v3.26.1
Commitments under Research and Collaboration Agreements (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2025
Mar. 31, 2022
Dec. 31, 2025
Dec. 31, 2025
Dec. 31, 2024
Commitments under Research and Collaboration Agreements [Line Items]          
Clinical development milestones       $ 14,000  
Regulatory events       80,000  
Commercial sales       150,000  
Milestone payments commercial milestones       12,000  
Accrued royalties     $ 52 52 $ 25
Extension royalties   $ 225      
Accrued extension royalties     200 200 200
Development milestones       32,500  
Annual sales milestone payments       $ 50,000  
Net profits from licensed product sales       50.00%  
Payment of development milestones $ 3,300        
Accrued amount         3,300
Derecognize liability     3,300    
Accrued liabilities     325 $ 325 325
Research and Development Expense [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments       70,000  
Royalties amount       25 25
MedImmune License Agreement [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments       244,000  
NCI License Agreement [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments       3,995  
Royalties amount       25  
MSK License Agreement [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payment upon achieving     10,500    
Milestone payment on net sales     30,000    
VAZYME License Agreement [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments       200  
Accrued liabilities     200 200 200
Accounts Payable [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments     790    
Accounts Payable [Member] | MSK License Agreement [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments         790
Other Accrued Expenses and Accounts Payable [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Patent costs reimbursements       273 273
Other Accrued Expenses [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Patent costs reimbursements       169 $ 169
VAZYME [Member] | VAZYME License Agreement [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Milestone payments       $ 11,100  
Minimum [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Royalties amount     20    
Maximum [Member]          
Commitments under Research and Collaboration Agreements [Line Items]          
Royalties amount     $ 30