380) | | 141 | | | Repayment cost to AZ | (4,792) | | — | | (4,792) | | Fx impact | (5,671) | | — | | (5,671) | | | As of December 31, 2025 (5) | 6,501 | | 31,748 | | 38,249 | |
Change in deferred revenue relating to the 2022 research collaboration and licensing agreement : | | | | | | | As of December 31, 2022 | — | | | Additions | 8,200 | | | Deductions | (2,874) | | | As of December 31, 2023 | 5,327 | | | Additions | — | | | Deductions | (2,101) | | | As of December 31, 2024 | 3,226 | | | Additions | — | | Deductions | (400) | | As of December 31, 2025 | 2,826 | | | | | | | | |
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| Disclosure of variance of deferred revenue |
The main variance of the global deferred revenue is presented in the following schedule:
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | (in thousands of euro) | | December 31, 2022 | | Recognition in P&L | | Proceeds | | Transfer from collaboration liabilities | | December 31, 2023 | | Monalizumab | | 14,481 | | | (9,499) | | | — | | | 173 | | | 5,155 | | | | | | | | | | | | | | Sanofi services | | — | | | (374) | | | 3,200 | | | — | | | 2,826 | | Sanofi options | | — | | (2,500) | | 5,000 | | — | | 2,500 | | | | | | | | | | | | | Total | | 14,481 | | | (12,373) | | | 8,200 | | | 173 | | | 10,483 | |
(1)Of which €5,865 thousand of current deferred revenue and €4,618 thousand of non-current deferred revenue.
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | (in thousands of euro) | | December 31, 2023 | | Recognition in P&L | | Proceeds | | Transfer from collaboration liabilities | | December 31, 2024 | | Monalizumab | | 5,155 | | | (4,404) | | | — | | | (536) | | | 215 | | Sanofi options | | 2,500 | | | — | | | — | | | — | | | 2,500 | | Sanofi services | | 2,826 | | | (2,100) | | | — | | | — | | | 726 | | | Others | | — | | — | | — | | — | | — | | Total | | 10,483 | | | (6,504) | | | — | | | (536) | | | 3,441 | | (2) |
(2) Of which €616 thousand of current deferred revenue and €2,825 thousand of non-current deferred revenue.
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | (in thousands of euro) | | December 31, 2024 | | Recognition in P&L | | Proceeds and other increase | | Transfer from collaboration liabilities | | December 31, 2025 | | Monalizumab | | 215 | | | (220) | | | — | | | 5 | | | — | | | Sanofi options | | 2,500 | | | — | | | — | | | — | | | 2,500 | | | Sanofi services | | 726 | | | (400) | | | — | | | — | 326 | | | | | | | | | | | | | | Total | | 3,441 | | | (620) | | | — | | | 5 | | | 2,826 | | (3) |
(3) Of which €2,825 thousand of current deferred revenue.
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| Disclosure of government financing for research expenditures |
The total amount for government financing for research expenditures recorded as other income in the income statement can be analyzed as follows: | | | | | | | | | | | | | | | | | | | Year ended December 31, | | (in thousands of euro) | 2023 | | 2024 | | 2025 | | Research Tax Credit | 9,729 | | | 7,463 | | | 6,186 | | | Grant and other tax credit (1) | — | | | 25 | | | 19 | | | Government financing for research expenditures | 9,729 | | | 7,488 | | | 6,205 | |
(1) As of December 31, 2025, the amount is composed of the research tax credit calculated and recognized for the 2024 financial year for an amount of €6,186 thousand.As a reminder, as of December 31, 2024 and 2023, the amount is mainly composed of the research tax credit calculated and recognized for the 2023 financial year for an amount of € 7,463 thousand and €9,729 thousand.
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